“Arcanum: Of Steamworks & Magick Obscura”
"If you make people think they’re thinking, they’ll love you; but if you really make them think, they’ll hate you." —Don Marquis
Space hobo
Psychonauts still needs a sequel
納豆 post-processor
Jagged Alliance...no just a third one, but a remake of the first one.
The Jedi Knight series. But only if the plot was based on Jedi Academy's Dark Side ending.
"Wax on, wax off..." "But Mr. Miyagi, I don't see how this is helping me do Karate..." "Pubic hair is weakness, Daniel-san!"
I'm an Irene!
...Oh, wait, only one? Quest 64, then. Sonic Battle was fun, yes, but it definately finished off the story well, without rediculous cliffhangers.
Quest 64 thread
Master Of Orion, many of Civilization's other old competitors too. Oh, and although I actually liked D3, a back-to-basics Descent game would probably do really well.
Note to everybody: READ THE OP, STOP TALKING ABOUT SEQUELS.
@Tofunator: Nah, I think Bungie always did their best work on new Genre Launch IPs. PiD, Marathon, Myth, Oni, the pre-Pipe Shooter Halo… If you've got ut99 kicking around, you might want to check out Marathon: Resurrection
though.
I don't want a Commander Keen reboot, I want The Universe is Toast! Reboot does not mean sequel.
Face Time
Jade Empire.
Eric: The OP didn't elaborate on sequels. Or much of anything, really.
Star Tropics. Preferably handled by Retro once they're done giving Donkey Kong his due.
Ecco The Dolphin. Just tell us what happened after Tides, darnit! A Mega Man 9-style reboot would be bliss. Hell, bring back the sequel to Defender while we're at it - I wanna see the narwhals.
It's just kinda maddening to have the series in this weird limbo where it's released on everything ever as a Sega Classic but shows no signs of ever being continued.
edited 9th Oct '10 1:26:11 AM by SparkyLurkdragon
"In distress", my ass.
todbot, the thread title did specify "reboot", though. 
Departed days ahead.
Sly Cooper. I love inFamous and all, but seriously Sucker Punch, give me my thieving needs! Bald guy with lightning < Awesome thief raccoon.
edited 9th Oct '10 6:13:43 AM by Phoenixor
I guess we could go... wherever we please.
The Showrunner of Dzwiedz 24
Anachronox. Awesome concept and execution decent enough to interest me.
"what the complete, unabridged, 4k ultra HD fuck with bonus features" - Mark Von Lewis
I would reboot every single franchise mentioned above, only for them to be In Name Only reboots.
:D
"keionbu ni yokusou, nyan?"
Syphon Filter.The Jedi Knight series. But only if the plot was based on Jedi Academy's Dark Side ending.
Harbinger of Something
@Eric DVH: Interesting. I'll be sure to check that out when I have the time.
Anyway, I guess my next candidate would be System Shock. Even though its never going to happen. 
The Showrunner of Dzwiedz 24
"Tommy? What's the matter...lover? Don't you like the new me? Hahahaha..."
"what the complete, unabridged, 4k ultra HD fuck with bonus features" - Mark Von Lewis
NOT THE BEES
Command And Conquer. There is no series after Yuri's Revenge.