These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Angst? What Angst?: The whole reason Koishi sealed off her Third Eye in the first place was because of the fear and hatred directed at the mind-reading satori species. Now, however, she simply bounces back really quickly (though this can be attributed to Flandre's presence). In general, Muffin goes out of his way to avoid angst anyway...
Memetic Mutation: Among the fans, "MISSION FAILEO" is a minor meme (owing to Marisa Gear Solid and a block-font in which D was identical to O, with a Lampshade Hanging in Create.swf Adventures).
Older Than They Think: A number of fans have mistakenly thought that Muffin created Meimu (who existed for years before Muffin decided to use her). Of course, they have nothing on the one fan who thought that Muffin had created and popularized Flandre x Koishi...
Schedule Slip: The comic's main page says "updates Sundays and a few Thursdays" but lately it's become (early Mondays, sometimes up to a day later). Actual missed updates are rare, but they do happen.
Rooting for the Empire: In the confrontation with Yasora in Create.swf Adventures, Muffin forgot to include a single line which would have made it much more clear that Yasora intended to burninate the countryside; he added it back in after he realized this (after the fight was over!), but there were several readers who felt that the fight wasn't really all that justified.