These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
One of the final missions, "Light My Pyre". The mission begins with a highly annoying car chase that wouldn't be so bad, except you have to escort Lance, who is riding a motorcycle and seems to enjoy getting in your way (sometimes, even in your line of fire) and getting himself killed, which is a Game Over. Then, you have to fight through a small army of heavily armed, respawning goons to get around the back of a building and through a door. THEN, you have to fight Armando Mendez, who is wielding a flamethrower. If that weren't enough, you're forced to fight him in a disorienting top-down perspective — not to mention, his goons storm in and fight you, as if a man setting you on fire with a flamethrower wasn't enough. (This part is made almost laughably easy if you have a minigun with you, but if you don't...) And if you die? Back to the beginning. And if you do finish it? You find that Louise, the woman you went through all this hell to save, is dead.What fun!
"High Wire". Picking up a few cargo containers of the backs of slow-moving trucks with a sky crane isn't too hard, even with the wonky helicopter controls. However, once you have to fly all the way over to the other island and pick up Diego's small, fast-moving car while he's being chased by armed bikers, those chopper controls will make you want to tear your hair out.