In Spoilsbury Toast Boy, the doctor beetle explains to Liache that "mucus is a living thing" and "it has a certain degree of intelligence." The beetles later drown Liache when her mucus tells them she doesn't deserve to breathe.
In the Global Guardians PBEM Universe, while intelligent apes have been given full civil rights, robots, androids, and other artificial intelligences are still not considered people in the legal sense even though they cannot be harmed with impunity (property laws come into consideration). Demons, the undead, and most other forms of monster are free targets, however.
Deconstructed in this Video Game Confessions which reimagines Samus as a violent torturer and serial killer. She asks "Why is it that when you kill an alien from another world, you're considered a hero?"
Played for laughs in a The Runaway Guys playthrough of Mario Party during the mini game Shy Guy Says when ProtonJon is horrified when the Shy Guy leaves Wario to drown in the ocean, but ignores Yoshi when the same thing happens to him right afterwards.
Chuggaa: And you say I'm racist?
Jon: Ra... How is that racist? It's a dinosaur!
Chuggaa: Dinosaurs are people too.
Jon: No, they're not! They're dinosaurs, that's why we call them dinosaurs!
When Straizo uses the Ripple on Dio's elite zombies during a scene in Vaguely Recalling JoJo, he spares Page because Page had an almost human-like appearance. Also, Page looked like Pesci, who will make an appearance in Vento Aureo.
RWBY: Penny calls her creator "father" but is insecure about the fact she's not a real girl; Atlas regards her as a military secret so even her team mates don't know what she is. Ironwood's stated mission is to replace human armies with robots to protect human life, and Penny believes her purpose is to save the world. Ruby tells Penny she does have a soul, but Penny's team mate associates with her only because ordered. Cinder tricks Pyrrha into publicly killing Penny to expose Penny's secret and frame Atlas for Vale's invasion. Penny's death focusses on her body shredding inhumanely like metal then on the very human loss of light and life from her eyes. While Ironwood calls Penny a "girl" not a "robot", he seems less concerned with her death than with Ozpin's possible reaction to the reveal; this is unlike both Ruby and Pyrrha who are devastated despite knowing she's a robot.
They said that thoughtforms weren’t really people. They looked like people, sure, and acted like people. But a ray gun made out of lio could shoot real plasma rays, even if the inside was a black box that shouldn’t work by any world’s rules. In the same way, they said, a thoughtform could have ‘real’ feelings, but they weren’t the same kind of feelings everyone else had- they were just part of the illusion, there to make thoughtforms more like humans. They didn’t have souls, so any emotions they had were meaningless- hollow as a mannequin’s head.
Blake: And the graphic and extensive violence was totally okay because it was a ROBOT and not a PERSON!
SCP Foundation is an interesting case. The Foundation insists on containing all SC Ps, even those that are sentient and have not been shown to pose any danger. However, at least in some stories, they have strict ethical standards regarding how to treat SC Ps, unlike some other organizations in the same universe. It's also worth noting that they're perfectly willing to sacrifice human lives in the interests of their mission; their general attitude towards both humans and SC Ps is to do whatever it takes to reliably contain them, but not to be any crueller than is necessary in doing so.