Development Hell: "Princess Pi vs. Dr. 8" appears to have entered this. The list of Princess Pi villains released back in 2011 showed a drawing of Dr. 8, and described his gimmick as using mathematical calculations to determine the most effective evil schemes. Additionally, a post Peter made on the Toon Zone forum compared his personality to that of Charlie Sheen. Despite all these details, Peter never gave a release date for the story.note He didn't even officially confirm the title, "Princess Pi vs. Dr. 8", but the fact that it fits the Idiosyncratic Episode Naming makes it a likely guess. For all we know, he might never produce it.
Even earlier than that, after Peter Paltridge wrote some bios for Electric Wonderland characters, and updated the ones for Mulberry and Keiki, he placed the symbol next to redrawn links to all the series' character bios. This provided the first hint that a new Platypus Comix series was in store.
Peter originally designed Princess Pi as a little girl, but then he considered the possibility that more people would want to read about a hot, older princess.
The original list of Princess Pi villains portrayed the Totally Nazis as fascist versions of the Totally Spies! leads.
If the Alpha Bitch trope still had its original title, "The Libby," then "Princess Pi vs. The Alpha Bitch" would have a correspondingly different title, and Pi's first appearance in that story would have gone like this.
Opposite Guy's inclusion on the aforementioned baddie roster, and the ending of "Princess Pi vs. Opposite Guy", suggest abandoned plans for him to become a regular enemy.