- Hey, It's That Voice! - Michael McConnohie, who voices the Agency Director.
- And in the (Latin American) Spanish voice track, Carlos Segundo. Also known as Piccolo from the Mexican dub of Dragon Ball Z.
- Cam Clarke voices PCNN reporter Chad Stroker in his audio logs.
- Dr. Warren Vidic is the Freak Watcher.
- Gear is numerous Cell Soldiers.
- Catalina Thorne is voiced by none other than Cree Summer.
- Market-Based Title: Crackdown is called Riot Act in Japan.