Albegas: Out of the three main Color-Coded Characters, Daisaku is black, Tetsuya is blue and Hotaru is red. She plays this straight and takes her mission seriously, wanting to be the hero her father raised her to be.
Kaneda from AKIRA is an example with his iconic all-red biker outfit and souped-up red power bike.
The title hero of Anpanman wears a red superhero uniform. One of his allies, Shokupanman, has red as his accent color for his uniform. This is taken to the extreme in the movie Ruby's Wish, where Ruby, the red Aurora Girl automatically believes Anpanman is the best superhero ever just because he wears red, even before seeing his heroic deeds.
Protagonist Ichigo Kurosaki both plays this trope straight and subverts it, his coat in Bankai form is red on the inside and gives his spirit energy a red tint to it and his Hollow Mask has red markings on it and his hollow uses a red Cero.
The name of Kisuke Urahara's Zanpakuto is Benihime (Japanese for "Crimson Princess"). In shikai mode, it can produce and manipulate a crimson-colored energy for various techniques.
In Case Closed it is discussed when they act the "Peach boy" legend. Conan is told he can't be the hero because he wants to wear blue, his color code, but the kids say the hero wears red.
Code Geass: Kallen Kouzuki is easily the most morally unambiguous character on the show and her outfits — no, just about everything about her — is red. Red pilot suit, mostly red mecha and naturally her short red hair.
Daitarn3: Banjo's combat suit is dark-red. He also wears a red jacket.
Most Digimon protagonist Mons are red (or orange, which is close enough to establish a pattern): Agumon (both Adventure and Savers versions, though their Rookie forms are more on the yellow side), Guilmon, Agnimon, and Shoutmon; plus their evolutions. Gatchmon is mostly grey, but he has a big red helmet and evolves into mostly-red forms. Gammamon is mostly white, but his horns are tipped with red and one of his evolutions is predominately red. The exceptions are Veemon (blue) and Gumdramon (purple), both justified since they each share a continuity and screentime with one of the above red/orange characters and have to set themselves apart.
When Takato is designing Guilmon in the dub of Digimon Tamers, he comments that red is "definitely a power color."
Goku typically wears clothing in shades of either red or dark orange, the Kaioken and Super Saiyan God transformations are both red, and he's The Hero of the series.
Gohan's Great Saiyaman outfit has a red cape.
In Fullmetal Alchemist, Edward Elric is often seen wearing a red coat. It's even commented that Edward must be a hero because he wears red. He responds that he's no hero — he just thinks that the color looks badass.
Getter Robo series spots Getter 1/Dragon/Shin Getter-1 (leader's unit) with red as the main color.
Oddly, the Getter Robo Go/Neo Getter-1 is blue with red markings. Its Getter Robo Shou/Neo Getter-2 that's red. Still heroic, though.
Gundam has a strange love/hate relationship with this trope as characters wearing red or Mobile Suits sporting mostly red are designated The Rival. However, many Gundams tend to carry red shields, especially in the Universal Century. One suit that plays this trope straight is the Build Burning/Try Burning/Kamiki Burning Gundam of Gundam Build Fighters Try.
Kagerou Project: Invoked and discussed by Ayano, to convince her adoptive siblings Kido, Seto and Kano that their red eyes aren't monstrous, but marks of heroism. It's also the reason why she wears her iconic red scarf. It's no coincidence that Shintaro also wears red at least, in the timelines where he manages to move on with his life.
Shintaro wears the red jacket because Ayano thinks it suits him.
In the Mazinger series, all heroes of the trilogy — Kouji Kabuto, Tetsuya Tsurugi and Duke Fleed — wear red outfits. Also, Mazinger and Great Mazinger's iconic chestplates are red.
Maoyu: The main female lead is the Demon Queen, a woman with red hair, red eyes and a preference for red clothing. Despite being a demon, she is with no doubt the most heroic character in the series, as her main goal is to end the war with as little bloodshed as possible and bring lasting peace for both humans and demons alike.
My Hero Academia: Eijiro Kirishima goes by the hero name "Red Riot" in emulation of his idol, Crimson Riot. He's a Book DumbHot-BloodedNice Guy and is always the first one to jump into the fray to protect others with his Quirk, Hardening. To add to the point, his hair, eyes, and costume are all deep red. This is also a conscious decision on his part, as his hair is naturally black, and he actively projects his Hot-Blooded exterior to hide his insecurities.
The Hokage hat, and Naruto and Minato's Hokage cloaks red and white.
Hashirama Senju wears red ninja armor.
Mei Terumi, the fifth Mizukage, has auburn hair and is the most openly friendly of the five Kages next to Gaara.
Onoki, the third Tsuchikage, has a distinct red nose.
In Neon Genesis Evangelion, Asuka wears a red plugsuit and pilots a red Humongous Mecha. She's not the main character and an Anti-Hero as opposed to a regular one, but she's one of the heroes nonetheless.
In One Piece, the colour that represents Monkey D Luffy is red according to Oda and he wears a red top for most of the series and other bright colours. Luffy's idol is Red Haired Shanks who is considered a Big Good across the sea, and Shanks's captain is Gold D Roger The Pirate King who — yeah, you guessed it — wore red.
Gene Starwind's red hair is actually commented on multiple times in Outlaw Star in conjunction with the fact that he carries a Caster (a special weapon that fires bullets that contain magic spells. Exactly why the fact that he's a redhead with a magic gun is never actually explained. He also has the Outlaw Star painted red as well.
Panzer World Galient: The titular mecha is nearly completely red. The Hero Jordy also wears black and red armor and bodysuit.
Saint Seiya: The Hero Seiya wears a red shirt. Also, when he wears his armor, the clothes under it are red. This is only in the anime, though: in the manga, he and everyone else wears white under the Cloth.
Maka, the heroine of Soul Eater, wears a red skirt as a part of her primary outfit and also wields a red scythe.
In the parody anime Special Duty Combat Unit Shinesman, the protagonist is interviewing for an office job and one of the questions he's asked is "What's a good color for a superhero costume?"; he says red because his little brother had told him that heroes always wear red. It eventually turns out that the company is a front for a Super Sentai-style hero group, and he gets made the Red Ranger and therefore The Leaderentirely because of his answer (the other interviewees gave business-safe answers like sepia, gray, moss green, and salmon pink).
Asuna from Sword Art Online starts out with a red vest, and some of her later outfits have some red, but as an Undine, she ditches the red for blue.
Klein is a straighter example and even has a small Red Oni, Blue Oni motif with Kirito (whose early avatar has Blue Is Heroic before he switches to Dark Is Not Evil later on). In ALO, he keeps it by using a Salamander avatar.
Heathcliff is mostly dressed in Red Armor while his Knights of Blood has only a minor amount of red in their clothing. However, it's subverted with Heathcliff (who turns out to be Akihiko Kayaba, the Big Bad) and Kuradeel (who turns out to be a member of Laughing Coffin).
In Tamagotchi, Gotchiman, a superhero character from the Show Within a Show of the same name, wears a red mask, cape, and belt.
Gurren Lagann, it's even in the title ("Gurren" comes from guren, an intense shade of red, which The Other Wiki — in Japanese — likens to "infernal flames").
Vash the Stampede (or Stampeed, depending on your source) from Trigun wears a large red coat and is the most heroic of all the characters, plus he's a pacifist.
Keith/Akira of Voltron/GoLion wears red and is the leader of the team. Oddly, his mecha (which forms the head and torso) is black, while the red mecha is ridden by Lance/Isamu, who wears blue.
During the Battle City arc, Yugi, Kaiba and Marik each wielded one of the three Egyptian God cards. Yugi's was Osiris the Heaven Dragon, a fearsome red dragon.
Jonouchi is a hero and has three notable monsters with red themes. His Flame Swordsman has a red helmet and robe. His Red-Eyes Black Dragon has, well, red eyes. And his Claw of Hermos dragon which he acquired during a filler arc is a red-scaled dragon.
In both the Yu-Gi-Oh! GXanime and manga, Judai likes the color red, even though Osiris Red is the lowest ranking dormitory. In the manga, it's also the color his idol Koyo Hibiki favors. He ultimately shows up for his duel with Koyo in the Distant Finale wearing his school uniform.
Yu-Gi-Oh! ARC-V, Yuya is an All-Loving Hero with red eyes and partly red hair, a red shirt and shoes, and his ace Odd-Eyes Pendulum Dragon is a red dragon. It's a bit more complicated as Yuya is an Apocalypse Maiden with his ace once willingly destroying a dimension.
Yusei rides a red D-Wheel and wears a red helmet while doing so.
Jack's signature monster is the Red Daemon's Dragon, and it is one of the two most prominent dragons of the Signer Dragons, having defeated several of the strongest villain monsters.
Aki has dark burgundy hair and her outfit includes a red corset and red high-heeled pumps.
All of the main heroes have red tattoos that are a part of the Crimson Dragon to symbolize their chosen one status.
