- I got so much new respect for Slither when I realised that the main characters are all subversions of their traditional roles in horror. Including the villain. Especially the villain. -Whatever
- Nathan Fillion once noted he loved Pardy for his very human, "What the fuck?" reaction early on, rather than instantly donning the boots of asskicking.
- Fridge Brilliance: The only ones that survive are the ones willing to learn and adapt, in other words evolve, like Starla was teaching earlier in the film.