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It may be part of the Goosebumps series.
That sounds similar to a book I read in 4th grade. I remember the "weather prediction as a family trait" part and it being about two brothers. Were they travelling on their own for some reason? Was there another family with similar powers who were rivals of some sort? I think I remember something about how trying to use your ability for profit makes you lose it. I definitely remember a scene where they convince a bus driver to drive into a ditch when one brother senses a tornado coming. I think it was called "Storm Chasers" or something similar, but I may be thinking of a different book entirely. It may have been part of a series.
Edit: I haven't had any luck searching for "Storm Chasers", so that's probably not what it's called, but I'm pretty sure it was close. Darn, now I want to know too...
Edited by ladyofprocrastination
Could it be In The Eye of the Tornado, the first book of the Disaster Zone series? Found it on Amazon.
A book I started reading some time between 2nd and 5th grade about two brothers. Weather prediction of some sort was a family trait and I think only one of the brothers had it. They may have been raised by a grandfather? I remember them heading off to a Springfield and realizing they had predicted an event in the wrong one. I believe I read it sometime between 1995 and 1999.
Edited by northernspy