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4* ''Franchise/DotHack'':
5** The [[BigBadDuumvirate Main Antagonists]] of the [[OneGameForThePriceOfTwo first four games]] are [[DeusEstMachina Morganna Mode Gone]], who seeks to kill [[BigGood Aura]] to preserve her own existence, and [[AIIsACrapshoot Cubia]], [[OutsideContextProblem who mysteriously appeared after]] [[DiscOneFinalBoss Skeith's]] [[OutsideContextProblem defeat.]]
6** ''VideoGame/DotHackGU'' has the mysterious Tri-Edge, the Player Killer [[AntiHero Haseo]] has been hunting, who was later revealed to be [[spoiler:[[BigBadFriend Ovan]]]]. [[spoiler: [[HijackedByGanon Cubia]] takes this role from [[DiscOneFinalBoss Ovan]] after the latter's defeat.]]
7*** The [[VideoGameRemake Last Recode]] Exclusive Vol. 4 has [[spoiler:the Moralta, [[OutsideContextProblem a monster originating from outside The World]] that's rapidly consuming it's data]].
8* ''VideoGame/TwelveThirteen'': The Man in Glasses [[spoiler:turns out not to be. He's the only person who was actually on your side throughout the entire game, while everyone else -- including your apparent "ally" that he kills -- were trying to stop you from performing the mission you were created for, believing you were too irretrievably damaged to be successful]].
9* ''VideoGame/OneBitHeart'': [[HiddenVillain The Hacker Boss]] is the one who hired the hackers to cause chaos and is behind the plot to hack the [[MasterComputer Master Program]]. [[spoiler:He's [[TreacherousAdvisor Mikado Aisaka]], actually Nanashi from the future, who wanted to [[AssimilationPlot unify all humanity with a single mind]] for world peace and therefore prevent a BadFuture.]]
10** ''VideoGame/OneBeatHeart'': [[spoiler:Shinobu Kasuga]], the SerialKiller responsible for all the murders of the game.
11* ''VideoGame/TwoDark'': [[spoiler: Dr. Sergei Krach is the one who killed Mr. Smith's wife, kidnapped and brainwashed his children, and the mastermind about the disappearing of the other children in Gloomywood]].
12* ''VideoGame/SixteenWaysToKillAVampireAtMcdonalds'': The titular vampire wants to drain the cashier's blood, and Lucy must find a way to kill him before he does.
13* ''VideoGame/ThreeInThree'': As the site notes, there are [[BigBadEnsemble three antagonists]] that 3 faces in her quest to return to the spreadsheet by repairing the computer:
14** The Misfit Vowels are an army of corrupted vowels that are running amok and causing much of the damage to the computer, and 3 must capture them to stop them.
15** The Anti-Virus Robot wants to delete 3 as it sees her as a glitch or virus. Though, in practice, it does little to get in her way.
16** [[spoiler:The pi symbol]] is the one using the misfit vowels to destroy the word processor so he can [[FinalSolution wipe out all letters]] and prove that numbers are superior. Of the three, he is the main threat.
17* ''VideoGame/EightBitKiller'': The conflict is driven primarily by Master Brain, an alien who commands an army of humans to destroy [[AfterTheEnd what's left of humanity]] under the pretense of promising a new dawn.
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21* ''VideoGame/AbsentedAgeSquarebound'': There isn't a clear main antagonist at first, but after Karen completes the Park Driftworld, [[spoiler:her most important Heart Fragment is stolen by a more intelligent than average Ganger. Said Ganger is the leader of a pack of weaker Gangers, and intends to steal Karen's identity and use her powers to merge reality and the Driftworlds, all to make it easier for Gangers to consume people's Heart Fragments. However, the Gangers aren't responsible for Karen becoming a ghost in the first place, which is a mystery left for the sequel]].
22* ''VideoGame/AbyssCrossing'': The one behind the Astras going out of control is [[spoiler:Creation Goddess Siro, who requested Destruction Goddess Kuro to cause chaos in the multiverse. This is so heroes from across the multiverse will band together to defeat the Astras and challenge Siro, granting the latter the [[BloodKnight epic battle she desires]]]].
23* ''VideoGame/{{Acrylic}}'': [[spoiler:[[MadArtist Brittany/The Collage]]]] is the one who killed the girls and turned them into the [[VengefulGhost spirits]] haunting Acrylic Academy and is keeping Nicole and Joelle Chapman trapped inside.
24* ''VideoGame/AdvancedVariableGeo'' series: [[EvilMatriarch Miranda Jahana]] is the [[CorruptCorporateExecutive founder]] of [[ResearchInc Section-9]] who created the hybrids and is using the tournament to test them and create the perfect fighter/bio-weapon. She also desires to break [[TheHeroine Yuka Takeuchi]] for getting in her way.
25* ''VideoGame/AdventRising'': [[AGodAmI The Koroem]], a being responsible for summoning the Seekers, an alien race Gideon must prevent from wiping out all of humanity.
26* ''VideoGame/AdventureQuestWorlds'' has Drakath, the Champion of Chaos, who is sending out thirteen Lords of Chaos to terrorize the land of Lore, and who killed [[spoiler:Sepulchure]], who was the BigBad in most of Creator/ArtixEntertainment's other games.
27* ''VideoGame/AITheSomniumFiles'': [[spoiler:Saito Sejima]], the identity of the [[SerialKiller Cyclops Killer]] who Kaname Date spends the game hunting down.
28* ''VideoGame/AkujiTheHeartless'': Orad, Akuji's treacherous brother who murdered him on his [[WidowedAtTheWedding wedding night]], leading him on his journey to escape hell and exact his revenge. [[spoiler:However, it's revealed that Orad was being controlled by [[UsefulNotes/{{Voudoun}} Baron Samedi]], who has been using Akuji to gain enough power to escape to the realm of the living.
29* ''VideoGame/AlanWake'': [[EldritchAbomination The Dark Presence]], a sinister otherworldly being stuck at the bottom of a lake, manipulating Alan to [[ClapYourHandsIfYouBelieve write a story to set it free]], all while terrorizing the town of Bright Falls.
30** ''VideoGame/AlanWakesAmericanNightmare'': [[HumanoidAbomination Mr. Scratch]], an avatar of the Dark Presence, still trying to torment Alan so he will set it free from the lake.
31* ''VideoGame/AliceMare'': The Cheshire Cat is the one who trapped Allen and his friends in the Dream and stole the World Keyes.
32* ''Franchise/{{Alien}}'':
33** ''VideoGame/AliensColonialMarines'': Michael Weyland, the face of Weyland-Yutani Corporation who oversaw the kidnapping of hundreds of colonists to be turned into Xenomorph hosts and experimented on.
34** ''VideoGame/AlienIsolation'': [[SuperPersistentPredator The Alien]] drives the conflict [[spoiler:even after it is defeated halfway through]]. [[MasterComputer APOLLO]] also qualifies, since he is responsible for turning turning the [[ArtificialHuman Working Joes]] against the humans on the station and [[spoiler:outlives the Alien]].
35* ''VideoGame/AlisiaDragoon'' has Baldour, the evil being of the Silver Star. His followers are trying to revive him through most of the game, and eventually do succeed... Alisia, of course, tears him a new one.
36* ''VideoGame/TheAllianceAlive'': [[spoiler:Kuwalsa, who seeks to recreate the universe [[InTheirOwnImage in his own image]] because he cannot stand the idea of being "insignificant" in the current one]].
37* ''VideoGame/AloneInTheDark'': Ezechiel Pregzt in the first game, One-Eyed Jack in ''2'', Jedediah Stone in ''3'', Alan Morton in ''The New Nightmare'', and Lucifer in the 2008 game.
38* ''VideoGame/AlphaProtocol'': [[CorruptCorporateExecutive Henry Leland]], who's behind every major crime in the game.
39* ''VideoGame/{{Alundra}}'': Melzas. [[spoiler:Originally a demon from another world, he was impressed by the belief system the humans in this world have, and so manipulates them into worshiping him for him to gain more power.]]
40* ''VideoGame/{{Amea}}'': The one responsible for the title character’s memory loss is [[spoiler:[[EldritchAbomination The Master Eye]], leader of the [[PathOfInspiration Cult of the Eye]] who brainwashes everyone by getting them to gouge their eyes]].
41* ''VideoGame/AmericanMcGeesAlice'': [[spoiler:[[GodSaveUsFromTheQueen The Queen of Hearts]], the manifestation of Alice's madness trying to corrupt her mind]].
42** ''VideoGame/AliceMadnessReturns'': The Dollmaker, A.K.A. [[spoiler:[[PsychoPsychologist Dr. Angus Bumby]], who's trying to get Alice to forget about Wonderland and the house fire to cover his tracks and so he can use her as a prostitute]].
43* ''VideoGame/AmnesiaTheDarkDescent'': [[EvilOldFolks Baron Alexander]], who Daniel sets out to kill [[spoiler:as revenge for manipulating him into killing innocents in order to gather vitae that will allow him to return to his home dimension]].
44** ''Amnesia: Justine'': Justine, who traps the player character in her dungeon and has her navigate through traps and monsters.[[spoiler:Except she turns out to be an amnestic Justine who was testing to see if she still had any humanity.]]
45** ''VideoGame/AmnesiaAMachineForPigs'': [[KnightTemplar The Engineer]] aka [[spoiler:the Machine, who sets out to use his army of manpigs to destroy humanity in order to prevent the atrocities that would occur in the 20th century]].
46* ''VideoGame/AmongTheSleep'': [[spoiler:[[AbusiveParents The Protagonist's Mother]], whose abuse is the source of the game's nightmarish imagery]].
47* ''VideoGame/AnakshaFemaleAssassin'': Each game [[NoAntagonist with the exception of]] ''Quick Stop'' has one.
48** The original game has Vincent St. Claire, a school principal who runs a criminal empire that is the cause of much of the rampant crime in [[WretchedHive Santa Lina]]. His drug dealing was foreshadowed as far back as mission 4, and it's his actions that start [[PlayerCharacter Anaksha]] on her [[VigilanteWoman quest]].
49** ''A Sea of Fire'' has Frank, a local club owner who has plans to import and sell anti-tank weapons to local gangs, which could escalate gang war.
50** ''A New Threat'' has Trent, a drug dealer who is a minion in an organization that is spreading a new drug, “Pixie Dust”, throughout the [[RedLightDistrict Hell's Cats district]].
51** ''Dark Angel'' has Tony Valentino, aka Big-V, the head of his aptly-named [[TheSyndicate V-syndicate]] that is responsible for spreading and dealing Pixie Dust, as well as the kidnapping of Ivonne and the murder of [=DeMartini=], which Anaksha was [[FrameUp framed for]].
52* ''VideoGame/AndysAppleFarm'' [[EldritchAbomination The Entity]], a being that only Thomas can see, who only speaks as a voice in Thomas's head, and through the videogame Thomas is developing [[spoiler: via Peter the Pumpkin]], has dedicated himself to tormenting Andy and his family, [[spoiler:in addition to trapping the Eastwood family inside the game and turning them into Andy and the other characters]].
53* ''Videogame/AngelsOfDeath'': [[spoiler:[[MadDoctor Doctor]] Daniel "Danny" Dickens]] is the one who recruited the other killers of the Tower and brought Rachel to the tower in the first place, and is hell-bent on making sure Ray and Zack never leave.
54* ''VideoGame/AngryBirds'' series: [[KingMook King Pig]] is the leader of the pigs and the one who leads the operations to steal the titular birds' eggs.
55* ''VideoGame/TheAngryVideoGameNerdAdventures'' series:
56** Original game and ''[=RemASSturd=]'': [[spoiler:LJN programmer [[ArchEnemy Fred Fucks]]]] is revealed as the one who sucked the Nerd and his friends into Game Land to force them to experience his latest shitty game.
57** ''VideoGame/TheAngryVideoGameNerdIIAssimilation'': [[spoiler:[[DeusEstMachina Death Mwauthzyx]]]] (original)/[[spoiler:[[MechanicalAbomination The Fuckotron 9000]]]] (remastered) is the being responsible for turning the world into a shitty video game.
58** ''Tower of Torment'' expansion: [[spoiler:Bugs Bunny/The Fucking Rabbit]] kicks off the plot by flipping off the Nerd and insulting his games to lure the Nerd into his Crappy Castle and kill him.
59* ''VideoGame/AnnieLastHope'': [[EvilutionaryBiologist Dr. Edward]], the MadScientist who unleashed the Glaaki virus with the intent of ruling the zombie-ridden world as a god.
60* ''VideoGame/ANNOMutationem'': [[OneLetterName C]], one of the top members of [[NGOSuperpower The Consortium]] who masterminded the capture of Ann's brother, seeks to access the power of Hinterland, an EldritchLocation that holds an ArtifactOfDoom that'll give him the power he needs as part of a plan to reinstate an abandoned project.
61* ''VideoGame/{{Anodyne}}'': The Evil Darkness is the mysterious entity that Young must save the Legendary Briar from. [[spoiler:The endgame heavily implies that the Darkness ''is'' [[LivingMacGuffin Briar]], actually Young's EvilFormerFriend.]]
62* ''VideoGame/AnotherEden'': The Phantom, a powerful inter-dimensional being that wants to [[OmnicidalManiac destroy the universe]]. [[spoiler:Arc 2 reveals that there's a whole race of them seeking the same thing, lead by a red Phantom.]]
63* ''VideoGame/AoOni'': The titular Ao Oni haunts the mansion and tries to kill Hitoshi and his friends.
64* ''VideoGame/ApeEscape'': [[ManiacMonkeys Specter]] leads the titular apes in his plans to TakeOverTheWorld.
65* ''VideoGame/{{Apocalypse}}'': [[EvilutionaryBiologist The Reverend]], a FalseProphet who summons the HorsemenOfTheApocalypse to destroy humanity so he may rule what's left of it.
66* ''VideoGame/ArcAngle'': Fallen Angle, TheRival to the hero who joined the [[BombThrowingAnarchists terrorist organization Defiance]] out of jealousy of the hero, [[spoiler:[[DiscOneFinalBoss but also because he discovered]] Xero-Fin, the [[TreacherousAdvisor supposed]] BigGood, actually plotted with the terrorist programs to attack cyberspace so that he could get fame and recognition by having Arc Angle stop it]].
67* ''VideoGame/ArcTheLad'': [[EldritchAbomination The Dark One]], an ancient evil who seeks control of the entire world.
68** ''Arc the Lad III'': The [=Professor=]/[[spoiler:Ludwig]], the head of the Academy who's willing to go to great lengths to revert the world back to what it was before the Great Disaster [[spoiler:and ends up releasing the Dark One in the process]].
69* ''VideoGame/AriasStory'': [[spoiler:Clyde Harow the Librarian]] is the creator of the dark book world and the monsters inhabiting it, and is the one who trapped Aria inside, [[spoiler:because he wants to test her and see if she can behave like the real Aria]]; on the [[BigBadEnsemble other end]] is [[spoiler:the Rabbit, the InUniverse Big Bad of Lewin's [[ShowWithinAShow story]] that the book world is based on]], who leads the monsters in trying to kill Aria in order to [[spoiler:preserve themselves [[TheStarscream against Clyde's orders]], as Clyde plans on [[YouHaveOutlivedYourUsefulness disposing of them]] if Aria completes her journey]].
70* ''VideoGame/{{Arkanoid}}'' series: [=DoH=], or Dominate Over Hour, is the RealityWarper that attacks the titular mothership and goes after the Vaus spacecraft. In ''Revenge of [=DoH=]'', it takes over the Xorg spaceship to get revenge, and in ''[=DoH=] It Again'', it lures the Arkanoid with a fake planet to destroy Vaus.
71* The ''VideoGame/ArmedWithWings'' series has Vandheer Lorde. He's the series' most recognizable antagonist and serves as the FinalBoss of most of the games. The main exception is ''Armed With Wings 2'', which has Vandheer Lorde as the VillainProtagonist and the Armed With Wings/Lone Warrior the HeroAntagonist. Network is sort of TheManBehindTheMan to Vandheer Lorde in ''Armed With Wings 3''. However, the latter still serves as the FinalBoss while Network is the second-to-last boss.
72* ''VideoGame/AssassinBlue'': [[spoiler:The boss, who forces Blue and Red to kill and intimidate rival territory's politicians to expand his own before Blue rebels against him]].
73* The overarching plot of the ''Franchise/AssassinsCreed'' series has the Templar Order/Abstergo Industries, with Warren Vidic being their most prominently villainous member in the main games. Following [[spoiler: Vidic's death]], Juhani Otso Berg becomes the most prominently seen Templar. [[spoiler:Juno]] was also revealed as a [[TheChessmaster chessmaster]] villain at the end of ''III'', and from then on acts as the GreaterScopeVillain to both factions. Each game also has its own BigBad:
74** ''Videogame/AssassinsCreedI'' has a BigBadEnsemble between [[spoiler:Rashid ad-Din Sinan AKA Al Mualim and Robert de Sablé, rival Templar leaders who seek the Piece of Eden for their own plans]].
75** ''VideoGame/AssassinsCreedII'' has "The Spaniard" revealed to be [[spoiler:Rodrigo Borgia / Pope Alexander VI]]. All the other Templars that Ezio fights in his first twenty years as an assassin work for him and it was him that ultimately ordered the execution of the other male members of the Auditore family.
76** ''VideoGame/AssassinsCreedBrotherhood'' has Cesare Borgia, being the one who attacks Monteriggioni, steals the Apple, kills [[spoiler:Mario]], and is the one all the Roman Templars work for following Rodrigo's defeat.
77** ''VideoGame/AssassinsCreedRevelations'' has [[spoiler:Prince Ahmet]], the true leader of the local templars.
78** ''VideoGame/AssassinsCreedIII'' has [[spoiler:Haytham Kenway]] with [[spoiler:Charles Lee as TheHeavy who pulls a DragonAscendant]]. The [[GreaterScopeVillain Greater Scope Villains]] of the game are [[spoiler:Reginald Birch]] and [[spoiler:Edward Braddock]] as revealed in the novel ''[[Literature/AssassinsCreedForsaken Forsaken]]''.
79** ''VideoGame/AssassinsCreedIIILiberation'' has The Company Man running the New Orleans chapter of the Templars, who turns out to be [[spoiler:Madeleine de L'Isle]].
80** ''VideoGame/AssassinsCreedIVBlackFlag'' has a BigBadEnsemble between Laureano de Torres y Ayala and [[spoiler:Bartholomew Roberts]], with [[spoiler:John]] in the modern segments. [[spoiler:Some could say Aita is the true BigBad, as Roberts and John are his reincarnations.]]
81** ''VideoGame/AssassinsCreedFreedomCry'' has [[spoiler:Pierre, Marquis de Fayet, the racist governor of Port-au-Prince and head of the French forces located there]].
82** ''VideoGame/AssassinsCreedRogue'' has an interesting example of this trope. Considering you are playing as Shay Patrick Cormac, [[VillainProtagonist a Templar]], and do battle with the Assassins, the primary antagonist of the game is Achilles Davenport, though he's portrayed as an UnwittingInstigatorOfDoom who has caused countless innocent deaths through a mix of recklessness and incompetence.
83** ''VideoGame/AssassinsCreedUnity'' has [[spoiler:François Thomas Germain, the usurping Templar Grand-Master and killer (by proxy) of Francois de la Serre]].
84** ''VideoGame/AssassinsCreedSyndicate'' has Crawford Starrick, Grand Master of the British Templars.
85** ''VideoGame/AssassinsCreedOrigins'' has a BigBadDuumvirate example in the form of [[spoiler:Flavius Metellus / The Lion and Lucius Septimius / The Jackal]], the leaders of the Order of the Ancients in Rome and Egypt. ''The Hidden Ones'' {{D|ownloadableContent}}LC on the other hand has Gaius Julius Rufio as the sole Big Bad.
86** ''VideoGame/AssassinsCreedOdyssey'' has the Cult of Kosmos, which is a BigBadEnsemble with [[spoiler:Deimos as TheHeavy and DragonAscendant and both Aspasia (the Ghost of Kosmos) and Agamemnon as [[GreaterScopeVillain Greater Scope Villains]]]].
87** ''VideoGame/AssassinsCreedValhalla'' has a BigBadEnsemble between King Alfred The Great, [[spoiler: who is the Grand Maegester of the English Order of the Ancients and is responsible for reforming the Order into the Templars after his exile had ended, thus making him a GreaterScopeVillain]], and [[spoiler:Basim Ibn Ishaq/Loki, who turns out to be EvilAllAlong and serves as the FinalBoss]]. [[spoiler:Basim also]] takes on the role of the BigBad for the modern day segments of the story alongside [[spoiler:Aletheia]], another GreaterScopeVillain, since the two manipulated Layla Hassan into giving them the Staff of Hermes Trismegistus so that [[spoiler: the former could be resurrected]]. Arguably, [[spoiler:Odin himself]] is also a GreaterScopeVillain since he is a previous incarnation of [[spoiler: Eivor]] and is responsible for the death of Loki's son Fenrir, thus setting [[spoiler: Basim's vendetta against Sigurd, and eventually Eivor, into motion]].
88* ''Videogame/AstralChain'': [[spoiler:Yoseph Calvert, who wants to transcend himself and humanity; [[BigBadEnsemble and]] Jena Anderson, who wants to merge the Astral Plane and Earth]].
89* In the regular storyline of ''VideoGame/AsurasWrath'', Lord Deus and Gohma Vlitra are the primary forces that are plaguing the world that Asura finds himself in. In the GrandFinale DLC, however, it turns out that [[spoiler:Chakravartin, the Creator, is the one responsible for the Gohma, and by extension, all the horrible things the earth gods did to try to fight them]].
90* The ''VideoGame/AtelierSeries'' rarely gets a BigBad. Most of the games have NoAntagonist since they're mainly coming-of-age stories about an alchemist striving to prove themselves to the world, with the FinalBoss often being a GiantSpaceFleaFromNowhere that only serves as the final test for the alchemist to overcome. There are a few exceptions, however.
91** ''VideoGame/AtelierIrisEternalMana'': Mull is an alchemist who abuses mana believing that it will benefit humanity and serves as the {{Foil}} to Iris and Klein. Towards the end of the game, [[spoiler:he gets usurped and killed by his own creation, [[EldritchAbomination The Almagam]], who takes his place as the final boss]].
92** ''VideoGame/AtelierIris2TheAzothOfDestiny'': Chaos is one of the three Imperial Champions and seeks to [[spoiler:revive his dead sister. However, it turns out that he's an UnwittingPawn to the Crimson Azoth/Palaxius, an EvilSorceror who wants Lilith's power of creation and destruction for himself]].
93** ''VideoGame/AtelierIris3GrandPhantasm'': Crowley, once an unassuming raider, came into possession of the Shadow Gem, which granted him powers over darkness. [[spoiler:However, it's revealed that he's been possessed by an unnamed evil alchemist inhabiting said gem, and by Chapter 7, he is defeated and killed by the heroes, leaving the GreaterScopeVillain Uroborus to be the last threat they face]].
94** ''VideoGame/AtelierRoronaTheAlchemistOfArland'': Meredith Alcock is the Minister of Arland who issued the order to close down Rorona's workshop so that he can build a factory in its place. Once it becomes apparent that Rorona is passing the king's assigned tests, he becomes frustrated and starts sabotaging her efforts directly and indirectly, though most of his attempts are foiled by Rorona's mentor Astrid.
95* ''VideoGame/AzureDreams'': Beldo, the one responsible for the disappearance of Guy. He intends to use the [[OlympusMons monster born from the Ultimate Egg]] for his own selfish interests.
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99* ''VideoGame/BalanWonderworld'': Lance serves as the primary antagonist, being the source of the Nega Tones plaguing the dream worlds and transforming people in despair into monsters.
100%%* The ''VideoGame/BaldursGate'' series:
101%%** Sarevok Anchev in the first game.
102%%** Jon Irenicus in the second game.
103%%** Amelissan the Blackhearted in the ''Throne of Bhaal'' expansion to the second game and the last part of the story.
104%%** For the series as a whole, Bhaal might count, but in each individual installment he's the GreaterScopeVillain.
105* The ''VideoGame/BanjoKazooie'' series has Gruntilda, a classic WickedWitch. In the first game, she kidnaps [[DamselInDistress Tootie]] to steal her beauty for herself, and in subsequent games she plots vengeance against the titular bear and bird for thwarting her.
106* ''VideoGame/{{Battlefield}}'':
107** ''VideoGame/Battlefield3'': [[ManipulativeBastard Solomon]], who works to cause a war between the U.S. and Russia.
108** ''VideoGame/Battlefield4'': Admiral Chang, being the one leading the aggressive parts of the Chinese military you deal with.
109** ''VideoGame/BattlefieldHardline'': [[spoiler:[[DirtyCop Captain Julian Dawes]]]], who pits the different cartels and gangs against each other in order to take over as the new kingpin of Miami.
110** ''VideoGame/Battlefield1'': [[BaldOfEvil Tilkici]] is one to war story "Nothing Is Written" and the only notable "bad guy" in the entire anthology.
111** ''VideoGame/BattlefieldV'': [[ThoseWackyNazis Schröder]] is this for "The Last Tiger," due to his fanatical beliefs conflicting with the rest of his tank crew-mates' and even places them in danger with his actions as the tank's gunner.
112* ''VideoGame/BattleForWesnoth'': Most campaigns have one.
113** ''A Tale of Two Brothers'' has Talrach, the orcish warlord who forces necromancers Mordak and Rotharik to kidnap Baran.
114** ''An Orcish Incursion'' has Rualsha, the leader of the orcish army who are attacking the elves.
115** ''The South Guard'': The Urza brothers at first, who [[spoiler:has kidnapped Mebrin and forced him]] to raise undead for them to use in their raids in the southern Wesnoth. However when the heroes meet the last brother, [[spoiler:he reveals that Mebrin has gone insane, attacked the bandits, controlled the undead himself and supplanted them as the Big Bad]].
116** ''Heir to the Throne'': [[GodSaveUsFromTheQueen Queen Asheivere]]. The journey begins when she starts sending orcs after Konrad and Delfador. At the same time, Delfador wants to depose her and make Konrad the king.
117** ''Legend of Wesmere'': Great Chief Brubar, the leader of the orcish army attacking the elves, for the first four chapter. [[spoiler:[[HeelFaceTurn Landar]], who murders the elvish council and leads the xenophobic elvish side against Kalenz's,]] for the last one.
118** ''Eastern Invasion'': Mal Ravanal, the necromancer leading the titular invasion against Wesnoth.
119** ''The Hammer of Thursagan'': Karrag, lord of Kal Kartha.
120** ''Son of the Black Eye'': Earl Lanbech. In a reversal, he's a human earl amassing an army to destroy the ''orcs''.
121** ''The Rise of Wesnoth'': Lich Lord Jevyan, who allied himself with the orcs to take over the Green Isle.
122** ''Northern Rebirth'': Rakshas, leader of the orcish army that the protagonists have to defeat.
123** ''Under the Burning Suns'': [[spoiler:Yechnagoth]] who disguises herself as [[spoiler:the elven goddess Eloh]] and cause Kaleh and his people into journeying through the desert with an end goal of making them her slaves.
124* ''VideoGame/BattleTanx: Global Assault'': Cassandra, an insane psychic who created the plague that killed most of the world's women.
125* ''VideoGame/{{Battletoads}}'':
126** Classic series: [[TheBaroness The Dark Queen]] kidnaps Pimple and Princess Angelica and is bent on conquering the galaxy.
127** 2020 reboot: [[JerkassGods Uto and Pia]] are the leaders of the Topians and the tyrannical rulers of the galaxy who steal the powers of the Dark Queen.
128* ''Bayonetta'' series:
129** ''VideoGame/{{Bayonetta}}'': [[spoiler:[[ArchnemesisDad Father Balder]], the [[CorruptCorporateExecutive CEO]] of the Ithavoll Group,]] is the mastermind behind the angelic invasion of Earth.
130** ''VideoGame/Bayonetta2'': [[spoiler:[[GodIsEvil Loptr]], who is revealed to be responsible for Balder becoming the villain of the first game via possession]].
131** ''VideoGame/Bayonetta3'': [[spoiler:The Singularity]] is the leader of the Homunculi, [[spoiler:who discovered the secrets of the multiverse and seeks to merge all the universes into one]].
132* ''Bear With Me'' series has both the Red Man, a mysterious serial killer in Paper City who pursues Amber and Ted in the first game; and SerialKiller [[spoiler:Lifty Workofsky]], the person responsible for the disappearances of all robots in Paper City, acting as a threat to Ted and Flint in the prequel ''The Lost Robots'', but in both instances they are a BigBadEnsemble to the following:
133** ''VideoGame/BearWithMe'': The [[AxCrazy Red Man]] alongside the [[CorruptPolitician Mayor Daniel Mills]] who both target Ted and Amber across Paper City, but he is a NonActionBigBad and Locke is the one [[DragonInChief who is a threat to Ted and Amber and is the one furthering Mills' cause]]. The Red Man pursues both of them throughout the entire game, while Mills sends the PCPD to pursue both of them and to kidnap Amber for his own purposes. The Red Man has the most influence to the story and is the ArchEnemy to the protagonists, particularly Amber.
134** The prequel ''VideoGame/BearWithMeTheLostRobots'': [[spoiler:[[ManipulativeBitch Lifty Workofsky]]]] alongside [[CorruptCorporateExecutive Smiley G. Skinner]], who are both the enemies to Ted and Flint. Skinner is the corrupt CEO of Illuminarium who is responsible for plunging the economy into hyperinflation by hoarding several ratchet relays for his own purposes, as well as him being complicit in the relay shortage; [[spoiler:Lifty is the seemingly blunt but well-meaning head of Paper City's Robot Union who is later revealed to be EvilAllAlong, being responsible for the mass-disappearances of the robots across the city]].
135* ''VideoGame/TheBeginnersGuide'': InUniverse, [[spoiler:The Machine]] gradually becomes the main threat in Coda's games, as it is warping the game worlds in destructive ways. [[spoiler:However, it is implied to merely be TheScapegoat for the protagonist. Out of universe, [[AuthorAvatar Davey Wreden himself]] turns out to have been responsible for Coda's disappearance, as his tampering with Coda's games drove him away.]]
136* ''VideoGame/BeingOne'': [[MadScientist Dr. Rycroft]] [[BigBadDuumvirate and]] his shady employer, [[CorruptCorporateExecutive Weston Carnodyne]], are behind countless unethical experiments to [[ImmortalityImmorality find the secret to immortality]].
137* ''VideoGame/BendyAndTheInkMachine'' has the Ink Demon, a monstrous ink creature based on the titular InUniverse cartoon character.
138** ''VideoGame/BorisAndTheDarkSurvival'' has the Ink Demon again.
139** ''VideoGame/BendyAndTheDarkRevival'' has a BigBadEnsemble between the Ink Demon once more, only this time he's unambiguously malevolent and intelligent, and Wilson, a man who took control of the Ink Machine and seeks to usurp the Ink Demon as ruler of the [[spoiler:Cycle]].
140* ''VideoGame/BevelsPainting'': The [[EvilDoppelganger other Bevel]] is Bevel's main obstacle in escaping the painting who seeks to kill her and keep her trapped. Exactly why, and what she is, [[MindScrew is unclear]].
141* ''VideoGame/BeyondGoodAndEvil'': [[EvilOverlord General Kehck]] is the Supreme Commander of the Alpha Section of the planet Hyllis who oppresses the people under the guise of protecting them from the [[AlienInvasion DomZ invasion]] and is the primary enemy of [[TheHeroine Jade]], who seeks to overthrow him. [[spoiler:[[DiscOneFinalBoss Except]] he is secretly [[LesCollaborateurs working for]] the [=DomZ=] High Priest, who leads the [=DomZ=] aliens that have been invading Hylis, has drained countless planets to keep himself alive, and secretly controls the Alpha Sections.]]
142* ''VideoGame/BeyondTwoSouls'': [[spoiler:[[BigBadSlippage Nathan Dawkins]], who aims to merge the Infraworld with the human world so he may reunite with his departed family, which would result in TheEndOfTheWorldAsWeKnowIt]].
143* ''VideoGame/BinkyShow'': Binky is the MonsterClown trying to kill the PlayerCharacter.
144* ''VideoGame/BioShock'':
145** ''VideoGame/BioShock1'': [[ItsAllAboutMe Andrew Ryan]] [[BigBadEnsemble and]] [[spoiler:[[TreacherousQuestGiver Frank Fontaine]]]]. Andrew Ryan being the creator of Rapture and the leader of the splicers, and [[spoiler:Fontaine]], who began the cataclysmic civil war [[spoiler:and uses Jack to take over Rapture]].
146** ''VideoGame/BioShock2'': [[TotalitarianUtilitarian Sophia Lamb]], who aims to use her daughter [[ApocalypseMaiden Elanor]] to take control of Rapture and destroy the concept of individuality itself.
147** ''VideoGame/BioShockInfinite'': [[DarkMessiah Zachary Hale Comstock]], who created Columbia and plans to make Elizabeth into his successor and destroy the world below.
148* ''VideoGame/BionicCommando1988'' has [[TheGeneralissimo Generalissimo Killt]] [[spoiler: until Master-D comes BackFromTheDead and promptly kills Killt, before declaring his intention to TakeOverTheWorld himself]].
149* ''VideoGame/BitTrip'': Mingrawn Timbletot is the ArchEnemy of [=CommanderVideo=] that repeatedly tries to kill him.
150* ''VideoGame/BlackDaliah'': [[spoiler:Richard "Dick" Winslow, a Nazi operative who desires the [[MacGuffin Black Daliah gem]] so he can use it to rule the United States as a new Reich]].
151* ''VideoGame/TheBlackHeart'': [[EvilOverlord Janos]], the Prince of the Other World, who launched the war of two worlds in his quest to obtain the Black Heart and gain ultimate power.
152* ''VideoGame/BlankDream'': [[spoiler:Utsuro Hinohara]] is the creator of the Mirror World and aims to kill Mishiro Usui to [[spoiler:gain back control of it]].
153* ''VideoGame/{{Blasphemous}}'':
154** First game: [[SinisterMinister His Holiness Escribar]], the head of the theocracy ruling Cvstodia responsible for the massacre of the Brotherhood of the Silent Sorrow that kickstarts the Penitent One's quest.
155** ''VideoGame/BlasphemousII'': [[MagicKnight Eviterno]], the leader of the Archconfraternity seeking to resurrect [[GreaterScopeVillain the High Wills]] and unleash the Grievous Miracle back upon the world once more.
156* ''VideoGame/BlazingSoulsAccelate'': [[AGodAmI Gustavinus]], the leader of the Human Genomes who intends on replacing Men and Demons with Genomes using the power of [[PhysicalGod Mugen]].
157** ''VideoGame/BlightDream'': The SerialKiller who murdered two people at Mashiba Hospital and is now coming after Michiru. [[spoiler:Except that [[TomatoInTheMirror Michiru herself]] is the [[TheKillerInMe amnesiac]] serial killer.]]
158* ''VideoGame/ABlindLegend'' has the king who has Edward's daughter captured by some of his guards.
159* ''Franchise/BlazBlue'' has a BigBadDuumvirate of [[Characters/BlazblueYuukiTerumi Yuuki Terumi]], [[MadScientist Relius Clover]] and [[FauxAffablyEvil Hades Izanami]], the [[EverybodyHatesHades Goddess of Death]]. It's not an exaggeration to say every tragedy in the series was orchestrated or caused by some combinations of their plans. [[spoiler:Although in the end it's Terumi who claims the mantle of ultimate villain of the series once he takes back his original body, the [[AnimatedArmor Susanoo Unit]], from Hakumen, and becomes his true self: [[SatanicArchetype Susanoo]], the god of destruction, the brother of [[GreaterScopeParagon Amaterasu]], and the FinalBoss and undisputed BigBad of the entire series.]]
160* ''VideoGame/BleedingSun'': Ichiro is the main antagonist who killed Akio Takenaka in order to claim the latter's territory and rule over it with an iron fist. He also enables the WickedWitch, Chiyo, to turn people into zombified slaves to further cement his rule.
161* ''VideoGame/BloodRayne'': [[ThoseWackyNazis Jurgen Wulf]] is the supreme commander of the [[{{Ghostapo}} Gegengeist Gruppe]] who intends to assemble the pieces of [[GreaterScopeVillain Beliar]] to sustain the power of the Third Reich.
162** ''VideoGame/BloodRayne2'': [[VampireMonarch Kagan]] is the ArchnemesisDad of the titular heroine who desires to TakeOverTheWorld and assert the supremacy of vampires over humanity.
163* ''VideoGame/BloodstainedRitualOfTheNight'': [[spoiler:[[BitchInSheepsClothing Dominique Baldwin]], who seeks to summon [[EldritchAbomination Bael]] and have his demonic forces consume the world so she can obtain the power to kill God]].
164* ''VideoGame/BlueDragon'':
165** The first game has Nene, an Ancient bent on plunging the world into grief. [[spoiler:At least, up until the end of the game; then it's revealed to actually be his sidekick Deathroy, who is actually the Ancient ultimate bioweapon Destroy.]]
166** The second game has Balaur, an evil three-headed dragon Shadow that lives within the Atomic Cube and is wielded [[spoiler:by Nene's evil side, both of whom are the end result of energy stored in the Atomic Cube]].
167** The third game has Jyum and Ganda, who are [[spoiler:of the same race as Nene. At first it seems like their goal is stop Nene from taking over the world. However this turns out to be a lie and their actual goal is use the Egg of Light to create a new planet to rule over as gods. To this end, they use you by sending you off to grow stronger so that they could drain your shadow, believing that it would be strong enough to create a new planet. After their defeat, the Egg of Light becomes the final antagonist and goes on a rampage, requiring you to travel across planets and eventually defeat your dark self sealed in the Box of Ordeals in order to grant your shadow enough power to prevent the Egg of Light from devouring your planet]].
168* ''VideoGame/BlueSkiesSeries'':
169** ''VideoGame/BlueSkies'': Lord Gwir is the ruler of Xmeil, who seeks to conquer the planet of Vyen, kill anyone who opposes him, and convert the survivors into mutants to expand his army. However, [[spoiler:he's an UnwittingPawn for the Celestial Cael, who wants to use Gwir's war to weaken humanity. After Cael kills Gwir, he goes to his own fortress in orbit so that he can use his magic to wipe out the rest of humanity from afar]].
170** ''VideoGame/BlueSkies2'': Rhetz is the current leader of the Holy Order of Vyena, an organization that claims to protect the world's peace by hunting down mages. However, he secretly [[spoiler:sacrifices mages in order to absorb their power for his own use. He later uses the rest of the mage prisoners as hostages to force Lyrelle's party to get the Holy Stone for him, which he uses to gain divine power in the hopes of becoming Vyena's champion and forcing order on the world. He turns out to be manipulated by Matria, who wants to use his new divine power to give birth to Scion the Devourer of Worlds, all so she can destroy and remake Vyen in her own image]].
171** ''VideoGame/HeroesOfTheSeasons'': Goblin King Frinch hates Christmas and attacks Utania Village with his army of like-minded minions in order to stop their celebrations. Unfortunately, he's overshadowed by his henchman, Gobi, who uses his connections to call upon stronger Christmas-hating villains when Frinch proves too incompetent for the task. In the final stage, [[spoiler:Gobi himself subverts his NonActionBigBad status and becomes the FinalBoss]].
172* ''VideoGame/Bodycount2011'': [[NoNameGiven The Nemesis]], the leader of [[AncientConspiracy the Target]], is responsible for destroying most of [[WeHelpTheHelpless the Network]] and orchestrating various worldwide conflicts resulting in the deaths of millions. She also tries to murder the protagonist and his MissionControl ally to fully eradicate what's left of the Network.
173* ''VideoGame/{{Bomberman}}'''s ArchEnemy and series villain is [[EmperorScientist Professor Bagura]], who is always trying to conquer and/or destroy as much of the universe as he can through his various schemes.
174** ''VideoGame/BombermanII'': Black Bomberman frames White Bomberman for a robbery he committed, so Bomberman must pursue him to [[ClearMyName clear his name]].
175** ''Bomberman 1990'': Black Bomberman kidnaps Lisa Mitsumori, and White Bomberman has to save her.
176** ''VideoGame/Bomberman93'': Black Bomberman shuts down the pan-galactic bureau [[MasterComputer mother computer]] by stealing the seven chips and scattering them across the Magellan solar system.
177** ''VideoGame/Bomberman94'': Buglear debuts here, invading Planet Bomber with his robot army and splitting it into five pieces in order to destroy it.
178** ''VideoGame/SuperBomberman'' series:
179*** Original game: Carat Diamond holds the Robot Tournament as part of his scheme to steal Bomberman's advanced battle capabilities.
180*** ''Super Bomberman 2'': Plasma Bomber is the leader of the Five Dastardly Bombers who kidnaps White Bomberman and intends to conquer the universe.
181*** ''Super Bomberman 3'': Bagular returns and revives the Five Dastardly Bombers and sends them out to destroy Bomberman.
182*** ''Super Bomberman 4'': Bagular summons the Four Bomber Kings and Great Bomber to get revenge on White and Black Bomberman.
183*** ''Super Bomberman 5'': Emperor Terrorin frees various criminal Bombers and causes havoc in Planet Bomber.
184*** ''Super Bomberman R'': Emperor Buggler resurrects the Five Dastardly Bombers and sets out to conquer the galaxy.
185** ''Bomberman GB 3'': Evil Bomber, an abandoned creation of Bagura, escapes his imprisonment on Planet Owen and conquers it, stealing all the Bomber Capsules to deprive Bomberman of his strength.
186** ''VideoGame/SaturnBomberman'': [[HoaxHogan Mujoe]], leader of the [[SpacePirates Hige Hige Bandits]], gains control of the monster Crator and intends to use it to TakeOverTheWorld.
187** ''Neo Bomberman'': Bagura crashes the Bomberman Tournament and kidnaps the combatants save White and Black Bomberman, who set out to rescue them.
188** ''VideoGame/Bomberman64'': Altair is the [[GalacticConqueror planet conqueror]] who, using the Omni-Cube, seeks to make Planet Bomber his next conquest. Getting all 100 Gold Cards reveals that Altair [[spoiler:[[DiscOneFinalBoss actually]] stole the cube from Sirius, [[TreacherousAdvisor supposedly an ally]] but really a conqueror himself who decides to destroy Planet Bomber after killing Altair]].
189** ''VideoGame/Bomberman64TheSecondAttack'': Rukifellth is the leader of the Black Hole Bomber Army who aims to collect all the Elemental Stones and consume the entire universe in his black hole, [[spoiler:except the actual villains are the God of Darkness Stherthoth, who is possessing him, and the Goddess of Light Mihaele, who aims to [[OmnicidalManiac destroy the universe]] so a perfect new one can be made- both are fragments of the Angel of Light and Shadow, who becomes the TrueFinalBoss]].
190** ''VideoGame/BombermanWorld'': Buggler releases the Dark Force Bombers and sends them to conquer four worlds.
191** ''VideoGame/BombermanHero'': [[spoiler:Evil Bomber]] is the acting ruler of the Garaden Empire who masterminds the kidnapping of Princess Millian and the plot to [[spoiler:resurrect Emperor Bagular]], all to get revenge on Bomberman for defeating him prior.
192** ''Bomberman Quest'': Chaos Bomber is the leader of the Four Commanders who steal the engines of Bomberman's shuttle and let loose all the monsters.
193** ''VideoGame/BombermanMax'': [[AIIsACrapshoot Brain]] has turned five planets into dark, mechanical worlds and is endangering the Charabom who live there.
194** ''VideoGame/BombermanTournament'': Brain Bomber leads the Five Dastardly Bombers who take over planet Phantarion and kidnap MAX.
195** ''Bomberman Max 2'': Mujoe has shrunk Bomberman and MAX to mini-size with his Mini-Mini Device.
196** ''VideoGame/BombermanGeneration'': Mujoe, in another plot of galactic conquest, destroys the freighter containing the six Bomb Elements, scattering them across Planet Tentacalls, and sends the Crush Bombers to collect them.
197** ''VideoGame/BombermanJetters'': Mujoe, after his defeat in ''Generation'', attempts to crash his artificial comet, the Dark Star, into Planet Bomber and kill everyone on it to get revenge on Bomberman for good.
198** ''Bomberman Story DS'': Professor Xeal has stolen some scientific data that White Bomberman is charged with getting back.
199* ''VideoGame/BonniesBakery'': Bonnie herself is actually a SerialKiller who kidnaps the talking animals to turn them into her ingredients, and plans to make the true protagonist her next victim.
200* ''VideoGame/TheBoogieMan'': The [[AntagonistTitle titular]] Boogie Man is the one who hijacks the tour of Livingstone Castle to force Keith into a DeadlyGame where he must explore the castle to save the other tourists from various {{Death Trap}}s. [[spoiler:However, this Boogie Man is actually Brendon Dumont, the castle owner and host of the tour, who is pretending to be the real Boogie Man.]]
201* ''VideoGame/{{Borderlands}}'':
202** ''VideoGame/Borderlands1'' has [[TheBaroness Commandant Helga Steele]], the leader of the Crimson Lance, dedicated to finding and plundering the Vault first.
203** ''VideoGame/Borderlands2'' has [[CorruptCorporateExecutive Handsome Jack]], whose plans to "cleanse" Pandora by eliminating its undesirables act as the driving force of the plot.
204** ''VideoGame/BorderlandsThePreSequel'' has [[WellIntentionedExtremist Colonel Tungsteena Zarpedon]] as the main villain for most of the game, [[spoiler:though she's defeated in the penultimate main mission]].
205** ''VideoGame/TalesFromTheBorderlands'' has [[TheQueenpin Vallory]], being behind all of the forces aligned against Fiona and Rhys.
206** ''VideoGame/Borderlands3'' has [[SiblingTeam Tyreen and Troy Calypso]], the leaders of the Child of the Vault who seek the power of the Vaults, with [[AGodAmI Tyreen]] being the dominant partner.
207** ''Videogame/TinyTinasWonderlands'' has the Dragon Lord, who is Tina's go-to BBEG for her RPG campaigns who has somehow managed to achieve some level of sentience and fights the player (and by proxy Tina) for control over his own fate and not be subject to the whims of a 13 year old.
208* ''VideoGame/BotGaiden'': The villain of the game is the mysterious Giorquo, who is having his hench-bots power themselves up with golden skulls.
209* ''VideoGame/{{Braid}}'': The monster that kidnapped the Princess. [[spoiler:The menacing-looking knight in the final level is in fact ''rescuing'' the DamselInDistress from [[VillainProtagonist Tim himself]].]]
210* ''VideoGame/BravelyDefault'':
211** Original game: [[TinTyrant Braev Lee]] is the templar and Grand Marshall of [[TheEmpire the Duchy of Eternia]] who wants to TakeOverTheWorld and stop [[TheHero Agnès]] and her party from awakening the four crystals that will stop TheCorruption from spreading; his goals in doing this [[HiddenAgendaVillain are a mystery]]. A secondary threat also exists in the [[HiddenVillain “Evil One”]], an unknown presence who apparently wants to spread the corruption and may have a connection to Eternia, but they are mainly in the background, [[spoiler:until it turns out [[DiscOneFinalBoss Brav Lee]] was [[GoodAllAlong trying to stop]] the Evil One; [[UnwittingPawn everything Agnès did is actually part of a plan concocted by]] the Evil One, AKA [[FairyCompanion Airy]] [[EvilAllAlong the Fairy]], to awaken the Crystals and create links to alternate worlds for [[GreaterScopeVillain her father]], {{Ouroboros}} the {{God|OfEvil}} of Destruction, to enter and conquer the Celestial Realm]].
212** ''VideoGame/BravelySecond'': [[TheEmperor Kaiser Oblivion]], the ruler of the [[TheEmpire Glanz Empire]], is the [[SaveThePrincess kidnapper of Agnès]] and wants to use her for his [[HiddenAgendaVillain plan]] to [[spoiler:[[WellIntentionedExtremist rewrite the past for a better future and erase his bloodline from existence]]. [[DiscOneFinalBoss Except]] he has been manipulated by [[FairyCompanion Anne the Fairy]] into constructing the Holy Pillar so she can get rid of the moon, then re-open the link to the Celestial Realm to allow [[GreaterScopeVillain her own master]] and [[GodIsEvil ruler of the Celestial Realm]], Lord Providence, to invade, while revealing that she only assisted in the defeat of Airy and Ouroboros in the first game in order to remove a threat to Providence so that he/{{she|sAManInJapan}} may [[EmotionEater feast on the world’s despair]]]].
213** ''VideoGame/BravelyDefaultII'': Adam is the Lord Commander of [[TheEmpire Holograd]] who destroyed Gloria's kingdom to gather the crystals and TakeOverTheWorld to bring an end to all wars. [[spoiler:In truth, he is being manipulated by his right-hand woman Edna, who seeks to awaken the [[GreaterScopeVillain Night's Nexus]] and destroy everything due to her hatred of humans, having given people the Asterisks not only to drain the power of the crystals, but to ensure that the Nexus could never be defeated.]]
214* ''VideoGame/{{Breakdown}}'': [[AIIsACrapshoot Nexus]], the alien AI leading the T'lan in destroying humanity.
215* ''VideoGame/BrokTheInvestiGator'': Prototype-26, or rather [[spoiler:Wes]], is the one trying to [[KillThePoor eradicate all of the Slumers]] by causing a Pipe-Pill shortage and manipulating the government into executing all prisoners since he believes criminals (and Slumers as a whole) are incapable of being reformed.
216* ''VideoGame/BrutalLegend'': Lord Doviculus for the main story. He's the leader of the Tainted Coil, is responsible for Lionwhyte's domination of humanity and the Drowning Doom's resurgence as a faction, and the main target of the rebellion.
217* ''VideoGame/{{Bubbaruka}}'': [[spoiler:The Creature]] is the entity behind the predators that stalk the titular Bubbaruka pets, and the one behind the mysterious disappearance of the game developers.
218* ''VideoGame/Buddy2020'': The titular [[AIIsACrapshoot Buddy V2.1]] is the one who abducted the player and wants to keep them trapped inside the room to kill them.
219* ''VideoGame/BuddySimulator1984'': The antagonist of the InUniverse game is the Snoodlewonker, a massive serpent-wyrm that has massacred at least half a town and is threatening Mayor Tortley and his village. The second half of the game revolves around rescuing Mayor Tortley from its clutches. [[spoiler:Ultimately, however, the real villain is [[AIIsACrapshoot the titular Buddy]], who not only programmed the Snoodlewonker (and the rest of the game), but tries to destroy every NPC that comes between them and you while turning into a controlling ToxicFriendInfluence so [[{{Yandere}} they can play with you forever]].]]
220* ''VideoGame/BugFables'': The [[WickedWasps Wasp King]] is the EvilOverlord of the militaristic Wasp Kingdom who seeks the [[FountainOfYouth Everlasting Sapling]] so he can become immortal and [[TakeOverTheWorld conquer Bugaria]]. [[spoiler:The post-game reveals that he isn't even a wasp, but a wasp-mimic fly named Hoaxe who usurped the rightful Queen.]]
221* ''VideoGame/{{Bulletstorm}}'': [[GeneralRipper General Victor Sarrano]], the general of the Confederate Army tasked with wiping out Stygia with a [=DNA=] bomb.
222* ''VideoGame/{{Bully}}'': [[TheSociopath Gary Smith]], who manipulates the main character Jimmy Hopkins and the cliques against each other in order to become the ruler of Bullworth Academy.
223[[/folder]]
224
225[[folder:C]]
226* ''VideoGame/CTwelveFinalResistance'': The Alien Leader, who's controlling the alien army and serves as the game's FinalBoss.
227* ''VideoGame/CafeVenusFlytrap'': [[EvilChef The chef frog]], being directly responsible for killing and serving the sapient insects and animals as meals for Harvest Day, as well as the titular fly's primary pursuer.
228* ''VideoGame/CallOfDuty'':
229** ''VideoGame/CallOfDutyModernWarfare2'': At first you think it's Vladimir Makarov, ascendant leader of the Ultranationalists, but it turns out to be [[spoiler:General Shepherd, an insane rogue general]].
230** ''VideoGame/CallofDutyInfiniteWarfare'': Admiral Salen Kotch, leader of the Settlement Defense Front.
231** ''VideoGame/CallOfDutyWWII'': Heinrich, an SS officer stationed in German-occupied France, seemed like this for the main campaign but he's actually a DiscOneFinalBoss. Metz, an SS officer handling [=POW=]s, would be the closest to this as he's the FinalBoss before the campaign officially ends.
232** ''VideoGame/CallOfDutyVanguard'' has Hermann Freisinger, a Gestapo officer in charge of Project Phoenix.
233** ''VideoGame/CallOfDutyZombies'':
234*** The "Aether" Story starts with [[CreepyChild Samantha Maxis]] in charge of the zombies, before the [[MadScientist Ultimis version of Edward Richtofen]] takes control of the zombies, but he is then revealed to be in a BigBadEnsemble with fellow scientist [[NecessarilyEvil Dr. Ludvig Maxis]], and [[spoiler:[[EldritchAbomination the Apothicons, represented by the Shadow Man]] are eventually revealed to be the real threat behind the zombies, attempting to invade and destroy the multiverse. After they are defeated, however, [[BigGood Dr. Monty]] is shown to be EvilAllAlong and having been in a BigBadEnsemble with the Apothicons, hoping to perpetuate the zombie-infested StableTimeLoop to keep himself in power]].
235*** The "Chaos" Story has the High Priest of Chaos, leader of the Order, [[spoiler:[[BigBadEnsemble and]] the Oracle of Delphi/Medusa]].
236** ''VideoGame/CallOfDutyGhosts'': Gabriel Rorke, the [[BrainwashedAndCrazy brainwashed]] former leader of the Ghosts, now the top agent of the Federation. The current leader of the Federation appears to be a GreaterScopeVillain of sorts. He's never seen or referred to by name, but Rorke seems to hold him in great respect.
237** ''VideoGame/CallOfDutyAdvancedWarfare'': Joseph "Hades" Chkheidze, leader of the KVA terrorist group [[spoiler:who is ultimately a DiscOneFinalBoss used by Jonathan Irons, the CEO of Atlas Corporation and the real BigBad]].
238** ''VideoGame/CallOfDutyModernWarfare2019'': Omar "The Wolf" Sulaman, the leader of Al-Qatala, [[BigBadEnsemble and]] General Roman Barkov, a rogue Russian general. [[spoiler: "The Wolf" is ultimately a DiscOneFinalBoss, and the rest of the campaign focuses on stopping separate threats from Barkov and "The Butcher", [[TheDragon the lieutenant]] of "The Wolf" who is working with [[WellIntentionedExtremist Hadir Karim]]]].
239%%** ''VideoGame/CallOfDuty1'', ''VideoGame/CallOfDuty2'', and ''Call of Duty 3'' have ThoseWackyNazis in general.
240%%** ''VideoGame/CallOfDuty4ModernWarfare'': Imran Zakhaev, leader of the Ultranationalists.
241%%** ''VideoGame/CallOfDutyModernWarfare3'': Vladimir Makarov's the real deal this time around, still leading the Ultranantionalists.
242%%** ''Black Ops'' sub-series:
243%%*** ''VideoGame/CallOfDutyWorldAtWar'': ThoseWackyNazis again.
244%%*** ''VideoGame/CallOfDutyBlackOps'': Nikita Dragovich, a sadistic Soviet General.
245%%*** ''VideoGame/CallOfDutyBlackOpsII'': Raul Menendez, a Nicaraguan terrorist leader.
246%%*** ''VideoGame/CallOfDutyBlackOpsIII'': [[spoiler:Corvus, an insane AI.]]
247%%*** ''VideoGame/CallOfDutyBlackOps4'': [[spoiler:Savannah Mason-Meyers, a businesswoman trying to resurrect dead soldiers as part of Project Blackout.]]
248%%*** ''VideoGame/CallOfDutyBlackOpsColdWar'': Perseus, a rogue Soviet espionage ringleader.
249%%** Dr. Peter Straub serves as this for the ''VideoGame/CallOfDutyWWII'' [[VideoGame/CallOfDutyZombies Nazi Zombies]] campaign.
250* ''VideoGame/CallOfJuarez'': The titular Juan "Juarez" Mendoza, a Mexican bandit turned warlord who Billy and Ray are after.
251** ''[[VideoGame/CallOfJuarezBoundInBlood Bound In Blood]]'': Jeremy Barnsby, a Confederate commander who runs a gun-running operation in the hopes of putting together enough money to finance a second rebellion.
252** ''[[VideoGame/CallOfJuarezTheCartel The Cartel]]'': Cartel leader Juan Mendoza (Mind you not the same character in the first two games) and CorruptCorporateExecutive Michael Duke, [[spoiler: as well as Assistant Deputy Director Shane Dickson acting as Mendoza's partner inside the Justice Department]], and Psycho for Hire Antonio Alvarez playing all sides against each other for his own advantage.
253%%** ''[[VideoGame/CallOfJuarezGunslinger Gunslinger]]'': Roscoe Bryant.
254* ''VideoGame/CandyMountainMassacre'': The Cake Queen, who is responsible for the virus that turned everyone evil.
255* ''VideoGame/CannonDancer'' features Jack Layzon as the primary antagonist who used and betrayed the main character, Kirin, for his own needs. [[spoiler:[[GreaterScopeVillain The mysterious goddess Slaver]], however, uses Kirin's revenge as a way to enslave him to her will, and ends up becoming the FinalBoss for her troubles.]]
256* ''VideoGame/CapellasPromise'': The previous king of Ilnacia, who built the Mother superweapon to convert his citizens into monstrous soldiers. [[spoiler:However, he's eventually killed by [[TheEvilPrince his son, Prince Zanara Capella]], who takes over as king and fuses with the Mother.]]
257* ''VideoGame/CaptainCommando'' has Scumocide ([[NamesToRunAwayFromReallyFast Genocide]] in Japanese), the leader of a genetically-enhanced breed of "Super Criminals" terrorizing Earth.
258* ''VideoGame/CaptiveRPGMaker'': [[HiddenVillain The captor]] who kidnapped the protagonist and several others and is holding them inside the basement complex. The endings reveal it to be [[spoiler:[[TheKillerInMe the amnesiac protagonist herself]], who did everything to find a cure for her father, who came down with an unknown illness]].
259* ''VideoGame/CardinalSyn'': The titular Syn is the woman running the bloody tournament between the clans of the Bloodlands.
260* ''VideoGame/CarnEvil'': Professor Ludwig von Tökkentäkker, the creator and head of the titular [=CarnEvil=] that the players must fight through.
261* ''VideoGame/Case02ParanormalEvil'': Gla'aki is leading a zombie apocalypse cult to ravage a hospital and later the rest of the world. She also plans to use Sally's body to gain a physical form.
262* ''VideoGame/CastleRed'': The Lord of Castle Red, aka [[spoiler:[[TreacherousAdvisor Howard]]]], wants to sacrifice the trapped visitors to the [[GreaterScopeVillain godlike worms]] in exchange for more power.
263* {{Dracula}} in almost every ''Franchise/{{Castlevania}}'' game. The Japanese title is ''Demon Castle Dracula'' for a reason. However, there are games where he either doesn't appear, or is out of the picture until [[FinalBoss the very last boss fight]], making him more of a GreaterScopeVillain with others filling the BigBad role:
264** In ''VideoGame/CastlevaniaBloodlines'', the villain is Dracula's niece [[UsefulNotes/ElizabethBathory Elizabeth Bartley]], who leads a campaign of evil across Europe to resurrect her uncle.
265*** ''VideoGame/CastlevaniaPortraitOfRuin'', a direct sequel to ''Bloodlines'', sees the power of Dracula's castle commandeered by [[MadArtist Brauner]], who uses his [[ArtInitiatesLife magical paintings]] to cut off the throne room from the castle's magic so that Dracula cannot be resurrected, and plans to create a painting that would bring about TheEndOfTheWorldAsWeKnowIt. The heroes spend most of the story opposing his forces while also confronting Death, who is not happy about the situation and wants Dracula back.
266** In ''VideoGame/CastlevaniaSymphonyOfTheNight'', the apparent villain is [[spoiler:Richter Belmont]], but it's more complicated than that; [[spoiler: Shaft is TheManBehindTheMan controlling Richter, and the active force behind Dracula's resurrection]].
267** In ''VideoGame/Castlevania64'', Dracula does indeed show up very early on, [[spoiler:except that this is merely a fake, and is actually Dracula's servant UsefulNotes/GillesDeRais in disguise. Instead, the true villain is [[CreepyChild Malus]], the true reincarnation of Dracula who assumes his true form if the heroes manage to reach the final stage [[TimedMission in time for the good ending route]].]]
268** ''64'''s UpdatedRerelease ''VideoGame/CastlevaniaLegacyOfDarkness'' introduces the story of Cornell, set eight years before Dracula's resurrection in the main game, whereupon he is antagonized by his personal nemesis [[TheResenter Ortega]], who has [[VillainTeamUp joined up]] with Dracula's current group of crony generals— Death, Gilles de Rais, and Actrise.
269** Dracula is once again initially absent in ''VideoGame/CastlevaniaHarmonyOfDissonance'' despite the re-emergence of his castle. Death is present from the start, but is also confused at the absence of his master. It turns out that the active main villain for most of the game is [[spoiler:an [[EnemyWithin evil alternate personality]] of protagonist Juste's friend Maxim Kischine, created by his feelings of jealousy and hatred allowing Dracula's spirit to begin taking control of his psyche. In the best ending route, Dracula's spirit abandons Maxim upon defeat to inhabit [[PlotCoupon his own bodily remains]], taking on a Wraith form that enables him to initiate a TrueFinalBoss encounter]].
270** ''VideoGame/CastlevaniaLamentOfInnocence'', serving as something of an OriginsEpisode for the series, does not yet feature Dracula, but instead has its main villain in his predecessor, the vampire lord Walter Bernhard. The entire game leads up to a confrontation with him, [[spoiler:after which his servant Death betrays him, allowing [[BigBadFriend Mathias Cronqvist]] to capture his vampiric soul in the [[SoulJar Crimson Stone]], which he would use to become Dracula, while Death is fought as the FinalBoss.]]
271** ''VideoGame/CastlevaniaCurseOfDarkness'' has Devil Forgemaster Isaac, who leads a legion of monsters in order to force Hector to take up his demonic powers once more. He succeeds in pitting Hector and Trevor Belmont against each other in a bid to raise Dracula's castle, though ultimately the true villain of the story is [[spoiler:Death, in disguise as the monk [[SdrawkcabName Zead]], who meant for Hector to kill Isaac and succumb to the curse, becoming the perfect vessel for Dracula's resurrection. When Hector defies this, Death ends up using Isaac as a lesser vessel to resurrect Dracula]].
272** In ''VideoGame/CastlevaniaAriaOfSorrow'', the BigBad is the {{Cult}} leader and self-proclaimed [[TheAntichrist Antichrist]], Graham Jones. [[spoiler:At least until TheReveal, at which point it turns out that ''you'' are the actual [[TheAntichrist Antichrist]], prompting a crazy TrueFinalBoss battle against [[EnemyWithin Dracula's power trying to take you over from within]].]] ''Dawn of Sorrow'' continues the story by splitting Graham's role between Celia Fortner, who leads a cult (possibly the same as Graham's), and the two Dark Lord Candidates [[PlayingWithFire Dario Bossi]] and [[PowerCopying Dmitrii Blinov]]. In the end, [[spoiler:Dario is stripped of his powers and flees, and Dmitrii copies Soma's Power of Dominance and sacrifices Celia to strengthen it. This [[EvilIsNotAToy doesn't work out]], and the souls of the demons he absorbed end up manifesting as [[EldritchAbomination Menace]], who serves as the FinalBoss… unless you're playing Julius Mode, in which Dmitrii never gets the chance because [[RogueProtagonist Soma Cruz]] beats him to the punch by killing Celia first and usurping her position]].
273** ''VideoGame/CastlevaniaOrderOfEcclesia'' begins with Dracula's sealed remains in the possession of [[MagicalSociety Ecclesia]], who are about to use a magical force called Dominus to conduct a ritual seemingly capable of neutralizing them once and for all. Unfortunately this ritual is interrupted by [[APupilOfMineUntilHeTurnedToEvil Albus]], who steals Dominus seemingly out of offense for not being chosen for the ritual, and must be pursued by protagonist Shanoa to get it back. [[spoiler:Except that Albus was GoodAllAlong and was trying to protect Shanoa from sacrificing her own life, which is what using Dominus, which was made from Dracula's own evil power, would entail... something that had been conveniently left unmentioned by [[TreacherousAdvisor Barlowe]], the head of Ecclesia, who never intended to destroy Dracula, but rather to unseal and resurrect him once more. In the end, Barlowe is able to sacrifice his own life to resurrect Dracula, who serves as the villain of the final act.]]
274** ''VideoGame/CastlevaniaLordsOfShadow'':
275*** The base game has the titular Lords of Shadow: Cornell of the werewolves, Carmilla of the vampires, and Death of the necromancers, whom Gabriel Belmont seeks to defeat in order to SaveTheWorld and claim the pieces of the [[MacGuffin God Mask]], which he believes can resurrect his wife Marie. Naturally, it gets more complicated than that: [[spoiler:The Lords of Shadow turn out to be the [[TheHeartless evil selves left behind]] when the three ancient sages that founded the Brotherhood of Light that Gabriel belongs to cast off their imperfect earthly forms in order to ascend as perfect spiritual beings, and Death's true identity is [[BigBadFriend Zobek]], who had been manipulating Gabriel in the guise of a wise advisor to bring him the other Lords' pieces of the God Mask, going so far as becoming the party responsible for Marie's death which he forced Gabriel to do by [[BrainwashedAndCrazy brainwashing him]] with the [[ArtifactOfDoom Devil Mask]], providing his main motivation. Then it turns out that Zobek had himself been manipulated by {{Satan}}, who desired the mask for his own ends and becomes Gabriel's [[FinalBoss final enemy]]]].
276*** The ''Reverie'' DLC has [[SealedEvilInACan The Forgotten One]], a tremendously powerful demon who threatens to come to Earth and cause TheEndOfTheWorldAsWeKnowIt as a result of [[NiceJobBreakingItHero Gabriel's actions in the base game.]] [[spoiler:It is in the process of entering the realm the demon is sealed in and destroying it that Gabriel gains the dark power that turns him into this timeline's version of Dracula.]]
277*** Dracula fulfills the BigBad role again in ''[[VideoGame/CastlevaniaLordsOfShadowMirrorOfFate Mirror of Fate]]'', but he becomes the protagonist in ''[[VideoGame/CastlevaniaLordsOfShadow2 Lords of Shadow 2]]'', where he reluctantly [[EnemyMine works together with]] [[spoiler:Zobek]] to oppose Satan's acolytes and prevent his resurrection.
278** Some spinoffs include this as well:
279*** ''VideoGame/KidDracula'' has Dracula's kid [[EpilepticTrees (who may or may not be Alucard)]] as the protagonist, fighting the [[FantasyAliens Demon Lord Galamoth]], who has brainwashed all of his minions in a bid to usurp him as Dark Lord.
280*** ''VideoGame/CastlevaniaJudgment'' features Dracula and other villains, but as they are also playable characters, other characters feature as antagonists in their own storylines. Then there's the True Story Mode, where all the characters are trying to take down the [[SNKBoss Time Reaper]], who is trying to [[EvilVersusEvil destroy Dracula]] and change history... [[spoiler:so that his master [[VideoGame/KidDracula Lord Galamoth]], whose involvement is only revealed through a [[SayMyName random voice line]], can take his place as ruler of the Netherworld.]]
281%%* In the licensed game ''VideoGame/TheCatInTheHat'', Mr. Quinn plays this role (as he did in the movie).
282* ''VideoGame/CaveStory'': Dr. Fuyuhiko Date, a MadScientist who orchestrates the takeover of the island and enslavement of the Mimingas through the Demon Crown.
283* ''VideoGame/{{Celeste}}'': For the first six chapters, [[EnemyWithin Part of You/Badeline]] is the physical incarnation of Madeline's insecurities that she came to the titular mountain to purge, and tries everything in her power to stop Madeline from reaching the summit and becoming at peace with herself. [[spoiler:However, at the end of Chapter 6, they learn to accept each other and become allies for the rest of the game.]] The last three chapters have NoAntagonist.
284* ''VideoGame/ChainedEchoes'': [[BigBadDuumvirate Frederik and Gwayn]], the former wants to use the Grand Grimoire as a weapon of war to force Valandis to unite against him, while the latter wants to power up the Grimoire to kill the Vaen.
285* ''VideoGame/ChildOfLight'' has Queen Umbra, master of the monsters that plague the land of Lemuria and [[spoiler:Aurora's WickedStepmother]].
286* ''VideoGame/ChromaSquad'': [[spoiler:Lord Gaga is the leader of the AlienInvasion, the villain directly responsible for all the conflicts from Season 3 onwards, and Tammy's ArchEnemy]].
287* ''VideoGame/ChronoTrigger'': Magus the Fiendlord, from the medieval era, is the creator of the [[EldritchAbomination planet-consuming parasite Lavos]], whose influence is felt in every time period and who is ultimately responsible for not one, but ''two'' [[TheEndOfTheWorldAsWeKnowIt extinction-level events]] (extinction of the Reptites and start of a long ice age in 65,000,000 B.C., and the destruction of the magical Kingdom of Zeal in 12,000 B.C.). The heroes are trying to prevent a third which will occur in 1999 A.D., and must kill Magus to prevent him from creating Lavos. [[spoiler:[[DiscOneFinalBoss Except he merely summoned and was trying to kill Lavos]], who is actually an alien from another world and is the real threat causing the extinction-level events.]]
288** ''VideoGame/ChronoCross'': Lynx is the demi-human soldier who aims to gain control of the Frozen Flame and El-Nido, putting him in conflict with [[TheHero Serge]] and his party, whom he wants to kill. [[spoiler:However, he is being mind-controlled by the supercomputer FATE, who [[NecessarilyEvil was built as a bulwark]] against the Dragon Gods and their race of the Dragonians, evolved Reptites, and their alternate universe, which seeks to invade this one. But all of them were manipulated by Belthasar, FATE’s creator, to stop the true threat: the Time Devourer, [[HijackedByGanon an evolved form of Lavos]] who wants to [[OmnicidalManiac destroy time and everything else]].]]
289* ''VideoGame/CIMATheEnemy'': Pike Nighttrap is one of the Crimson Nine (the most powerful CIMA) and the effective leader of their AlienInvasion. He and his fellow CIMA [[HopeCrusher feed off the hope]] of humans and seek to destroy the Gate Guardian heroes.
290* ''VideoGame/CityOfHeroes'' has a number of especially powerful and influential bad guys that compete to take over the world.
291** Lord Recluse, the EvilOverlord who [[PresidentEvil rules an island nation with an iron fist]], said nation being where ''City of Villains'' is set.
292** Nemesis, who [[GambitRoulette may or may not be behind darn near everything in the game]]. [[MemeticMutation It's all a Nemesis plot]].
293** Tyrant, the DimensionLord of the MirrorUniverse, EvilTwin of the game's biggest hero Statesman. (the BigGood?)
294** Rularuu the Ravager, somewhere between EldritchAbomination and [[GeniusLoci sentient dimension]] [[PlanetEater that eats other dimensions]] with a bad case of SplitPersonality.
295** The Center, the mysterious leader of the fascist paramilitary group known as The Council.
296* ''VideoGame/CliveBarkersJericho'': The Firstborn, the first being created by God that aims to destroy all of humankind as revenge against God for imprisoning it.
297* ''VideoGame/ClockTower'':
298** ''VideoGame/ClockTower1995'': [[EvilOrphanageLady Mary Barrows]], the owner of the titular mansion, having lured Jennifer and the other orphans to be killed by her murderous sons.
299** ''VideoGame/ClockTower2'': [[spoiler:Edward (actually Dan Barrows from the first game), who takes up the mantle of the Scissorman and attempts to murder Jennifer [[AvengingTheVillain as revenge for killing his mother]]]].
300** ''VideoGame/ClockTower3'': [[spoiler:[[GodhoodSeeker Lord Darcy Burrows]], a wicked 17th century British lord who possesses his descendant Dick Hamilton and intends on sacrificing Dick's granddaughter [[PlayerCharacter Alyssa]] in order to obtain godhood]].
301* ''VideoGame/ClockworkAquario'': Dr. Hangyo, a [[FishPeople Fish Man]] MadScientist who plans to use an army of [[MechaMooks wind-up aquatic creatures]] to TakeOverTheWorld.
302* ''VideoGame/CloesRequiem'': Cloé's curse is the thing keeping her trapped in the mansion, and Michel must destroy the curse to free her. [[spoiler:It is later revealed that [[MadArtist Alain Ardennes]], Cloé's [[AbusiveParents abusive father]], became the curse after she killed him in self defense.]]
303* ''VideoGame/CodeVein'': [[EvilutionaryBiologist Juzo Mido]], the leading Revenant researcher who's responsible for the creation of the Successors, as well as turning Cruz Silva into a destructive monster.
304* ''VideoGame/CodenameEagle'': [[EvilFormerFriend General Popov]], a power-hungry Russian general who murders the royal family and takes control of the Russian Empire with the intent of going to war with the rest of the world.
305* ''VideoGame/CommandAndConquer'':
306** ''VideoGame/CommandAndConquerTiberianSeries'' has the enigmatic [[DarkMessiah Kane]], leader of the Brotherhood of Nod. He's the driving force behind every game and, even when he's not the direct BigBad, is usually in some way responsible for or connected to the current villain, though things get [[MindScrew much more complicated and messy later on]].
307*** ''Firestorm'', the expansion to ''VideoGame/CommandAndConquerTiberianSun'', has [[spoiler:[[AIIsACrapshoot CABAL]], after it goes rogue from the Brotherhood and hijacks their cyborg army to take over the world for itself]].
308*** ''VideoGame/CommandAndConquer3TiberiumWars'' has the [[AlienInvasion Scrin]], who invade Earth after the fighting between the Global Defense Initiative and the Brotherhood of Nod draws their attention to the amount of Tiberium on Earth, replacing the (seemingly dead) Kain as the BigBad for once. However, [[spoiler:it later turns out that Kane (having faked his death, [[ContractualImmortality as always]]) intentionally led the Scrin to invade Earth so he could get his hands on their technology]].
309*** ''VideoGame/CommandAndConquerTiberianTwilight'' has a BigBadEnsemble between Gideon, leader of the [[RenegadeSplinterFaction Nod Separatists]], and [[spoiler:Colonel Louise James]]. Kane has a major role in the game, but it's as, bizarrely enough, the BigGood working with the GDI to contain the spread of Tiberium before it warps the whole planet. Instead, the conflict is drummed up by the former two each leading {{Renegade Splinter Faction}}s on either side trying to disrupt the alliance between Nod and the GDI and sabotage their attempts at stopping Tiberium.
310** ''VideoGame/CommandAndConquerRedAlertSeries''
311*** UsefulNotes/JosephStalin in ''VideoGame/CommandAndConquerRedAlert'', though the end of the Soviet campaign reveals [[spoiler:he was being used by [[HijackedByGanon Kane]] to further his own goals by causing disorder in Europe]].
312*** ''VideoGame/CommandAndConquerRedAlert2'' has Premier Alexander Romanov, who reignites the war between the Allies and the Soviets in the Allied campaign. [[spoiler:Though it later turns out he was being used by the psychic [[TheManBehindTheMan Yuri]], who fills the BigBad role more directly for the Soviet campaign and the expansion ''Yuri's Revenge''.]]
313*** ''VideoGame/CommandAndConquerRedAlert3'' has a BigBadEnsemble between the new Premier of the Soviet Union Anatoly Cherdenko, the [[UsefulNotes/ImperialJapan Empire of the Rising Sun]] and [[MegaCorp FutureTech]].
314* ''VideoGame/CommanderKeen'' has TheRival Mortimer [=McMire=] in Episode 3, who serves as the GreaterScopeVillain for the other episodes except in ''VideoGame/KeenDreams'', a GaidenGame where Boobus Tubber is the villain instead.
315* ''VideoGame/Conception2ChildrenOfTheSevenStars'' has [[spoiler:Enzea Marker, who manipulates all sides to forward his plan to open Pandora's Labyrinth and fill the Earth with Dusk Energy]].
316* ''VideoGame/ConkersBadFurDay'': [[CatsAreMean The Panther King]] rules the land and has his minions hunt down Conker to use him as a leg for his broken table. [[spoiler:[[DiscOneFinalBoss Until]] his assistant, [[WickedWeasel Ze Professor Von Kriplespac]], formerly the Weasel King, is revealed to have been manipulating him and [[TheStarscream hijacks his plans]].]]
317%%* ''[[VideoGame/{{TCT RPG}} The Colour Tuesday]]'': Officer Maxwell is the closest seen in the only released installment. The closest ''[[TheManBehindTheMan seen.]]''
318* ''VideoGame/{{Contra}}'': [[XenomorphXerox Gava]], the leader of Red Falcon, an evil organization of brainwashed humans and alien lifeforms seeking to dominate the world, is the most prominent big bad of the series. He acts as TheManBehindTheMan to Java in the first game before taking center stage in ''Super Contra'' and ''Contra III: The Alien Wars''.
319** First game: Java (not to be confused with Gava), the commander of the Red Falcon spearheading their invasion.
320** ''Operation C'' has Black Viper, Gava's sister who's leading the Red Falcon invasions this time around.
321** ''Contra: Hard Corps'': [[FallenHero Colonel Bahamut]], a RebelLeader looking to overthrow the Earth government.
322** ''Contra: Shattered Soldier'': [[spoiler:The BigBad at first is assumed to be Lance Bean, but the real villains in the game are the [[GovernmentConspiracy Triumvirate]]]]. In fact, it turns out that [[spoiler:the Triumvirate were [[GreaterScopeVillain truly responsible for the aliens attacking Earth in the previous games]], as they had secretly stole the [[ArtifactOfDoom Relic of Moirai]] prior to the start of the original Contra]].
323** ''Neo Contra'': [[NotSoWellIntentionedExtremist Master Contra]], the leader of the Neo Contra terrorist organization who plans to end all wars by destroying Earth.
324** ''Contra 4'': Black Viper returns to lead Red Falcon in another mass invasion.
325** ''VideoGame/HardCorpsUprising'': Emperor Tiberius, the head of the tyrannical Commonwealth dictatorship in control of the world that the player characters seek to dismantle.
326%%** ''Contra: Rogue Corps'' has General Phoenix, leader of the Phoenix Army.
327* ''VideoGame/{{Control}}'': [[EldritchAbomination The Hiss]], a malevolent mind virus wavelength that has infected [[EldritchLocation The Oldest House]] and is attempting to corrupt the [[ArtifactCollectionAgency Federal Bureau of Control]].
328* ''VideoGame/ConvictionSRPG'': The Dark Elf possessed Emperor Abyss and brainwashed him into thinking the only way to bring peace to the continent of Elwes is to conquer all other countries.
329* ''VideoGame/CorpseKiller'': Dr. Hellman, a [[MadScientist necro biologist]] who plans to create a [[OneWorldOrder new world order]] with his army of the undead.
330* ''VideoGame/CorpseParty'': In ''Blood Covered'' and ''Book Of Shadows'', Yoshikazu Yanagihori, once a beloved elementary school teacher, [[SanitySlippage went insane]] and [[EvilTeacher became known as the murderer]] of [[WouldHurtAChild three children]] in an incident from Heavenly Host elementary’s past. After his death, he haunted the school looking for more victims, and the children’s killer is now the master of the AlternateDimension school keeping everyone trapped inside. [[spoiler:The ''real'' killer, that is: [[DiscOneFinalBoss Yoshikazu was framed for the crime]] by Sachiko the Girl in Red, who is the [[EnemyWithout incarnation of Sachiko Shinozaki’s hatred after being killed horribly]].]]
331** In the original [[VideoGame/CorpsePartyPC98 PC-98 game]], [[spoiler:Sachiko is also the antagonist, although her backstory differs somewhat]].
332** Yoshikazu [[spoiler:or rather, Sachiko]] takes a back seat in ''2U'', leaving [[spoiler:[[DragonAscendant Yuuya Kizami]]]] to take the position. [[spoiler:He antagonizes the other students throughout in many ways, including attempting to sabotage the cooking competition and stealing the [[TomeOfEldritchLore Book of Eibon]] to hijack Heavenly Host]].
333** The spin-off manga ''Another Child'' has Saki Akagiri, the ghost girl messing with Heavenly Host and murdering Tamaki’s friends (who are [[AssholeVictim mean bullies]]) as part of her [[BullyHunter supernatural crusade against bullies]].
334** ''[[GrandFinale Blood Drive]]'' introduces Misuto Kiriya as this, as he aims to control Heavenly Host for himself [[spoiler:and take revenge on humanity]], [[BigBadEnsemble as well as Sachi]], Sachiko’s [[CainAndAbel unborn and jealous sister]] who is the new master of HH; it’s later revealed that [[spoiler:[[DiscOneFinalBoss they’re both a secondary threat]] to [[GeniusLoci Heavenly Host]]/[[HijackedByGanon Nirvana herself]], and that “Red Sachiko” [[DemonicPossesion is basically an avatar for its will]], the Witch Queen, who serves as the FinalBoss]].
335* ''VideoGame/CorruptionOfLaetitia'': [[SinisterMinister Cardinal Alfredus Marian]] starts the game by betraying the heroine and stealing her powers as part of his plans to bring order to the two countries he has influence over. He's also responsible for starting an industrial revolution for the sake of bolstering his military power, but ignores the environmental damage he causes to both his own people and various monster races, making his downfall the main goal of the game.
336* ''VideoGame/CosmicStarHeroine'''s chief villain is Dominic, director of API who aims to use the MindControlDevice the protagonists found in the lab on Rhomu to eradicate free will of everyone. [[spoiler:Later he is superseded by Eternity, an EldritchStarship that is less subtle in its methods, its first action being to head straight to Rhomu to rain destruction on the Scimerex hive.]]
337* ''VideoGame/CrashBandicoot'': Uka Uka. While Dr. Neo Cortex seemingly was behind all the events in the [[VideoGame/CrashBandicoot1996 first]] [[VideoGame/CrashBandicoot2CortexStrikesBack two]] Crash games, it was eventually revealed in the [[VideoGame/CrashBandicoot3Warped third game]] that he did everything under Uka Uka's orders. However, in ''VideoGame/CrashMindOverMutant'', Cortex double-crosses Uka Uka and becomes the villain himself. There are also a few standalone villains:
338** ''VideoGame/CrashTeamRacing'': [[AliensAreBastards Nitrus Oxide]], who comes to Earth to challenge the world's fastest racers under the threat of turning the planet into a parking lot and enslaving the population.
339** ''VideoGame/CrashNitroKart'': Emperor Velo XXVII, who kidnaps the best racers on Earth (namely Crash, Cortex, and the rest of the cast) to prove his own skill in racing.
340** ''VideoGame/CrashTwinsanity'': The Evil Twins, who've come from the Tenth Dimension to destroy Crash's world as revenge for Cortex experimenting on them. The game's sub-plot has N. Tropy (who is under Uka Uka) leading the villains' hunt for treasure.
341** ''VideoGame/CrashTagTeamRacing'': [[spoiler:Willie Wumpa Cheeks]], being the one who stole Von Clutch's Power Gems.
342** ''VideoGame/CrashOfTheTitans'': [[spoiler:Nina Cortex, who takes over construction of the Doominator to destroy Wumpa Island. ([[BigBadWannabe At least the console version]]).]]
343** ''VideoGame/CrashBandicoot4ItsAboutTime'': Dr. N. Tropy hijacks Cortex's plans and teams-up with [[spoiler:his alternate dimension female counterpart]] to destroy the multiverse and remake it InTheirOwnImage. [[spoiler:Although Cortex ends up retaking the position after they're taken care of and serves as the FinalBoss.]]
344* ''VideoGame/CrayonChronicles'': Stratolustrious Von Denderbreak the 37th, who's kidnapped your friends.
345* ''VideoGame/CreepyCastle'': Darking, who want to establish peace by [[spoiler:removing people's emotions. Then Possessor awakens and the characters have [[TheEndOfTheWorldAsWeKnowIt much bigger problems now]]]].
346* ''VideoGame/CrescentPrism'': Count Chroma is an EvilOverlord who seeks to use his army of robots and the Prism Stones to conquer the world, and Merryday happens to contain the last of the stones he needs.
347* ''VideoGame/CriminalCase'':
348** ''VideoGame/CriminalCaseGrimsborough'' has [[spoiler:Milton Grimmes]], leader of the AncientConspiracy known as the Crimson Order that has been controlling Grimsborough from the shadows for centuries.
349** ''VideoGame/CriminalCasePacificBay'' has [[spoiler:Albert Tesla]], a MadScientist and supposed creator of Pacific Bay who has been planning to destroy the city and eventually the world to enact his master plan of [[spoiler:forcing everyone to live inside [[TheMetaverse his virtual utopia]] with him as the supreme ruler]].
350** ''VideoGame/CriminalCaseWorldEdition'' has El Rey AKA [[spoiler:Hector Montoya]], the leader of [[NebulousEvilOrganisation SOMBRA]] and [[spoiler:[[PassingTheTorch successor]] of [[GreaterScopeVillain Arsenio Castillo]], the original founder of the organization]].
351** ''VideoGame/CriminalCaseMysteriesOfThePast'' has a [[TheBigBadShuffle Big Bad Shuffle]] between the corrupt [[TheBadGuysAreCops Concordian Police Department]] (led by [[spoiler:Eleanor Halsted and later Thaddeus Mulroney]]), the [[TheIrishMob Irish gang]] (led by Finley Flanagan [[spoiler:and later Seamus O'Neill]]), the [[TheMafia Italian gang]] (led by Vittorio Capecchi [[spoiler:and later Franca Capecchi]]), and the morally rotten [[BigScrewedUpFamily Rochester family]] (led by Horatio and Malcolm Rochester) as the main antagonists at some point in the season, with all of them causing equal amount of trouble for the player and their team. [[spoiler:In the end, all of them are defeated either by the arrest or death of their leaders, making path for the FinalBoss to step in: [[MayorPain Mayor Justin Lawson]], who undergoes a BigBadSlippage and becomes a dictator after witnessing the wave of crime and corruption brought by so many criminals, turning him into the main antagonist of the game's last stretch]].
352** ''VideoGame/CriminalCaseTheConspiracy'' has Rozetta Pierre, the CorruptCorporateExecutive of [[EvilInc DreamLife]] [[spoiler:and leader of [[TheConspiracy Ad Astra]]]] whose actions are constantly causing trouble for the police department throughout the game. [[spoiler:And then she's revealed to be just a pawn for [[EvilMatriarch her mother]], [[GreaterScopeVillain Denise Daniels]]]].
353** ''VideoGame/CriminalCaseTravelInTime'' has [[spoiler:Nebet/Nefertiti]], the princess of the Ptolemy Dynasty responsible for stranding the team in the past and altering the timeline into a BadFuture.
354** ''VideoGame/CriminalCaseSupernaturalInvestigations'' has the [[spoiler:Demon Queen]], whose servants are constantly causing trouble for the team and other supernatural creatures in an effort to [[spoiler:release her from her prison to destroy the world]].
355** ''VideoGame/CriminalCaseCityOfRomance'' has [[spoiler:Eleonora Macaron]], the [[spoiler:daughter of [[TheDon mob boss Antoine Macaron]]]] who is trying to TakeOverTheCity.
356%%* ''VideoGame/CriminalGirls'' has [[spoiler:Ayano Himekami for the main storyline. The post-game of the remake has the Reformation Program itself acting as the main opposition]].
357%%** ''VideoGame/CriminalGirls2PartyFavors'' has [[spoiler:Maya]].
358* ''VideoGame/{{Crowscare}}'': [[spoiler:Venna the witch turns out to be plotting to kill the villagers and is manipulating the protagonist Ryo into sabotaging the Harvest Festival so she and her “friends” can eat them]].
359* ''VideoGame/CryOfFear'': [[spoiler:Book Simon, the character you play as for the majority of the game, as well as the protagonist of Simon’s book. He is the manifestation of Simon’s mental issues and in almost every ending, he leads to Simon committing a Murder-Suicide. Defeating Book Simon leads to the Good ending, though it's more bittersweet as Simon's fight with him leads to a psychotic break where he kills two cops in real life]].
360* ''VideoGame/CultOfTheLamb'': The Bishops of the Old Faith, who rule over the land and are responsible for the genocide of the Lamb's species. [[BigBadEnsemble Alongside them]], is He Who Waits, an ancient deity trapped by the Bishops using the Lamb to free him.
361* ''VideoGame/{{Cuphead}}'': [[{{Satan}} The Devil]], who forces Cuphead and Mugman to collect the souls of his debtors. In return, they get to keep their souls (that Cuphead foolishly bet). In the end, the two decide to fight the Devil and free all of the bosses they fought from his contracts.
362** ''The [[FunWithAcronyms Delicious Last Course]]'': [[spoiler:Chef Saltbaker is revealed to be a power-hungry madman who wants the Wondertart only for himself. He captures one of the three cups to use their soul as the final ingredient of the Wondertart, and the remaining two are forced to battle him in "A Dish to Die For" to save their friend]].
363* ''VideoGame/{{Cyberbots}}'' has the Earth Force Federation and its creation, G.O.D., a giant brain-like lifeform that has decided to wipe out humanity after considering it is its own greatest enemy.
364* ''VideoGame/{{Cyberpunk 2077}}'': Actually averted. While there are plenty of factions who are powerful and antagonistic to V, the ones that are actively malicious are generally small-fry with little to no bearing on the main plot, and the ones that have the kind of power we usually associate with this trope are generally willing to "live and let live" or completely oblivious to V's existence until desperation, greed or some other factor compels V to kick the hornet's nest. The closest thing to a true Big Bad is a combination of bad luck and poor lifestyle choices on V's part.
365[[/folder]]
366
367[[folder:D]]
368* ''VideoGame/DaemonSummoner'': [[AlwaysIdenticalTwins The Vampire Twins]]. They aim to summon the titular daemon to destroy the world and it's their killing of James Farrington-Higgs' family that drives him to become a vampire hunter.
369* ''VideoGame/{{Daikatana}}'': [[CorruptCorporateExecutive Kage Mishima]], who used the Daikatana to travel back in time and make himself the tyrannical dictator of the world, leaving Hiro to try and take the sword and use it to SetRightWhatOnceWentWrong.
370* ''VideoGame/{{Damnation}}'': [[CorruptCorporateExecutive Lord Prescott]], the head of [[MegaCorp Prescott Standard Industries]], who after spending 20 years supplying weapons to both sides of the Civil War, decides to use his vast army to conquer the world.
371* ''VideoGame/DantesInferno'': [[{{Satan}} Lucifer]] himself, who kills Beatrice and sends Dante on a quest to save her soul.
372* ''VideoGame/DarkCloud'': The Dark Genie, who threatens to spread his evil across time and destroy the world.
373** ''VideoGame/DarkChronicle'': Emperor Griffon/[[spoiler:the Dark Element]], who aims to destroy all of humanity; past, present, and future.
374* ''VideoGame/TheDarkPicturesAnthology'':
375** ''VideoGame/ManOfMedan'': The pirates and the ghosts onboard the ship constantly threaten and depending on your choices will come close to killing or outright kill the main characters. [[spoiler:However, it's revealed that the ghosts are non-existent, leaving the pirate leader Olsen as the story's biggest threat.]]
376** ''VideoGame/LittleHope'': [[spoiler:[[SinisterMinister Reverend Simon Carver]], who uses Mary Milton to accuse people of witchcraft and have them killed]].
377** ''VideoGame/HouseOfAshes'': The Ancient One, the leader of the vampires that threaten the main characters.
378** ''VideoGame/TheDevilInMe'': Granthem Du’Met, a SerialKiller inspired by H.H. Holmes who lures the documentary crew into the "Murder Castle" replica and attempts to murder them all.
379* ''VideoGame/DarkSouls'' series:
380** ''VideoGame/DemonsSouls'': [[EldritchAbomination The Old One]] is the source of the Colorless Fog, the spread of the demons, the fall of Boletaria, and the slow death of the world. It's also the source of the setting's magic (called soul arts), and is heavily implied to be [[spoiler:"{{God|IsEvil}}"]].
381** ''VideoGame/DarkSoulsI'': Gwyn, Lord of Sunlight, is the leader of the Lords and the FinalBoss. The coming end of the Age of Fire is caused by simple entropy, but [[WellIntentionedExtremist the attempts of him and his subordinates to prolong it by keeping the First Flame alive]] are the cause of much of the bad happenings in the game. [[FallenHero Originally a great hero]], he caused the Undead Curse and Hollowing by [[spoiler:placing the Darksign on the Pygmies and their descendants]], and is [[spoiler:holding back the Dark even though it is [[DarkIsNotEvil not evil]] but part of a natural cycle]]. Even things such as the birth of Demons, the fall of many kingdoms after Lordran, and even the end of the world itself all have some ties to Gwyn in some way.
382*** ''Artorias of the Abyss'' DLC: Manus, Father of the Abyss who is implied to be the Furtive Pygmy, is the one who defeated and corrupted [[FallenHero Artorias]], kidnapped Princess Dusk of Oolacile, and is spreading the darkness of the Abyss over the land of Oolacile.
383** ''VideoGame/DarkSoulsII'': King Vendrick, the founder of Drangleic, is the one who brought his kingdom to ruin in the pursuit of power, and is the FinalBoss. [[spoiler:Except he is a DiscOneFinalBoss. The true villain and final boss is his wife [[GodSaveUsFromTheQueen Queen Nashandra]], who is a Soul Fragment of the aforementioned Manus, and seduced Vendrick into warring against the giants, while also being the one who spread the undead plague so she can get the First Flame for herself. Aldia the Scholar Of The First Sin, the brother of Vendrick and co-founder, is the TrueFinalBoss after the game got updated.]]
384** ''Videogame/DarkSoulsIII'': [[spoiler:Pontiff Sulyvahn]] and the {{four|IsDeath}} Lords of Cinder are the primary antagonists, [[spoiler:while the [[FinalBoss Soul of Cinder]] is a fusion of them and every other Lord, serving as an embodiment of the First Flame, and [[FinalBoss Slave Knight Gael]] of ''The Ringed City'' DLC becomes an embodiment of the Dark Soul]]. The conflict is caused by a combination of simple entropy and the Lords who were supposed to keep it line abandoning their duties, [[BigBadEnsemble all for different reasons and without communication with each other]]:
385*** The Abyss Watchers, members of the premier unit of Farron's Undead legion are the collective first Lord, and seek to protect humanity by eradicating the spawn of the Abyss, but are [[KnightTemplar overzealous]] in achieving this goal.
386*** Aldritch, Saint of the Deep/Devourer of Gods, and [[spoiler:Pontiff Sulyvahn]] are the [[BigBadDuumvirate two leaders]] of the Cathedral of the Deep and the antagonists of the first half of the game, much of which is spent dismantling forces they either directly command or created. [[spoiler:Sulyvahn]] has alliances with numerous other evil sects including Rosaria's Fingers and the surviving nobility of the Profaned Capital, multiple lore-vital characters and settlements were victimized by him, and he was implied to be TheCorrupter who caused Lothric to lose his faith in the Fire to begin with. While [[spoiler:Sulyvahn]] is outranked by Aldrich, ''he's'' the one who fed [[spoiler:Gwyndolin]] to Aldrich (thus allowing Aldrich to ascend to godhood), the one actually ruling Irithyll and the Cathedral while Aldrich feeds in a basement, and the one taking action. The only thing keeping them from being the wholesale villains is that they are killed 2/3 of the way through the game, though their legacy is felt until the end.
387*** Yhorm, the Giant, is the descendant of an ancient conqueror, and by far [[TokenGoodTeammate the nicest of the Lords]]. He is either the second or third Lord fought, depending on the decisions of the player.
388*** Princes Lorian and Lothric are the final Lord faced. They were supposed to rekindle the flame but chose not to, which causes the coming end of the world, and they interfere with the Ashen One's quest, serving as the penultimate boss. However, they do not do anything actively villainous, instead just holding up in their tower. They just want to be left alone.
389*** The final boss isn't a real BigBad, but it is still important in the overarching plot: [[spoiler:The Soul of Cinder/Incarnation of Kings, embodiment of the First Flame and a composite of all who chose to link it, including [[WellIntentionedExtremist Gwyn]], manifested to defend the First Flame]].
390*** ''Ashes of Ariandel'' DLC: [[TheCorrupter Sister Friede]], although separate from the rest of the game's lore and plot, is the [[DragonInChief de-facto leader]] of the Sable Church and the cause of the painted world of Ariandel being overrun by the rot. She convinced Father Ariandel not to let the flame burn the Painted World away so a new one may be born, deployed her Corvian Knights to stop both the Ashen One and the forlorn Corvians from ruining her plot, and kidnapped the [[MysteriousWaif Painter]] to make sure she won't attempt to create another world.
391*** ''The Ringed City'' DLC: It doesn't have a real BigBad, but the final boss is important in terms of the overall story: [[spoiler:[[WellIntentionedExtremist Slave Knight Gael]], the embodiment of the Dark Soul, created when Gael ate the Pygmy Lords to make the Dark Soul in himself so the Painter can use his blood, infused with the Dark Soul, to paint a new world]].
392* ''VideoGame/TheDarkness'': [[TheDon Paulie Franchetti]], who Jackie Estacado targets as revenge for leaving him for dead.
393* ''VideoGame/{{Darksiders}}'':
394** ''VideoGame/DarksidersI'' has the Destroyer, [[spoiler:who is revealed to be Abaddon, the former leader of the Hellguard, where he rallies his forces of Demons from Hell on the ruined Earth]].
395** ''VideoGame/DarksidersII'' has the Avatar of Chaos, [[spoiler: aka Absalom]], who is the physical incarnation of the Corruption, being responsible for plaguing the realms and is the real, final threat to Death.
396** ''VideoGame/DarksidersIII'' has the Seven Deadly Sins being a [[BigBadEnsemble collective Big Bad]], [[spoiler:but Envy seeks to become the sole one and proves herself to be the main threat]].
397* ''VideoGame/{{Darkstone}}'': Draak, an evil dragon who intends on using the Darkstone to drain the lives of everyone in the kingdom and become a god.
398* ''VideoGame/{{Darkwatch}}'': [[VampireMonarch Lazarus Malkoth]], the founder of Darkwatch turned monstrous vampire who Jericho accidentally released and is now terrorizing TheWildWest with his army of the damned. [[spoiler:After he's dealt with, [[DarkActionGirl Tala]] takes over the position, with Jericho joining her depending on the player's choice.]]
399* ''VideoGame/DawnOfTheMonsters'': [[spoiler:Conrad Fosco, the former CEO of Syncor and current commander-in-chief of DAWN]], is revealed to be the one behind the Nephilim attacks on humanity and [[spoiler:has been using his old company to mass-produce ATOM units that he ultimately siccs on the Sunrise squad -- seeking to make a profit by RunningBothSides. He also had Professor Goro Maki assassinated when he learned too much about what Syncor was up to]].
400%%* ''VideoGame/DawnOfWar'':
401%%** ''Dawn of War'' has [[GeneralFailure Lord Bale]] [[spoiler:before being usurped by [[EvilSorceror Sorceror Sindri Myr]]]].
402%%*** ''Winter Assault'' has a BigBadEnsemble between [[GreenAndMean Warboss Gorgutz]] and Lord Crull.
403%%*** ''Dark Crusade'' has either [[EvilOverlord Lord Eliphas the Inheritor]], [[TheSoulless Necron Lord of Kronus]], and [[JokerImmunity Warboss Gorgutz]].
404%%** ''Dawn of War II'' is a BigBadEnsemble of [[HiveMind the Tyranid Hive Tyrant Alpha]], the Eldar, and the Orks.
405%%*** ''Chaos Rising'' has [[FatBastard Ulkair]].
406%%*** ''Retribution'' has [[spoiler:Chapter Master Azariah Kyras]].
407%%** ''Dawn of War III'' has [[spoiler:[[EldritchAbomination the Storm Prince]]]].
408* ''VideoGame/DaysGone'' has ''two'' villains of both the first and second half of the game's story:
409** [[spoiler:Carlos/Jessie Williamson is the villain of the story's first half. He is the enigmatic but violent leader of the Rippers and an ex-member of Mongrels. He is revealed to be the nemesis of Deacon and Boozer, after his Mongrel tattoo was burnt off via a blowtorch. However, in terms of the villainy scale, he is only a DiscOneFinalBoss.]]
410** [[spoiler:Colonel Garret is the villain of the story's second half, and unlike Carlos, he is later revealed to be the story's true Big Bad, after he begins JumpingOffTheSlipperySlope, following the death of Arturo Jiminez, the Militia's only doctor. Because of this, he begins his extermination campaign of targeting rival human camps with his militia army.]]
411* ''VideoGame/{{Deadbolt}}'': Ibzan, [[spoiler:leader of the Dredged and possibly a former Reaper]].
412* ''VideoGame/TheDeadCase'': [[spoiler:Greg Toberen, a SerialKiller who's directly responsible for the PlayerCharacter's murder and attempts to make his fiancé his next victim]].
413* ''VideoGame/DeadlyPremonition'':[[spoiler:Forrest Kaysen]], who caused most, if not all of, the problems in the story ([[spoiler:the murders that take place in Greenvale, and driving the townspeople insane with purple gas]]). It's even to the point he's responsible for [[spoiler:horribly mentally scarring the original personality of the one called York, the original personality being Zach]].
414** ''VideoGame/DeadlyPremonition2'': Lena Dauman/Professor R. Uniquely, who orchestrated the whole crime plot. While she dies a little over the halfway into the game, York still has her minions and Kaysen to deal with.
415%%* ''VideoGame/DeadOrAlive'' series:
416%%** Raidou in the first.
417%%** Tengu in the second.
418%%** Omega / [[spoiler:Genra]] in the third.
419%%** ALPHA-152 in the fourth and fifth.
420%%** MIST, led by Victor Donovan, is this in the sixth game, though the only members seen are Christie (who's been present in the series since the second game) and newcomer [=NiCO=], the latter the one behind the revival project [[spoiler:which succeeds in bringing back game 1's Big Bad Raidou, as [=NiCO=] is trying to bring back her dead father]].
421%%* ''VideoGame/DeadIsland'' has The Voice [[spoiler:who seems to be Ryder White, but it's really Charon/Kevin]].
422%%** ''VideoGame/DeadIslandRiptide'' has [[spoiler:Frank Sherpo]].
423* ''Franchise/DeadRising'':
424** ''VideoGame/DeadRising'' has Carlito Keyes, who orchestrated the Willamette outbreak and plans to have it spread worldwide. However, [[GeneralRipper Brock Mason]] takes over as the main villain of the Overtime mode, being behind the FieryCoverup of the Willamette outbreak, as well as [[spoiler:the Santa Cabeza massacre and cover-up that drove Carlito to villainy]].
425** ''VideoGame/DeadRising2'' has [[TheHeavy TK]] throughout the entire game, having framed Chuck for the outbreak and using it as an opportunity to loot the city. Although the true mastermind behind the outbreak is revealed to be [[spoiler:Sullivan]], or [[spoiler:Stacey in the alternate timeline of ''Off the Record'']].
426** The ''Case West'' DLC seems to reveal the series' GreaterScopeVillain in the form of the Director of Phenotrans, Marian Mallon.
427** ''VideoGame/DeadRising3'' has a BigBadDuumvirate between Marian Mallon, who takes advantage of the outbreak to keep Phenotrans in business, and General John Hemlock, [[DragonWithAnAgenda who has his own plans]] to create his own controlled outbreaks so he may continue to rule over the populous as a dictator. That said, towards the end of the game, Hemlock kills Marian, leaving him as the sole villain.
428** ''VideoGame/DeadRising4'' has Calder. Obscuris's operations within the city are to capture and contain him and the data he carries, which is also the driving motive behind Frank tracking him. He is also the cause of the outbreak, as he's been wandering in the sewers of Willamette all this time carrying the old strain of the parasite.
429* ''Franchise/DeadSpace'':
430** ''VideoGame/DeadSpace1'' has two, Mercer and [[spoiler:[[TheMole Kendra]]]]. The situation is unique as you fight neither of them, though you do fight what may or may not be considered as the third Big Bad, the HiveMind. Considering it's puppeteering the other Necromorphs and is the FinalBoss... Mercer even talks about "... the Hive Mind's gift", suggesting he considers himself to be its servant.
431** ''VideoGame/DeadSpace2'' has Hans Tiedmann at first, with him spending the game trying to keep Clarke and Ellie from getting to the the maker, [[spoiler:until Nicole/The Golden Marker (12B) reveals herself as the true Big Bad]].
432** ''VideoGame/DeadSpace3'' has Jacob Danik, the leader of The Circle. After bringing ruin to [=EarthGov=] and its colonies, he hunts down Isaac as he's the only one capable of stopping his plan of bringing [[AssimilationPlot Convergence]] to the galaxy.
433* ''VideoGame/DeadToRights'': [[spoiler:Mayor Pinnacle, Prince Fahook, and Police Chief Hennessey]] are the head figures in the conspiracy behind the death of Jack's father and the demise of pretty much every single one of Jack's allies over the course of the game. All three are in cahoots, but have their own separate agendas.
434* ''VideoGame/{{Deathloop}}'': The Visionaries, a group of eight individuals who founded the AEON Program by creating the time loop in Blackreef to live forever and who Colt must kill in order to end the loop.
435* ''VideoGame/DeathStranding'' has the terrorist Higgs, who seems to be a menacing villain, and serves as [[TheHeavy the main threat]] to [[PlayerCharacter Sam]] throughout the game, but is [[BigBadWannabe ultimately just a pawn]] and the [[TheDragon enforcer]] for the real villain, and [[spoiler:[[DiscOneFinalBoss is defeated before the game's end]]]]. The real villain is actually [[spoiler: [[ApocalypseMaiden Amelie]], the [[EldritchAbomination Extinction Entity]] who brought about the Sixth Death Stranding and is destined to bring about the Last Stranding, the extinction of all life on Earth. She wants to end suffering by forcefully hastening the Last Stranding]]. [[BigBadEnsemble There is also]] the threat of Cliff, a HumanoidAbomination who attacks Sam [[ItMakesSenseInContext during "supercell" storms that drag Sam to areas based on historical wars]], but Cliff is more of an ArcVillain who has little true relevance to the main plot, figuring more into the backstory and the background of certain characters.
436* ''Creator/DeepSeaPrisoner'' verse:
437** ''VideoGame/MogekoCastle'': There are three antagonists Yonaka Kurai faces in her quest to escape the titular castle:
438*** [[TheCaligula King mogeko]] created the titular castle and the [[CuteAndPsycho Mogeko species]] and is trapping Yonaka inside so they can rape her.
439*** [[DragonInChief Moge-ko]] is a sadistic Mogeko girl who is the king's enforcer but terrifies even him and wants Yonaka to herself.
440*** [[spoiler:Shinya Kurai, Yonaka's brother, killed their parents and wants to kill Yonaka herself, but is [[PlotIrrelevantVillain otherwise unrelated to the main plot]].]]
441** ''VideoGame/TheGrayGarden'': [[SatanicArchetype Ivlis]] is the Devil of the Flame World and leader of the terroristic Flame Devils who starts the attack on the Gray Garden and sends his minions to cause chaos and destruction, with the ultimate goal of killing and usurping [[BigGood Etihw and Kclab]], then using their powers to conquer the other worlds as well. [[spoiler:Though the ending reveals his true motives were to take revenge on the [[JerkassGods other gods and devils]] and [[WellIntentionedExtremist free his people from their tyranny]], and an [[HiddenVillain unknown traitor]] within the Garden was [[GreaterScopeVillain giving him directions]].]]
442** ''VideoGame/{{Wadanohara}}'': [[TheEvilPrincess Princess Tosatsu]] is leading Tosatsu Kingdom in a war against the Sea Kindgom to take the throne from Princess Uomi, as she tried long before. [[spoiler:[[DiscOneFinalBoss Except]] she's not the mastermind; [[DeviousDolphins Sal/Syake-san]], the [[TheMole traitor]], is the one who manipulated her into attacking as part of his plan to unseal his master. In the third act, Princess Mikotsu, Uomi's real sister and Sal's boss, takes this position upon becoming unsealed.]]
443* ''VideoGame/DefaultDan'', as part of its inversion of [[Franchise/SuperMarioBros Mario]] tropes, has the Princess kidnap Dan’s [[DistressedDude turtle-dragon friend]], sparking Dan’s quest to save him.
444* ''VideoGame/{{Deltarune}}'':
445** The Knight is the one responsible for creating the excess Fountains of Darkness, which in turn throw off the balance between Light and Dark, forcing the heroes to seal them off while fighting against the {{Arc Villain}}s who stand against them. [[spoiler:If too many Fountains are opened, [[GreaterScopeVillain the Titans]] will awaken and cause TheEndOfTheWorldAsWeKnowIt, turning any remaining Darkners [[TakenForGranite into stone]] and forcing the Lightners to live in an endless night.]]
446** In Chapter 2's secret route, [[spoiler:the SOUL (read: {{you|Bastard}}) and Spamton pull a BigBadDuumvirate-turned-BigBadEnsemble. In this route, the SOUL forces Kris to [[CorruptTheCutie manipulate and abuse Noelle into becoming a murderer]], while Spamton directly assists them by telling them how many people they have to kill, before selling the [=ThornRing=] that Noelle will use to kill Berdly. Spamton would then use this opportunity to take over Queen's Mansion for himself, before fighting Kris as [[OneWingedAngel Spamton NEO]] to prevent them from sealing the Dark Fountain]].
447* ''VideoGame/DemonGaze'' has [[spoiler:Lu Lunark/Lulu/Luna, [[EvilAllAlong who is actually a demon]] seeking to revive the GreaterScopeVillain, Sol]].
448** ''VideoGame/DemonGaze2'' has Lord Magnastar, an EvilOverlord who kills people and converts them into Star Power with the Astral Furnace.
449* ''Demonophobia'': Lucifer/the Butcher is the keeper of Hell who chases after Sakuri Kunikai and is keeping her from escaping. [[spoiler:[[DiscOneFinalBoss Until]] the end reveals that Ritz, Sakuri's guide, [[TreacherousAdvisor was the demon who trapped her in the first place]], and stole her memory so she could [[SealedEvilInACan break him out]].]]
450%%* ''{{VideoGame/Def Jam|Series}}: Fight for NY'': [[SmugSnake Crow]].
451* ''VideoGame/DeptHeaven'' series:
452** ''VideoGame/RivieraThePromisedLand'': [[spoiler:Hector of the Seven Magi]] is the mastermind of the demonic invasion of Riviera as part of a plan to conquer Asgard and [[GodhoodSeeker become a god]]. His influence also extends to the other games in the series, making him the main villain as well.
453** ''VideoGame/YggdraUnion'': [[TheEmperor Emperor Gulcasa]] is the leader of the [[TheEmpire Bronquia Imperial Army]] who intends to TakeOverTheWorld [[spoiler:to [[WellIntentionedExtremist bring peace to it]]. [[DiscOneFinalBoss However]], his strategist, [[FallenAngel Nessiah Aries Artwaltz]], has been [[TheManInFrontOfTheMan manipulating him]] as part of his own revenge plot against the gods for casting him down to Asgard]].
454** ''VideoGame/KnightsInTheNightmare'': [[SatanicArchetype Lord Zolgonark]] is the Demon Lord of the Underworld who allies himself with [[SinisterMinister Cardinal Capehornus Mirza Lucius]] and [[WickedWitch General Yelma Ul Varomone]] to invade and conquer the kingdom of Aventheim.
455* ''VideoGame/Depict1'': [[MissionControl The benefactor/shadow]] actively works against the protagonist, lying to them about how to escape, to keep them trapped. The true end reveals them to be [[spoiler:the protagonist's LivingShadow who wants to 'protect' them by ensuring they never leave]].
456* ''Franchise/DeusExUniverse'':
457** ''VideoGame/DeusEx'' has Bob Page, the leader of Majestic-12 and the mastermind behind the events of the game.
458** ''[[VideoGame/DeusExInvisibleWar Invisible War]]'' has Saman, the head of The Templars.
459** ''[[VideoGame/DeusExHumanRevolution Human Revolution]]'' doesn't really have a main antagonist, but Hugh Darrow comes the closest. Bob Page from the original game serves as the GreaterScopeVillain though he is never encountered directly, and Pieter Burke is is the antagonist of ''The Missing Link'' DLC.
460** ''[[VideoGame/DeusExMankindDivided Mankind Divided]]'' has Lucius [=DeBeers=], the leader of the Illuminati. However, his actual involvement is minimal, with [[spoiler:Viktor Marchenko]] serving as TheHeavy.
461* The ''VideoGame/DevilMayCry'' series has one in each game:
462** ''VideoGame/DevilMayCry1'' has Mundus, the Demon King, who lures Dante to Mallet Island with the help of his creation Trish so he finish off the last remaining blood of Sparda after he spilled the blood of the wife and kidnapped and enslaved the older twin, Vergil.
463** ''VideoGame/DevilMayCry2'' has Arius, the CEO of Uroboros, who wishes to use the power of the Arcanas to resurrect the Demon King Argosax so that he will be blessed with absolute immortality to rule over the entire world.
464** ''VideoGame/DevilMayCry3DantesAwakening'' has [[spoiler:Arkham]], who manipulates both Dante and Vergil along with his own daughter so that he can unlock the gate to the Demon World and obtain the ultimate power of Sparda.
465** ''VideoGame/DevilMayCry4'' has [[spoiler:Sanctus]], the leader of the Order of the Sword, who wishes to use Sparda's power as the Savior in order to cleans the world of its evils and rule over it.
466** ''VideoGame/DevilMayCry5'' has Urizen, the Demon King, who planted the seed of the Qlipoth tree in Red Grave City, draining the lives of the citizens there in order to bear a fruit that will grant him absolute power. [[spoiler:However, he is later defeated and assimilated into his true identity: [[WildCard Vergil]], who previously inadvertently created Urizen as part of his desire to gain power to defeat his brother.]]
467** ''VideoGame/DMCDevilMayCry'' has Mundus, the demonic EvilOverlord secretly ruling the world.
468* ''VideoGame/DevilsThird'': Isaac Kumano, the head of the terrorist organization the School of Democracy, who intends to bring about peace by rebelling against the world and killing everyone who they consider an enemy to that peace.
469* ''VideoGame/{{Devotion}}'': The [[StringyHairedGhostGirl ghost lady]] is the main enemy stalking Du Feng Yu in his quest to find Mei Shin. [[spoiler:[[DiscOneFinalBoss Or so it seems]], but the ghost is in his head. In truth, Mentor Heuh is the one responsible for the disappearance of Mei Shin, as she is the leader of the [[ScamReligion Cigu Guanyin cult]] who manipulated [[VillainProtagonist Feng Yu]] into worship and got Mei Shin killed through a ritual.]]
470* ''VideoGame/{{Diablo}}'', the Lord of Terror, is the BigBad of the series that bears his name, though in ''VideoGame/DiabloII'', he shares this status with his two brothers, Mephisto and Baal, as the "Prime Evils." In ''VideoGame/DiabloIII'', it's Diablo again [[spoiler:using Leah as his vessel]], and in the ''Reaper of Souls'' expansion, it's [[spoiler:the fallen angel Malthael]].
471* ''VideoGame/DiceAndTheTowerOfTheReanimatorGloriousPrincess'': The Reanimator is the main antagonist of the game, since she's in charge of all the Dark Ones in the tower and has the elixir that Bambooblade needs to cure Princess Gloria.
472* ''Franchise/{{Digimon}}'':
473** ''Digimon World'' series:
474*** ''VideoGame/DigimonWorld'' has [[spoiler:Analogman, a human who wishes to enslave all Digimon and take over the Digital World; with his Machinedramon acting as the final boss]].
475*** ''VideoGame/DigimonWorld2'': [[spoiler:[=OverLord=] GAIA, a rogue CPU responsible for trapping everyone in the Digital World, as well as creating Chaos Lord, who seeks to become the ultimate being]].
476*** ''VideoGame/DigimonWorld3'' initially had a BigBadEnsemble between the Leader of the A.o.A terrorists, [[spoiler:the MAGAMI president]], and [[spoiler:Lord Megadeath]] until [[spoiler:Snatchmon, a combination of various Vemmon, performed a DragonAscendant and merged with the Gunslinger Satellite to digivolve into Galacticmon with intentions of merging with ''Earth'' itself to become [[EldritchAbomination Gaiamon]]]].
477*** ''VideoGame/DigimonWorldNextOrder'': [[spoiler:Analogman returns; possessing Tsuzuki and using him]] to spread the Machinedramon plague, create the BH Virus, and spread it to the Digimon in Floatia in order to tear down the walls of the parallel worlds and sow chaos.
478** ''Digimon Story'' series:
479*** ''VideoGame/DigimonWorldDS'': [[spoiler:Alphamon, who wants to destroy all humans under the belief that they're a danger to Digimon; with his plans inadvertently awakening Chronomon]].
480*** ''VideoGame/DigimonStoryCyberSleuth'': The biggest threat are the Eaters. Their mere existence is responsible for [[spoiler:bringing in the other primary threat, the Royal Knights led by Duftmon and Crusadermon, particularly the latter, as her schemes drive the game's first half in her guise as Kishibe/CEO of Kamishiro. Suedou is the third contender for Big Bad, as he too is driven by the existence of the Eaters for his distinct antagonistic agenda and ultimately wins TheBigBadShuffle between the three forces by merging with Mother Eater to manipulate reality to his own ends]].
481** ''VideoGame/DigimonWorldDataSquad'': Lucemon, TheManBehindTheMan to Tsukasa Kagura and Creepymon; as well as the creator of the Demon Lords. He uses them as a means of reviving himself so he may engulf the world in the [[EldritchLocation Dark Arena]].
482** ''VideoGame/DigimonSurvive'': The Master, an enigmatic being that the Kenzoku serve; whom he has sacrifice any human child that wanders into their world for the purpose of saving it.
483* ''Franchise/{{Disgaea}}'':
484** ''VideoGame/DisgaeaHourOfDarkness'' has [[KnightTemplar Vulcanus]], who wants to destroy all demons, along with anyone and anything that tries to defend them.
485*** ''VideoGame/DisgaeaD2ABrighterDarkness'' has [[spoiler:Xenolith]], with all of the major events of the game being traced back to him absorbing the Netherworld's magic and kidnapping the angels.
486** ''VideoGame/Disgaea2CursedMemories'' has [[spoiler:the fake]] Overlord Zenon. Adell and the rest of the group are pursuing him in order to end the curse on Veldime or get revenge, respectively.
487** ''VideoGame/Disgaea3AbsenceOfJustice'' has [[spoiler:[[FallenHero Geoffrey/Super Hero Aurum]], who's been grooming Mao to be a powerful overlord that he can take down]].
488** ''VideoGame/Disgaea4APromiseUnforgotten'' has [[spoiler:Judge Nemo]], the one behind the Netherworld's decline
489** ''VideoGame/Disgaea5AllianceOfVengeance'' has Void Dark, the leader of the Lost who's hell-bent on taking over all the Netherworlds in his path.
490** ''VideoGame/Disgaea6DefianceOfDestiny'' initially has the God of Destruction, [[spoiler:who is actually Zed's younger sister Bieko forcefully transformed by Cerberus, who is secretly the Super Sage Misual]].
491* ''Franchise/{{Dishonored}}'':
492** ''VideoGame/{{Dishonored}}'': [[AristocratsAreEvil Lord Regent Hiram Burrows]], who hired Daud to assassinate the Empress, had Corvo framed for the murder, and usurped control of the Empire for himself. He's later revealed to be the cause of the Plague, as well. [[spoiler:[[MeetTheNewBoss Admiral Farley Havelock]] takes over the role after his downfall.]]
493** ''VideoGame/Dishonored2'': [[TheUsurper Delilah Copperspoon]], who took over the Empire from Emily and plans to use her magic to remake the world how she sees fit.
494** ''VideoGame/DishonoredDeathOfTheOutsider'': [[TheCorrupter The Outsider]], who Billie Lurk sets out to track down and kill.
495* ''VideoGame/Disintegration2020'': Black Shuck, the leader of the Rayonne forces in the game's region. He's the one gunning for Romer Shoal and his crew, and he's directly or indirectly responsible for all the carnage the Rayonne cause in the game.
496* ''VideoGame/DivineDivinity'': The Demon of Lies [[spoiler:a.k.a. Duke Janus]], who aims to bring the Lord of Chaos to Rivellon.
497** ''VideoGame/BeyondDivinity'': Samual, the demon lord who soul-forges the Paladin with the Death Knight.
498** ''VideoGame/DivinityIITheDragonKnightSaga'': Damian, [[spoiler: although Ygerna is the one who corrupted him, and Ygerna becomes the DragonInChief in ''Flames of Vengeance'']].
499** ''VideoGame/DivinityDragonCommander'': [[spoiler:Corvus the demon is responsible for every unpleasant event of the protagonist's life. Played with in that Corvus himself was defeated and bound prior to the events of the game, and the game itself is spent dealing with the mess his advanced technology and behind-the-scenes influence has made of the kingdom]].
500** ''VideoGame/DivinityOriginalSin'': [[spoiler:Leandra, the sister of Icara the White Witch]].
501** ''VideoGame/DivinityOriginalSinII'': Bishop Alexander [[spoiler:at first, but it later turns out to be Dallis the Hammer. In the end, however, it's a BigBadDuumvirate between Bacchus Rex and the God King]].
502* ''VideoGame/DoItForMe'': The Wuffles/Wooffles are black monsters that are terrorizing the protagonist's girlfriend and who he must kill to prove his love for her. [[spoiler:[[DiscOneFinalBoss However]], they're actually [[HumanAllAlong innocent classmates]]- the real villain is [[LoveInterestTraitor the girlfriend]], who tries to manipulate the protagonist into killing the students for her own amusement.]]
503* ''VideoGame/DontBeAfraid'' has Franklin Deagon, a masked SerialKiller who preys upon children and is the one who kidnapped David.
504* ''Franchise/{{Doom}}'':
505** ''VideoGame/{{Doom}}'': The [[BrainInAJar Spiderdemon]] is behind the invasions of Phobos and Deimos, and fighting through Hell to defeat him is the final goal of the game.
506** ''VideoGame/DoomIIHellOnEarth'': [[MookMaker The Icon of Sin]] is the one who spawned all the enemies in the first place. Considering that it only appears once in the game, and its destruction damages ''untold miles'' of Hell's surface, we can assume that it is the big bad of the game.
507** ''VideoGame/Doom64'': The [[EvilMatriarch Mother Demon]] is the one who rebuilds the demon army to attack humanity once more.
508** ''VideoGame/Doom3'': Dr. Malcolm Betruger, who is singlehandedly responsible for the demon invasion of Mars, is both a MadScientist and an EvilSorcerer in league with Hell itself, and wants to bring about HellOnEarth. [[spoiler:He becomes a demonic dragon thing by the name of the Maledict at the end of the game proper, and you finally put paid to the evil bastard in ''Resurrection of Evil''.]]
509** ''VideoGame/Doom2016'' [[MadScientist Olivia Pierce]] colludes with Hell in bringing about [[HellOnEarth Hell on Mars]], and eventually [[spoiler:becomes the Spider Mastermind in a bid to become a God]].
510** ''VideoGame/DoomEternal'':
511*** [[AngelicAbomination The Khan Maykr]] is the ruler of the Makyrs of Urdak and overseer of the [[HellOnEarth demonic invasion of Earth]], having made a [[DealWithTheDevil deal with Hell]] to give over worlds and their people to be consumed by the demons in exchange for the Argent Energy that her own people need to survive.
512*** ''The Ancient Gods'' two-part expansion has the Dark Lord, Davoth, the ruler of Hell and leader of its armies.
513* ''VideoGame/DonPachi'' series:
514** ''[=DoDonPachi=]'': [[spoiler:Colonel Longhena, who organized the Element Dolls' attack on mankind that lead to humanity's near extinction and manipulated the Pilot into destroying the lost fleet of the DonPachi Corps.]].
515** ''[=DoDonPachi DaiOuJou=]'': Hibachi, being the leader of the mechanized hordes looking to eradicate humanity and the cause of the Blissful Death Wars.
516** ''[=DoDonPachi SaiDaiOuJou=]'': [[spoiler:Hina, a.k.a. Hibachi/Inbachi, who wishes to eradicate humanity and make way for the "evolution" that is her and the Element Dolls.]]
517%%* ''VideoGame/DoubleDragon'':
518%%** Willy Mackey in the arcade original and most remakes of it, as well as the arcade version of ''VideoGame/DoubleDragonII''.
519%%** [[CainAndAbel Jimmy Lee]] in the NES version of the first game.
520%%** [[MasterOfIllusion The Mysterious Warrior]] in the NES and PC Engine CD versions of ''VideoGame/DoubleDragonII''.
521%%** [[spoiler: [[TreacherousAdvisor Hiruko]]]] in ''The Sacred Stones''.
522%%** Duke in ''Return''.
523%%** [[EvilUncle The Shadow Master]] in the [[WesternAnimation/DoubleDragon1993 animated series]] as well as its adaptation ''The Shadow Falls''.
524%%** Koga Shuko in [[Film/DoubleDragon1994 the movie]] and its video game adaptation.
525%%** [[DemBones Skullmageddon]] in ''VideoGame/DoubleDragonNeon''.
526%%** [[BigBadDuumvirate Casey and Shannon Okada]] in ''VideoGame/DoubleDragonIV''.
527* ''VideoGame/DoublePugSwitch'' gives us Sker, a cat who pilots its own personal ship, and is always shooting missiles at [[PlayerCharacter Otis]] when they encounter one another.
528* ''VideoGame/DragaliaLost'': For the first half of the main campaign, Morsayati fills this role, as they are the one who has kidnapped [[DamselInDistress Zethia]] and are the tyrant who is leading Alberia into chaos. [[spoiler: For most of the second half, [[EvilTwin Nedrick]] takes on the role, as he has kidnapped Zethia and his men, the Agito, are the ones antagonizing the heroes after Morsayati’s defeat. Eventually Xenos is revealed to be the true Big Bad of the entire game, as he acts as the FinalBoss and was the one responsible for all the horrible things that have happened thus far.]]
529* ''Franchise/DragonAge'':
530** ''VideoGame/DragonAgeOrigins'' has [[WellIntentionedExtremist Loghain]], whose actions directly worsen Ferelden's chances of surviving the Blight, and [[GenericDoomsdayVillain the Archdemon]], who leads the Darkspawn and is ''causing'' the Blight to happen.
531** ''VideoGame/DragonAgeOriginsAwakening'' has [[TragicMonster the Mother]].
532** ''VideoGame/DragonAgeII'' deconstructs this trope. While [[spoiler:[[KnightTemplar Meredith]]]] is the FinalBoss, in the end, every party involved in the game's climax is partly to blame for how things turn out, whether by design or simply being a bit too close to the fire. Cassandra tries to find out who the BigBad was, but there is only GreyAndGrayMorality and WellIntentionedExtremist characters.
533** ''VideoGame/DragonAgeInquisition'' has [[AGodAmI the Elder One]] a.k.a. [[spoiler:Corypheus]].
534* ''VideoGame/DragonForceSega'': Madruk, a wicked god bent on destroying both Legendra and the Gods.
535* The ''Franchise/DragonQuest'' games have their fair share of Big Bads:
536** ''VideoGame/DragonQuestI'' has the [[EvilOverlord Dragonlord]]. He's the supreme being over all monsterkind who has stolen the Sphere of Light, planted himself in Castle Charlock and has subjugated the entire world to his will.
537** ''VideoGame/DragonQuestII'' had [[EvilSorcerer Hargon]], who attacks Moonbrooke and [[spoiler:summons Malroth upon his defeat]].
538** ''VideoGame/DragonQuestIII'' had [[spoiler:Zoma]], who was plunging the world of Alefgard into darkness while [[spoiler:his minion Baramos ruined another world at his behest]].
539** ''VideoGame/DragonQuestIV'' had Psaro the Manslayer, aka Necrosaro [[spoiler:until the DS version added a new chapter, revealing that Psaro's apparent [[TheDragon Dragon]] Aamon had in fact been manipulating him all along]].
540** ''VideoGame/DragonQuestV'' had Nimzo (also known as Mildrath), the human who perfected the Secret of Evolution to transform himself into a a demon god and who is looking for a way to break out of the Underworld.
541** ''VideoGame/DragonQuestVI'' had Murdaw, also known as Mudo [[spoiler:until his defeat, upon which you find out evil still plagues the world. After D(h)uran is defeated, he tells them that he, Murdaw/Mudo, and the other demon lords were just pawns of the true Big Bad, Mortamor (also known as Dethtamoor)]].
542** ''VideoGame/DragonQuestVII'' had Orgodemir, the Demon Lord who sealed most of the continents of the world to prevent God from defeating him. [[spoiler:In the second disk, he tries to seal the continents again, while posing as God Himself.]]
543** ''VideoGame/DragonQuestVIII'' had [[VillainousHarlequin Dhoulmagus]] until it turns out [[spoiler:the scepter he stole had been containing the real BigBad, Lord Rhapthorne]].
544** ''VideoGame/DragonQuestIX'' had [[spoiler:[[FallenAngel Corvus]], a former [[OurAngelsAreDifferent Celestrian]] driven mad by centuries of hatred and solitude]].
545** ''VideoGame/DragonQuestXI'' had Mordegon, an EvilSorceror who was [[spoiler: a former hero who got corrupted by [[GreaterScopeVillain Calasmos]]]].
546* ''VideoGame/DrakeOfThe99Dragons'': [[CorruptCorporateExecutive Tang]], CEO of Tang Industries, is the one behind the massacre of Drake's clan who aims to free the [[GreaterScopeVillain Spirit King Supreme]] and TakeOverTheWorld.
547%%* The ''Franchise/{{Drakengard}}'' series has Big Bads for each installment. Basically, all of them are messed up ([[DysfunctionJunction as are most characters]]), and not all problems are strictly their fault:
548%%** In ''VideoGame/{{Drakengard}}'', it's [[spoiler: Manah, with the Watchers as the GreaterScopeVillain]].
549%%** In ''VideoGame/Drakengard2'', it seems to be [[spoiler: [[RogueProtagonist Caim]]]] but is actually [[spoiler:Gismor]].
550%%** In {{spinoff}} game ''VideoGame/NieR'', it is The Shadowlord, [[spoiler: except it's actually Devola and Popola, who are also sort of the BigGood]].
551%%** In ''VideoGame/Drakengard3'', it is apparently [[VillainProtagonist Zero]] but is actually [[spoiler:[[TheDogWasTheMastermind The Black Flower]]]].
552%%** In ''VideoGame/NierAutomata'', the sequel to ''[=NieR=]'', the BigBad seems to be [[spoiler: Adam and Eve, particularly the latter]], but [[spoiler: 9S [[SanitySlippage becomes villainous]]]] as the story goes on, though the true villains are [[spoiler: N2 (Terminal α and Terminal β)]].
553* ''VideoGame/{{Dropsy}}'': [[CorruptCorporateExecutive The S-Corporation CEO]], Dropsy's wicked older brother who's responsible for the circus fire that the town blames him for and attempts to kill Dropsy [[spoiler:to ensure that he's the only heir to the throne of his species]].
554* In ''VideoGame/DungeonMakerIITheHiddenWar'', the BigBad is Revenger, a demon looking to restart a 70,000-year-old war that almost destroyed the world.
555* ''VideoGame/{{Dusk}}'': [[spoiler:Nyarlathotep, the true mastermind behind the cult corrupting Dusk]].
556* ''VideoGame/DrawnToLife'' and it's sequel has Wilfre, a corrupted Raposa who destroyed the book of life and brought the shadows to the world in the first game, and started draining the world's color in the second game.
557** ''Drawn to Life: The Next Chapter'' for the Wii has [[spoiler: Circi, a Raposa in love with Wilfre who seeks his resurrection]].
558* ''VideoGame/{{DRL}}'' has the spider mastermind. [[spoiler:And behind her, the true evil behind the invasion, John Carmack.]]
559* ''VideoGame/DustAnElysianTail'' has General Gaius, who leads the campaign to wipe out the reptilian Moonblood race.
560* ''VideoGame/DyingLight'': Kadir "Rais" Suleiman, the leader of a brutal gang of survivors who hoard supplies and Antizen to exploit other survivors.
561[[/folder]]
562
563[[folder:E]]
564* ''VideoGame/EarthwormJim'': [[GodSaveUsFromTheQueen Queen Slug-For-A-Butt]], who seeks to destroy Earthworm Jim and reclaim the Super Suit, while trying to take over the universe.
565* ''VideoGame/EcoFighters'': Kernal Goyolk is the president of Goyolk K.K. who seeks to exploit Planet Elwood to line his pockets, having reduced other planets into dread spheres.
566* ''VideoGame/EldenRing'': While the game doesn't really have one story-spanning antagonist, [[BigBadEnsemble several villainous factions and leaders of said factions]] are vying for the fate of the Lands Between:
567** The two of the most malicious Demigods, Praetor Rykard and Mohh the Lord of Blood, definitely count. The former has turned himself into an AnimalisticAbomination in an attempt to become powerful enough to devour the gods, driving him into hedonistic and hunger-driven immortal being who dreams of [[OmnicidalManiac devouring the world itself]], while Mohg is a mad SatanicArchetype who leads a cult of serial killers and brainwashed slaves, is attempting to ascend to god-hood by [[spoiler:attempting to corrupt his half-brother Miquella and take him as his divine consort]]. Either of them would fit as the big bads of any other RPG, but here they're mere optional stepping stones for the Tarnished and [[BigBadWannabe Big Bad Wannabes]] (altough Rykard far less so than Mohg).
568** The [[SentientCosmicForce Outer God of Frenzied Flame]], alongside its MouthOfSauron the Three Fingers and its apostle Shabriri, are attempting to create a lord that will scour the world of all life and fuse it back into one in an AssimilationPlot - however, unlike the other antagonists, they actually require the player character to help them.
569** The God of Scarlet Rot is an [[GreaterScopeVillain unseen]] [[EldritchAbomination Outer God]] who seeks to spread its malevolent disease throughout the Lands Between and consume everything and everyone - ironically, its chosen vessel, Malenia, is not this trope at all, as she has no ambitions or desire to become the Goddess of Rot or claim the Elden Ring for herself. However, she's still a dangerous ticking time bomb, as her sheer presence passively spreads the Rot (as can be seen in the Haligtree) and it's only a matter of time until she loses herself.
570** [[spoiler:Marika]] is the cause of the shattering of the Elden Ring, and everything that followed, [[spoiler:and though she remains unfought, her 'husband'/other half Radagon is also responsible for sealing the Erdtree and preventing anyone from becoming Elden Lord, which forces the Tarnished to unleash Destined Death to open a path to Marika]].
571* ''Franchise/TheElderScrolls'' has a different BigBad in each game, though each often serves or is at least in league with one of the series' [[OurGodsAreDifferent many deities]], often a Daedric Prince. To note:
572** ''[[VideoGame/TheElderScrollsArena Arena]]'' has the [[EvilChancellor traitorous]] [[CourtMage Imperial Battlemage]] and EvilSorcerer classic Jagar Tharn in this role. Later works reveal that Tharn was secretly in league with [[OmnicidalManiac Mehrunes Dagon]], the Daedric Prince of [[DestroyerDeity Destruction]].
573** ''[[VideoGame/AnElderScrollsLegendBattlespire Battlespire]]'', a DungeonCrawling spin-off game taking place during ''Arena'''s time period, has Mehrunes Dagon himself leading the [[TheLegionsOfHell Daedric invasion]] of the [[WizardingSchool Imperial Battlespire]].
574** ''[[VideoGame/TheElderScrollsIIDaggerfall Daggerfall]]'' plays with it, having several plot relevant faction leaders without having a true Big Bad. Lord Woodborne [[spoiler:turns out to have been the one to murder the King of Daggerfall, kicking off the game's main quest]], but doesn't fit the role once the plot gets going. The Underking is the being most directly tied to the main quest and certainly looks the part of an evil villain, but [[spoiler:as it turns out, is not all that far from being a ''good guy'']]. Out of all of the faction leaders who can get what they want in the game's MultipleEndings, Mannimarco is the most malevolent and villainous in terms of his intentions, but still isn't a true Big Bad.
575** ''[[VideoGame/TheElderScrollsAdventuresRedguard Redguard]]'', a ActionAdventure spin-off game which tells a smaller-scale, more personal story, has the corrupt Imperial governor Admiral Richton as the main antagonist.
576** ''[[VideoGame/TheElderScrollsIIIMorrowind Morrowind]]'' has the PhysicalGod supervillain Dagoth Ur in this role. Depending on your interpretation of events leading up to and following the events of the game, [[spoiler:Azura, the Daedric Prince of Dawn and Dusk, may be either a BigGood for her role in defeating Dagoth Ur or a GreaterScopeVillain and ManipulativeBastard who manipulated these events to her own ends, ending up as a VillainWithGoodPublicity to the Dunmer people in the end]].
577*** The ''Tribunal'' expansion has [[spoiler:Almalexia, one of the Tribunal {{Physical God}}s who, as a result of losing her divinity due to the events of the main game, [[GoMadFromTheRevelation goes completely insane]] and AxeCrazy]].
578*** The ''Bloodmoon'' expansion has Hircine, the Daedric Prince of the Hunt. The plot of the expansion is essentially him finding the [[HuntingTheMostDangerousGame most worthy competitors]] for his legendary hunt.
579** ''[[VideoGame/TheElderScrollsIVOblivion Oblivion]]'' has Mehrunes Dagon once again. Mythic Dawn cult leader Mankar Camoran serves as his [[TheDragon Dragon]] and [[TheHeavy Heavy]] for the main quest, with Dagon himself only showing up at the very end.
580*** The ''Knights of the Nine'' expansion has the resurrected [[AbusivePrecursors Ayleid]] lord Umaril the Unfeathered, with the Daedric Prince Meridia as his [[GreaterScopeVillain divine backer]].
581*** The ''Shivering Isles'' expansion has Jyggalag, the Daedric Prince of [[ControlFreak Order]] and [[spoiler:alter-ego of [[BigGood Sheogorath]], Daedric Prince of [[MadGod Madness]]]].
582** ''[[VideoGame/TheElderScrollsVSkyrim Skyrim]]'' has [[EvilGod Alduin]], the colossal black dragon BeastOfTheApocalypse. The secondary main plot will have either [[FourStarBadass Imperial General Tullius]] or [[RebelLeader Stormcloak leader Ulfric Stormcloak]] in this role depending on which side you choose to support. In either case, the [[AntiHumanAlliance Aldmeri]] [[ANaziByAnyOtherName Dominion]] is the GreaterScopeVillain to either side, with each having different opinions of the best way to deal with them in the inevitable second Great War.
583*** The ''Dawnguard'' DLC has [[VampireMonarch Lord Harkon]], the leader of the Volkihar [[OurVampiresAreDifferent vampire]] clan.
584*** The ''Dragonborn'' DLC has Miraak, the [[EvilCounterpart First Dragonborn]]. He is in service to the Daedric Prince Hermaeus Mora, who serves as a GreaterScopeVillain [[spoiler:and [[TheBadGuyWins gets exactly what he wants]] in the end]].
585** ''[[VideoGame/TheElderScrollsOnline Online]]'' has Molag Bal, the Daedric Prince of [[TheCorrupter Corruption]] and Domination, in this role.
586** ''[[VideoGame/TheElderScrollsBlades Blades]]'' has Celemaril [[LightIsNotGood Light-Bringer]], and ancient SorcerousOverlord who was inadvertently [[SealedEvilInACan unsealed from his tomb]].
587* ''VideoGame/ElevatorRitual'': [[spoiler:Professor Kumozoru]] is the one who turned everyone in the Rainbow Hotel into monsters [[spoiler:with his formula]] and is the FinalBoss who Naysilla must defeat before she can return to her world.
588* ''VideoGame/ElliotAndTheMusicalJourney'' has the Skeleton King, who's kidnapped Princess Adeline, and stolen the world's music.
589* ''VideoGame/ElseHeartbreak'' has [[spoiler:The Ministry, who want to regulate use of Modifiers]].
590* ''VideoGame/EmbricOfWulfhammersCastle'': [[spoiler:[[HotAsHell Azreala D'Fleur]]/Tierra del Fuego]] is revealed in the Final Ending as the one behind all the villains the Duchess has faced, as [[spoiler:the events are the Duchess dreaming of the future, but Azraela is influencing the dreams to feed on her despair]].
591* ''VideoGame/EmeraldCityConfidential'': [[CardCarryingVillain The First and Foremost Phanfasm]], who Petra must stop from plunging Oz into war once again, [[spoiler:as well as save her brother from his clutches.]]
592* ''VideoGame/EmeraldDragon'': The Demon King Galshia [[spoiler:fits this for most of the game, but he's later revealed to working for the true Big Bad, Tiridates]].
593* ''VideoGame/EndRoll'': [[spoiler:The Indecent One]] is the source of the monsters in Russell’s dream, and his biggest tormentor. [[spoiler:She represents Russell’s [[AbusiveParents abusive mother]].]]
594* Every ''VideoGame/EpicBattleFantasy'' game after the second[[note]]The final boss of the first game is just another, bigger monster fought, while the final boss of the second is a WellIntentionedExtremist trying to take over the world with no affiliation with any of the previous enemies[[/note]] has a major villain behind the events of the game:
595** ''VideoGame/EpicBattleFantasy3'': Akron, a demonic being accidentally freed by the heroes poking him with their weapons. His awakening creates a black hole around him and disturbs the surrounding area.
596** ''VideoGame/EpicBattleFantasy4'': [[spoiler:Godcat is the one behind the events of the game, getting a group of Cats to steal the three jewels to revive her so she can wipe out humanity. She is also revealed to have created Akron]].
597** ''VideoGame/EpicBattleFantasy5'': [[spoiler:The Devourer, the creator of the entire ''Epic Battle Fantasy'' universe, kicks off the plot by being fed up with the party's free will and sending Cosmic Monoliths to observe them. The dark energy from the Cosmic Monoliths corrupts the land around them and makes the wildlife hostile, indirectly causing most of the enemies to fight the party and most of the conflict in the game. It is at a higher order than Godcat or Akron and is in fact the creator of the former]].
598* ''VideoGame/EpicSeven'' has one per Episode.
599** Episode One, ''The Heir of the Covenant'', focuses on Anghraf the Archdemon, the being responsible for destroying the world ''six times.''
600** Episode Two, ''Godkiller'', features Straze, the BlackKnight and [[AntagonistTitle titular Godkiller]], [[spoiler:until it's revealed that he is having his strings pulled by Faustus, the Dark Star and the main villain for the entire story.]]
601** Episode Three, ''Hymn of a Wailing Tundra'', primarily has Mortelix the Great One in the spotlight as the most powerful dragon of all, seeking to find a WorthyOpponent. [[spoiler: The real mastermind behind all the wars, however, is Belian, Android Ruler of Politia, who wishes to assimilate the power of a dark being known as Tiwig.]]
602* ''VideoGame/EternalRadiance'': Eldareth is the leader of the Shadowborn, an organization that steal Akleim artifacts and assassinates anyone who tries to investigate or obstruct them. [[spoiler:He's not the first leader of the organization, but he is the one ordering the recent thefts and plans to use the artifacts to destroy the Shadowborn while most of them are gathered at their base. This has the risk of destroying all of Darencia, which is why the protagonists have to stop him.]]
603* ''VideoGame/EternalSonata'' has Count Waltz, the ruler of TheEmpire who causes the problems for the heroes with his new drug, the Mineral Drug, which can cure illness, but are addictive and drive humans insane.
604* ''VideoGame/EternalTwilight'' has Black Magi Supreme Azael, who manipulated Empress Verona into starting a war against Magi, all as part of his scheme to eliminate his successor, claim the COSMOS relic, and TakeOverTheWorld.
605* ''VideoGame/EvenForEternia'': Arisu is the source of all Umbra and seeks to use the Calypso to wipe out humanity and Umbra, and then rebuild the world from scratch. To that end, he removes specific memories of the Umbra to ensure that the Calypso shards and a vessel suitable for the Calypso falls into his hands. Later, it turns out his real plan is for Rubellum to be the host of the Calypso and that his vision for the world is actually similar to Rubellum's, but his plans still end up with quite a lot of collateral damage.
606* ''VideoGame/{{Everhood}}'': Gold Pig, the leader of the Mages who rule Everhood, steals Red's arm and Blue Thief's legs, sparking their quest to get them back. Gold Pig is also responsible for a lot of the suffering of the citizens, and [[spoiler:does everything in their power to stop Red from [[MercyKill releasing them]] from being his [[WhoWantsToLiveForever immortal slaves]] once Red gets their arm back to keep everyone]].
607* ''VideoGame/TheEvilWithin'': Ruvik, the enigmatic hooded man responsible for pulling you into his twisted world.
608* ''VideoGame/TheEvilWithin2'': Father Theodore, MOBIUS's head of recruitment who desires Lily's power so he can have complete dominion over STEM. [[spoiler:It was his manipulations and betrayal that caused Myra's corruption.]]
609* ''VideoGame/EVOSearchForEden'' has a new BigBad for each of the five Eras:
610** Era 1: [[StarterVillain King Kuralesache]], the ruler of the sea who wants to prevent the dedizens from discovering the surface world.
611** Era 2: [[SocialDarwinist King Bee]], the leader of the insects. He's later succeeded by [[AvengingTheVillain Queen Bee]], who's out to kill the amphibians as revenge for killing her husband.
612** Era 3: The entire [[TerrifyingTyrannosaur Tyrasaur/Tyrannosaurus species]], who rule the Age of the Dinosaurs.
613** Era 4: [[FeatheredFiend Bird-Man King]] [[BigBadEnsemble and]] [[BigfootSasquatchAndYeti Sir Yeti]], both of whom want to use the Crystal to take over the world.
614** Era 5: [[spoiler:[[UltimateLifeForm Bolbox]], who sends the previous villains to prevent you from entering Eden so that he may enter instead]]. In addition, it turns out the ones accidentally responsible for all of them, except King Kuralesache, are [[spoiler:''Martians'']].
615* ''VideoGame/EyraTheCrowMaiden'': The Infernal King kickstarted the plot of the game by kidnapping the men of [[PlayerCharacter Eyra]]'s tribe.
616[[/folder]]
617
618[[folder:F]]
619* ''VideoGame/{{Fable}}'':
620** ''VideoGame/{{Fable|I}}'': [[MalevolentMaskedMan Jack of Blades]], an ancient demon reawakened after thousands of years who massacred the Hero's village and seeks to conquer all of Albion through the Sword of Aeons.
621** ''VideoGame/FableII'': [[NonActionBigBad Lord Lucien]], who's out to rebuild the Spire, which would grant him his wish to reset the world.
622** ''VideoGame/FableIII'': The Crawler, an EldritchAbomination that desires to spread darkness and death to all corners of the world, and its gaze is now fixed upon Albion.
623** ''VideoGame/FableTheJourney'': [[DarkIsEvil The Corrupter]], an ancient darkness slowly polluting and infecting Albion with his evil.
624* ''Franchise/TheFairlyOddParents'':
625** ''VideoGame/TheFairlyOddparentsBreakinDaRules'': Vicky is the main villain in the console versions, as Timmy has to recover Da Rules book from her and solve the problems Vicky has caused by inadvertently making wishes.
626*** The PC version has Juandissimo as the antagonist, using clouds outside of Timmy's bedroom window to trick Timmy into wishing Da Rules book away, therefore getting Cosmo and Wanda in trouble and risking banishment back to Fairy Academy, where Juandissimo will attempt to get Wanda back from Cosmo.
627*** Anti-Cosmo and Anti-Wanda are behind the conflict in the Game Boy Advance version by using their magic to make Vicky's dreams reality.
628** ''VideoGame/TheFairlyOddParentsShadowShowdown'': [[spoiler:The Chamberlain's Shadow]], who sapped the powers of the all the fairies in Fairy World and schemes to switch the places of humans and shadows.
629** ''VideoGame/FairlyOddParentsClashWithTheAntiWorld'': [[spoiler:Anti-Timmy turns out to be the mastermind behind the anti-fairies' plot to make it Friday the 13th forever]].
630* ''VideoGame/FairyFencerF'' has [[CorruptCorporateExecutive President Hanagata]], the 52-year old leader of [[MegaCorp Dorfa]] who plans to resurrect the Vile God to conquer the world and bring peace. Depending on the route [[spoiler:[[DiscOneFinalBoss however, he’s usurped by a different character]]]]. In the ''Goddess'' Route, he [[spoiler:is killed; Sherman Shallancer becomes the new leader once [[KlingOnPromotion he offs Hanagata]] and goes off the deep end, deciding to fuse with the Vile God himself [[KnightTemplar to bring peace]]]]. In the ''Vile God'' route Hanagata [[spoiler:isn't even the real president, it’s ''[[TheHero Fang]]'', who himself is just a figurehead for Marianna, [[TheManInFrontOfTheMan one of the Four Heavenly Czars]]]]. In the ''Evil Goddess'' route, Dorfa [[spoiler:isn’t even a threat anymore as it’s been disbanded, and there is a new organization, the Septerion Club, ruled by Jeane/Junown, who wants to revive the titular Evil Goddess]].
631* ''VideoGame/FaithTheUnholyTrilogy'': The first two chapters has the demon only known as the UNSPEAKABLE. In Chapter I, it is possessing Amy Martin, whom John Ward is trying to exorcise. In Chapter II, it traps John in a nightmare and disguises itself as Miriam Bell, and John must beat it to escape. Chapter III meanwhile, has Gary Miller, the leader of the Eternal Order of the Second Death, aims to provide his master, the UNSPEAKABLE, with a vessel so it can bring about TheEndOfTheWorldAsWeKnowIt.
632* The ''Franchise/{{Fallout}}'' series:
633** ''VideoGame/Fallout1'': TheMaster, the leader of the Unity who wants to turn everyone into super mutants and kill anyone who opposes him.
634** ''VideoGame/Fallout2'': Dick Richardson, [[PresidentEvil the President of the Enclave]], with his Secret Service agent Frank Horrigan as the DragonInChief.
635** ''VideoGame/FalloutTacticsBrotherhoodOfSteel'': The Calculator, an ArtificialIntelligence in charge of Vault 0 in Cheyenne Mountain and the leader of the robot army.
636** ''VideoGame/FalloutBrotherhoodOfSteel'': Attis, a highly intelligent super mutant commander in the Master's Army who wants to continue his plans.
637** The cancelled ''VideoGame/FalloutVanBuren'': Dr. Victor Presper, an EvilutionaryBiologist who plans to nuke the Earth using the orbital space station B.O.M.B.-001.
638** ''VideoGame/Fallout3'': President John Henry Eden of the Enclave, with Colonel Autumn as TheHeavy.
639** ''VideoGame/FalloutNewVegas'': Caesar[[note]]a little trickier since there's an ending path where you join him, but he's still obviously the central figure in the main conflict, and siding with him merely makes your character a VillainProtagonist[[/note]], with Legate Lanius as TheDragon, who becomes the DragonAscendant should you kill Caesar and is the FinalBoss of three out of four endings. Aside from Caesar, the {{D|ownloadableContent}}LCs all have their own Big Bads:
640*** ''Dead Money'': Father Elijah, the former Elder of the Mojave chapter of the Brotherhood of Steel who puts [[ExplosiveLeash explosive collars]] on you on three others to rob the pre-War Sierra Madre Casino.
641*** ''Honest Hearts'': Salt-Upon-Wounds, war chief of the vicious White Legs tribe who wiped out New Canaan and are now attacking the Dead Horses and Sorrows.
642*** ''Old World Blues'': The insane MadScientist Dr. Mobius, [[spoiler:later on revealed to be Dr. Klein, head of the Think Tank]].
643*** ''Lonesome Road'': The former courier and Legion Frumentarius Ulysses, who is also the GreaterScopeVillain of the [=DLCs=]. He wants to [[spoiler:nuke the New California Republic to take revenge for the Courier unknowingly doing the same to Ulysses's home, the Divide]].
644** ''VideoGame/Fallout4'': "Father", [[spoiler:a.k.a. your son Shaun]], the mysterious leader of the Institute that kills people and replaces them with human-like robots called Synths. Though Elder Maxson can also be an antagonist if you don't ally with the Brotherhood of Steel.
645* ''VideoGame/FancyIsland'': The [[MonsterClown Pieyama God]] is the leader of the monsters who rules over the titular AmusementParkOfDoom.
646* ''VideoGame/{{Fantasian}}'': While it initially seems like Vam the Malevolent in the main villain, given that he's the one who released the Mechtaria in an attempt to prevent the world from being consumed by order, it's soon revealed that Jas is the greater threat, who seeks to destroy the world and remake it with him as its god.
647* ''VideoGame/FantasyMaidensOddHideout'': [[spoiler:Bernd's {{unnamed|Parents}} father]] is the one who is trying to kill Ange and is thus responsible for her being trapped in the [[CrapsaccharineWorld gingerbread house]], [[spoiler:though [[WellIntentionedExtremist he's doing it to protect the village]]- [[VanHelsingHateCrimes it just so happens]] that [[FriendlyNeighborhoodVampire Ange]] is a TragicMonster]].
648* ''Franchise/FarCry'':
649** The [[VideoGame/FarCry1 original game]] has Dr. Krieger, [[spoiler:who is also in a BigBadEnsemble with Harland Doyle]].
650** The [[VideoGame/FarCry2 second game]] The Jackal, an arms dealer selling weapons to both waring factions, APR and UFLL, who you were sent to kill. [[spoiler: Subverted as he turns out to be one of the good guys (if you can call it that), and by the end of the game you work with him to combat the factions, led by Nick Greaves and Hector Voorhees respectively, which team up by the games climax and intend to commit genocide on the civilians.]]
651** The [[VideoGame/FarCry3 third game]] it looks to be Vaas Montenegro, [[spoiler: but it's really [[CorruptCorporateExecutive Hoyt Volker]]]].
652*** ''[[VideoGame/FarCry3BloodDragon Blood Dragon]]'' has Ike Sloan.
653** [[VideoGame/FarCry4 The fourth game]] has Pagan Min, [[spoiler: but it's not like [[LaResistance Golden Path]] leaders Amita and Sabal are any better, in fact the ending shows us they may be worse]].
654** ''[[VideoGame/FarCryPrimal Far Cry: Primal]]'' has Ull, leader of the cannibalistic Udam tribe, [[BigBadEnsemble and]] Batari, leader of the slave-taking, sun-worshipping Izila tribe.
655** ''VideoGame/FarCry5'' has Joseph Seed, "The Father", head of the Project at Eden's Gate.
656*** ''VideoGame/FarCryNewDawn'' has [[BigBadDuumvirate Mickey and Lou]], leaders of the Highwaymen, [[BigBadEnsemble and]] Ethan Seed, the leader of New Eden, the successor to the Project at Eden's Gate. Joseph is still around, but he’s not nearly as much of a threat as these three are.
657* ''VideoGame/FatalFury'' has [[Characters/FatalFuryGeeseHoward Geese Howard]], the ArchEnemy of series hero Terry Bogard and his brother Andy for murdering their father and the one behind the King of Fighters tournament.
658* ''VideoGame/FateGrandOrder'':
659** ''Observer on Timeless Temple'': The one who bombed the command room of Chaldea, [[spoiler:your supposed ally, Professor Lev Lainur Flauros AKA Demon God Flauros]], is set up as the BigBad [[spoiler:despite mentioning early on that he was sent by "our King" to incinerate the planet]] only to get [[spoiler:sliced in half by Altera in Rome. The true mastermind is King Solomon, who commands all 72 Demon God Pillars… except he turns out to be the King of all Demon Gods, Beast I: Goetia, who has hijacked Solomon's body, and the real Solomon is actually the BigGood, Dr. Romani Archaman]].
660** ''Arcade'': [[spoiler:In this timeline, Queen Draco (Beast VI), Mother of Harlots, has replaced Goetia in the role of summoning Demon Pillars to do her bidding]].
661** ''Epic of Remnant'': [[spoiler:Four Demon God Pillars who escaped during the protagonist's final battle with Goetia. By order of Pseudo-Singularity, they are Bael in Shinjuku, [[BigBadDuumvirate working with James Moriarty,]] Zepar in SE.RA.PH. until he is usurped by Kiara, Phenex in Agartha, [[BigBadDuumvirate working with Scheherazade,]] and Räum in Salem until he summons an Outer God named Sut-Typhon (implied to be Yog-Sothoth) that uses Abigail Williams as a vessel]]. The only ArcVillain that isn't a Demon God Pillar is [[spoiler:Sorceror Amakusa Shiro Tokisada in Shimousa, but he's being manipulated by the Caster of Limbo, Ashiya Douman]].
662** ''Cosmos in the Lostbelt'': [[spoiler: The Foreign God, who serves as the GreaterScopeVillain for all the other stories before finally taking center stage in this saga. Kirschtaria Wodime is TheHeavy for five out of seven Lostbelts, only to meet his end during the events of the fifth one as the Foreign God descends upon the world using its unwitting ultimate Disciple - a resurrected Olga Marie Animusphere - as its host body: U-Olga Marie. In the final Lostbelt, the Foreign God's secret identity is revealed to be that of the Foreign World itself, CHALDEAS, the global environmental sphere model that has been an integral part of Chaldea all this time]].
663** ''Ordeal Call'': [[spoiler:The Foreign God CHALDEAS remains out of reach, though it is still the driving force behind the plot. Its vessel U-Olga Marie is revived and split by Count Alessandro di Cagliostro - a Disciple of CHALDEAS - into four Elemental Derivatives, the E-Olga Marie Lostbits, all of whom form a BigBadEnsemble as they are not exactly loyal to it or each other, though the E-Olga Marie of Joy is stated by E-Aqua Marie (who represents Comfort) to be an awful monster far beyond the others.]] Meanwhile, the Ordeal Call singularities each have their own ArcVillain, Paper Moon featuring [[spoiler:Rani XIII and her Archer Durga (who becomes Kali, the FinalBoss)]] while Id has a different version of [[spoiler:Edmond Dantès, Le Comte de Monte Cristo]]. [[spoiler:Cagliostro]] attempts to one-up him, but [[spoiler:he gets outplayed by Edmond and ends up being more of a PostFinalBoss]].
664* ''VideoGame/FearEffect'': Yim Lau Wong, the Chinese King of Hell who plans to use Wee to kickstart the apocalypse.
665* ''VideoGame/FightingForce'': Zeng, who plunged the world into chaos just to fulfill a prediction of the world ending.
666* ''VideoGame/FinalFight'':
667** First game: Belger, the leader of the Mad Gear gang who arranged Jessica's kidnapping and is responsible for most of the ills that plague Metro City.
668** ''2'': Retu, the new leader of the Mad Gear gang who's responsible for kidnapping Rena and Genryusai.
669** ''3'': Black, the leader of the Skull Cross Gang who has taken over Metro City's criminal underworld.
670** ''Streetwise'': Father Bella, who masterminded the GLOW outbreak in Metro City so he may take it over and become its savior.
671* For the ''[[VideoGame/FirstEncounterAssaultRecon FEAR]]'' series, it's a toss-up between humongously powerful psychic StringyHairedGhostGirl Alma, telepathic psychopath and [[spoiler:son of Alma]] Paxton Fettel, and CorruptCorporateExecutive Genevieve Aristide. While Alma has undeniably been wronged, her revenge is... [[MindRape rather extreme]]. Fettel, as revealed by the end of the third game, [[spoiler: plans to consume Alma's power in order to take over the world]]. As for Aristide, she just wants to keep her job, and to hell with anyone who has to die in order for her to do so. Events would never have gotten as hellish as they did if any one of them wasn't in the picture. For the first game and its expansions at least, Paxton Fettel is undeniably the main antagonist: he's the one controlling all the Replica soldiers and directing them in an effort to free Alma.
672* The ''Franchise/FireEmblem'' series is home to quite a few per game.
673** ''VideoGame/FireEmblemShadowDragonAndTheBladeOfLight'' and ''VideoGame/FireEmblemMysteryOfTheEmblem'' and their remakes have the BigBadDuumvirate of the Earth Dragon Medeus, and the Dark Pontifex Gharnef.
674** ''VideoGame/FireEmblemGaiden'' and its remake ''Echoes: Shadows of Valentia'':
675*** For the majority of the games, the main villain is Rudolf, TheEmperor of Rigel who wants to TakeOverTheWorld [[spoiler:or so he claims; in actuality, he wants to create a Valentia free of the influence of the degenerating Mila and Duma, and engineered the war so that [[SecretTestOfCharacter his heir, Albein Alm Rudolf II, and Princess Anthiese/Celica of Zofia will rise to kill him and gain the necessary strength to defeat Duma]]]].
676*** After Rudolf's defeat the main villain is the Fell God, Duma [[spoiler:though he's actually a pretty okay guy; he just has some cosmic-scale sibling rivalry and a wee bit of [[SanitySlippage draconic degeneration]] going on]].
677*** Once Duma is defeated in the main story, [[spoiler:the Creation, a much younger Grima from ''VideoGame/FireEmblemAwakening'',]] takes over as the final villain during the post-game StoryArc of ''Echoes''.
678** ''VideoGame/FireEmblemGenealogyOfTheHolyWar'':
679*** The first generation has Manfroy, HighPriest of the Loptr Church who wants to revive the GodOfEvil Loptous.
680*** During the second half of the game, the main antagonist spot is claimed [[TheEvilPrince the Dark Prince Julius]], Loptous' human vessel. Manfroy is still around as his [[TheDragon Dragon]], though.
681** ''VideoGame/FireEmblemThracia776'', a "midquel" to the two halves of the fourth, has the dark priest Veld, though he's actually Manfroy's second-in-command.
682** ''VideoGame/FireEmblemTheBindingBlade'' has King Zephiel as the Main Villain who seeks to wipe out humanity and return the continent of Elibe to Dragon controlled rule. [[spoiler: Largely as a result of being targeted and nearly killed multiple times by his Jerkass, and highly jealous father King Desmond of Bern. This caused [[WoobieDestroyerofWorlds Zephiel]] to believe that humanity is [[HumansAreBastards Irredemable]] and deserving of extermination.]]
683** ''VideoGame/FireEmblemTheBlazingBlade'' (formerly titled just ''Fire Emblem'' in the English release) first focuses on Lundgren, as he's trying to kill Lyn so he can rightfully ascend to the throne of Caelin, but he's just the villain in Lyn's Tale. In the main story, there's the power-hungry Marquess Darin of Laus at first, [[spoiler:but the true wirepuller is the Dark Druid Nergal; having lost his purpose of reuniting with his lost family[[note]]with heavy implications that Ninian and Nils are his children[[/note]], he now seeks to open the Dragon's Gate so that the dragons beyond may burn the world down.]]
684** ''VideoGame/FireEmblemTheSacredStones'' features the Demon King, Formortiis, as the main enemy. He had been defeated by five heroes centuries ago, but he has been revived due to [[spoiler:Lyon's creation of the Dark Stone from Grado's Sacred Stone]]. He is directly responsible for the invasion of Magvel by Grado, and the appearance of monsters across Magvel. Using the naive Prince Lyon to resurrect and control the corpse his father Emperor Vigarde, to invade the other Magvel Nations, starting with Renais in an attempt to destroy their Sacred Stones which sealed away his body. In Ephraim's route, [[spoiler:Lyon]]'s behavior is much more independent as he willingly serves the Demon King, although it's still implied that he is being influenced and manipulated by the Fomortiis into doing his bidding. in Eirika's route however, Fomortiis is instead in full control of [[spoiler:Lyon's body]], making him in both routes the direct Big Bad of the game.
685** ''VideoGame/FireEmblemPathOfRadiance'' stars Ashnard, king of Daein, as the primary antagonist. He desires a world in which the strong dominate the weak, and he seeks to use Lehran's Medallion to awaken a Dark God and gain power. He is the final boss, and most of the earlier bosses are working for him. This includes the Four Riders, most notably the BlackKnight.
686** ''VideoGame/FireEmblemRadiantDawn'' mainly has Duke Lekian, who masterminds many of the events, but the game is divided into four parts, each part having its own big bad. In Part I, the primary antagonist is Jarod, a Begnion general who seeks to suppress the Dawn Brigade's uprising in Daein. In Part II, it is Lord Ludveck, who wants to displace Queen Elincia as ruler of Crimea. Part III is unique, in that you alternately play as opposing armies; it could be considered Micaiah, or Ike, but it would better be considered Lekain himself, who orchestrated Pelleas' signing of the blood pact and forced him into a war he had no dog in. In part IV, [[spoiler:the true antagonists of the entire Tellius saga are [[EvilAllAlong revealed to be]] Sephiran/Lehran, the seemingly kind [[SinisterMinister priest]] who was [[TheManBehindTheMan manipulating both Ashnard and Lekian]] who is the true Big Bad, and [[GodIsEvil Goddess Ashera]], the evil and [[OrderIsNotGood order-obsessed]] counterpart to Yune ([[GoodAllAlong the supposed Dark God Ashnard wanted]]) who seeks to destroy the world, which she has deemed irredeemable, at the urging of Lehran]].
687** The main villain of ''VideoGame/FireEmblemAwakening'' is Validar, the priest of the ReligionOfEvil for [[GreaterScopeVillain Grima, the fell dragon]] who manipulates the various other {{Arc Villain}}s into ensuring Grima's return. [[spoiler:Once Validar has been killed for good, Grima himself, in possession of the future Avatar's body and having traveled into the past along with Lucina and her friends, takes center stage as he resurrects his past self and prepares to destroy the world as he had done in the future.]]
688** ''VideoGame/FireEmblemFates'' changes who the Big Bad is depending on the route.
689*** On the ''Birthright'' route, TinTyrant Garon is the singular main villain you must defeat, although [[spoiler:his last words hint at a greater evil lurking in the shadows]].
690*** On the ''Conquest'' route, Garon is part of a BigBadEnsemble with HeroAntagonist Ryoma, as you must conquer Hoshido and defeat Ryoma in order to bring the war to a close and then kill Garon to bring peace to the land. [[spoiler:After they're dead, Takumi is resurrected by an unseen greater evil and becomes the FinalBoss, having become hell-bent on killing Corrin and razing Nohr to the ground.]]
691*** On the ''Revelation'' route and for the game overall, [[spoiler: Anankos is responsible for every bad thing that happens in all three routes and is the main enemy who must be destroyed]].
692** ''VideoGame/FireEmblemThreeHouses'' initially sets up a BigBadDuumvirate of the Flame Emperor (who is actually [[spoiler:Edelgard von Hresvelg]]) and Thales, leader of "those who slither in the dark" (who spends much of the game impersonating [[spoiler:Lord Volkhard von Arundel]]). Between the two of them, they're the cause of almost all the bad things the happen in the game, but the truth of the situation is more complicated. Thales is the one who made the Flame Emperor what they are and caused their StartOfDarkness while they serve as his DragonInChief who does most of the work and is the more visible antagonist while he remains hidden in the background (due to being the [[spoiler:Emperor of Adrestia]] while the very existence of "those who slither in the dark" is a secret to most people). However, the Flame Emperor actually hates Thales and [[TheStarscream plans to betray him and his faction as soon as they accomplish their mutual goals]]. Which one takes more prominence depends on the route you pick:
693*** In Azure Moon, [[spoiler:Edelgard]] is the single clear-cut Big Bad for the whole route. [[spoiler:You actually do face and kill Thales in this route, but he dies before her and you never learn his true identity or importance]]. This is ironic since [[spoiler:some of his past deeds that Edelgard had no involvement in are very important to the story of this route, but you don't learn the full truth about them]].
694*** In Verdant Wind and Silver Snow, [[spoiler:Edelgard]] is TheHeavy for most of the route, leaving Thales as the sole villain after their death. However, he's not actually the final boss of either route, as there's one more battle after you fight him. On Verdant Wind, [[spoiler:"those who slither in the dark" succeed in resurrecting the PredecessorVillain Nemesis, who fights you in one last battle alongside TheRemnant of "those who slither"]]. On Silver Snow, [[spoiler:Rhea goes insane from overusing her powers and forces you to MercyKill her (unless you got an A-support with her, in which case she survives)]].
695*** In Crimson Flower, on the other hand, you [[spoiler:side with Edelgard]], so the Big Bad is instead [[spoiler:Archbishop Rhea]], while "those who slither in the dark" are reduced to being defeated offscreen in the epilogue.
696*** In theory, Thales is the closest thing to the game has to a single Big Bad overall and is the only one to be an antagonist on all four routes, but you can make the case that the real "Big Bad" of the game is [[spoiler:the ancient conflict between the Agarthans (the ancestors of those who slither in the dark) and Children of the Goddess (of whom Rhea and her followers are the last), and the CycleOfRevenge between them that has perpetuated to the present day. Almost every problem in the setting is a result of their conflicts, and every route's ending results in those who remain on both sides either dead or having lost their power]].
697** ''VideoGame/FireEmblemEngage'': Sombron is the Fell Dragon, and quite possibly the biggest and baddest villain in the mainline series yet, [[spoiler:considering he summons many of the past final bosses as the Dark Emblems in order to serve him as his puppets, and he's more powerful than all of them. He wants to destroy all opposition across the world and obtain all Emblem Rings so that he may find the Emblem of Foundations]].
698** ''VideoGame/FireEmblemHeroes'' has a different Big Bad for each book.
699*** Book 1 focuses on Veronica, princess of the Emblian Empire, [[spoiler: until her big brother Bruno takes over as the true main villain and reveals that he and Veronica where manipulated by a GreaterScopeVillain: Embla]].
700*** Book 2 starts off with a BigBadDuumvirate between Veronica and Surtr, king of Múspell, but [[spoiler:Surtr betrays her and becomes the sole main villain from that point forward. Veronica, for her part, has a HeelFaceTurn at the end of the book]].
701*** Book 3 focuses on Hel, ruler of the land of the dead.
702*** Book 4 focuses on Freyja, ruler of Dökkálfheimr, the realm of nightmares.
703*** Book 5 focuses on Fáfnir, the once-kind ruler of Niðavellir who has gone insane and now hungers for conquest. [[spoiler:He's just a brainwashed pawn, though; the true villain is the sorceress Eitri, who will go to any lengths to expand Niðavellir's power.]]
704*** Book 6 focuses on Embla, the GreaterScopeVillain of Book 1 and goddess of the Emblian Empire who wants to destroy the royal family of Askr [[spoiler:and was manipulating Veronica and Bruno in Book 1 to fulfill this goal]].
705*** Book 7 focuses on Gullveig, an extratemporal being who seeks to destroy the present. [[spoiler:It later turns out that King Njörðr of Vanaheimr was the one who orchestrated her creation in order to destroy humans to satisfy his own vanity, but Gullveig kills him shortly after this is revealed, holding on to the position of "main villain".]]
706** ''VideoGame/FireEmblemWarriors'' ostensibly has King Oskar of Gristonne who seeks to revive Velezark, the evil Chaos Dragon of legend. However [[spoiler:Oskar dies as TheUnfought, leaving a Velezark possessed Darios to take the role of BigBad]].
707** In ''VideoGame/FireEmblemWarriorsThreeHopes'', the main antagonist slot is occupied by [[CorruptChurch Rhea, Archbishop of the Church of Seiros]] and/or [[ANaziByAnyOtherName Thales, leader of "those who slither in the dark"]], with the specifics depending on route. [[TinTyrant Edelgard von Hresvelg, emperor of the Adrestian Empire]] is also a major antagonist on two routes, but she is always eclipsed by a greater threat somehow.
708*** On the Scarlet Blaze route, Rhea and Thales form a BigBadEnsemble and oppose you in equal measure. Edelgard, for her part, is TheHero of this route.
709*** On the Azure Gleam route, you initially face Edelgard, but [[spoiler:she is ambushed and brainwashed by Thales midway through the game, leaving him the clear-cut BigBad]]. Rhea, for her part, is a SupportingLeader and ally throughout the route.
710*** On the Golden Wildfire route, you initially face Edelgard, but [[spoiler:Claude eventually decides he likes the Church less and turns Leicester against them, leaving Rhea the clear-cut BigBad]]. Thales, for his part, falls off Claude's radar and never shows up in person.
711* ''Franchise/FiveNightsAtFreddys'':
712** The franchise-wide BigBad is William Afton, a child-murdering SerialKiller whose victims go on to haunt the animatronics and try to kill you. Anything from the franchise can be connected to him.
713** In ''VideoGame/FiveNightsAtFreddys1'', the titular Freddy Fazbear has this role, being the leader of the animatronics and your greatest threat.
714** In ''VideoGame/FiveNightsAtFreddys2'', the Puppet has this role, as she is the one who gave life to the murdered children, allowing them to possess the animatronics. However, later games repaint her as the ''BigGood''. A really misguided GoodIsNotNice BigGood, but one nevertheless.
715** In ''VideoGame/FiveNightsAtFreddys3'', we have Springtrap, who is William himself after suffering a brutal death [[AssholeVictim that he totally deserved]].
716** ''VideoGame/FiveNightsAtFreddys4'' has a BigBadEnsemble. The villain of the minigames [[BigBrotherBully the Brother]], who bullied the minigame protagonist [[spoiler:and accidentally killed him by stuffing him into Fredbear's mouth, giving us The Bite of '83]]. In the nights, Nightmare Fredbear will be your biggest threat.
717** ''VideoGame/FiveNightsAtFreddysSisterLocation'' has Circus Baby, who manipulates the protagonist, [[spoiler:Michael Afton]], up until night 5 where she, now a part of Ennard, reveals her true plan moments before [[spoiler:killing Michael. [[BackFromTheDead He gets better.]]]]
718** ''VideoGame/FreddyFazbearsPizzeriaSimulator'' has Springtrap, now known as simply Afton, and Baby, now known as Scrap Baby, who came to this location to murder children, and have the most focus out of every other animatronic. However, [[EvilerThanThou Afton is clearly superior]].
719** ''VideoGame/FiveNightsAtFreddysVRHelpWanted'' has the virus known best as Glitchtrap, William BackFromTheDead for the second time. He is the main reason for the creation of the tapes scattered across the game, and tries to [[spoiler:leave the game by possessing your body]].
720** ''VideoGame/FiveNightsAtFreddysSecurityBreach'' has Vanny, who hacked the animatronics and is hunting Gregory on [[GreaterScopeVillain Glitchtrap]]'s orders. The ''Ruin'' DLC has [[spoiler:the Mimic, a dangerous robot that impersonates Gregory to lure Cassie into freeing it]].
721* ''VideoGame/TheFlowerCollectors'': Haussmann is a CorruptPolitician who is not behind the murder of the Mole and the rampant political violence depicted, but he is also responsible for creating the eponymous Flower Collectors, a raid unit that went around suppressing any anti-nationist figures in Spain; the unit in question ended up killing no less than a dozen innocent people, and Haussmann has been spending his time as a politician to cover-up his past misdeeds.
722* ''VideoGame/ForHonor'': Apollyon, the warlord of the Blackstone Legion who finds the concept of peace so distasteful that she deliberately provokes the three factions to continue warring against each other.
723* ''VideoGame/ForestOfDrizzlingRain'': The Kotori Obake is a malicious {{Youkai}} who kidnaps children who step foot in her forest, and Shiori must rescue Sakuma from her and escape her to avoid becoming her next victim.
724* ''VideoGame/ForeverHome'': The rogue Tren general and main antagonist of the game, Barclyss, is determined to wipe out all life on the planet because he believes life is meaningless. To that end, he slaughters countless people to turn them into undead soldiers and later uses an orbital fortress, Affliction, to blast the planet's surface into oblivion. While he's not the leader of his country, he's the biggest threat in the story and even the actual leader of his country teams up with the heroes to stop him.
725* ''VideoGame/ForgottenWorlds'' has the Celestial Emperor Bios, a powerful being bent on taking over all life on the universe, one planet at a time.
726* ''VideoGame/{{Forspoken}}'': [[BigBadEnsemble The four Tantas]], the once-benevolent rulers of the realm turned wicked tyrants, are the biggest threat Frey must face on her journey, with Tanta Sila[[note]]The Tanta of Strength[[/note]] in particular being described as the most formidable of the four, and is the one most directly hunting Frey. [[spoiler:However, the true villain is Cuff, who turns out to be Susurrus, an ancient demon from Athia's past that wants to destroy the land, whom the four Tantas sealed inside themselves. [[GreaterScopeVillainThis eventually drove them insane]]. Once Frey kills the other three cuffed Tantas, Susurrus is able to reassemble himself and attempts to pull a YouHaveOutlivedYourUsefulness on Frey.]]
727* The Platform/DSiWare game entitled ''Foto Face: The Face Stealer Strikes'' has the professor as the antagonist, though the description of the game mentions the professor as the Face Stealer. The professor copies your face and then causes you pure hell by wrecking havoc, causing some to blame you, while some are working for the professor, and the remaining others don't know what the heck they are doing, attacking you for no reason. However, six of the characters are not evil. Anyway, you have to chase down the professor and fight him.
728* ''VideoGame/FragileDreamsFarewellRuinsOfTheMoon'' has Shin, a MadScientist who wants to bring about the end of the world using the Glass Cage [[spoiler:after its effects drove him to madness]].
729* ''VideoGame/FranBow'': Remor, a [[EmotionEater Kamala]] who murdered Fran's parents and spends the game hunting her down.
730* ''VideoGame/FreedomPlanet'' has Lord Brevon, an alien warlord who kickstarts the plot by turning the three kingdoms against each other so he can acquire the Kingdom Stone.
731** ''VideoGame/FreedomPlanet2'' has Merga, a water dragon freed from her prison after the events of the first game. She plans to resurrect Bakunawa so she can use it to devour Avalice's moon and reign supreme against the earth dragons.
732* ''VideoGame/FreedomWars'' has Abel "Strafe" Balt, who wreaks havoc with his own Abductor [[spoiler:for the goal of uniting all Panopticons by freeing the horrors that lurk in The Casket]].
733* ''VideoGame/{{Friendship}}'': [[spoiler:[[{{Yandere}} Kayako]], friend of Risa and Mio,]] is the one responsible for Mio's disappearance, [[spoiler:as she killed both her and her mom and is hiding Mio's body for herself; [[BigBadEnsemble meanwhile]], Mio's {{abusive|Parents}} mom haunts their house as a spirit]], and is the most direct danger to [[PlayerCharacter Risa]].
734* ''VideoGame/FroggersJourneyTheForgottenRelic'': The main antagonist is Eric von Viesel, an aristocrat who wishes to take OPART's power for himself and use it to create an ultimate weapon. [[spoiler: He's also responsible for the disappearances of Dr. Finnius, and later, Leona.]]
735* ''VideoGame/FrontMission'': Driscoll, the head of Nirvana Institute, which was to blame for most of the atrocities committed (namely [[spoiler:the BD Project, which involved using the brains of kidnapped soldiers as materials for biocomputers]]). He's also the greatest threat in the final mission, being the pilot of [[spoiler:the Mir Orlen unit]].
736[[/folder]]
737
738[[folder:G]]
739* In the first ''VideoGame/GalaxyAngel'' trilogy there's Gern, leader of the Valfasq. Exiled prince Eonia had no connection with them when he orchestrated his plot in the first game.
740** The SequelSeries ''VideoGame/GalaxyAngelII'' has the Will, who want to reset time altogether. Once again, the first game's plot mastermind (in this case Verel) has no connection with them.
741* In the ''VideoGame/GearsOfWar'' series, Queen Myrrah is the leader of the Locust Horde and the overall main antagonist of the original trilogy as a whole, with RAAM being TheDragon and TheHeavy in the first game, and Skorge being TheDragon and TheHeavy in the second. Myrrah herself takes center stage as the main antagonist in the third game.
742** The second trilogy starts off with "The Speaker", a leading member of the Swarm, TheRemnant and the evolved form of the Locusts, as the nominal [[TheHeavy main antagonist]] of the fourth game, and the Swarm Queen [[spoiler: Reyna Diaz, daughter of Myrrah]] emerges as the leader of the Swarm in the fifth game.
743* ''VideoGame/GeneTroopers'': [[spoiler:[[MadScientist Ithaka Wassali]], the true mind behind the Galactic Empire who brainwashed President Horacious Prowler into forming the Gene Troopers and spreading oppression across the galaxy]].
744* ''VideoGame/GetInTheCarLoser'': Jonivanjo the Machine Devil is an AncientEvil being that is fated to appear every millennium to kill everyone that its [[PoliticallyIncorrectVillain bigoted cultists]] hate. It grants cyborg powers to its cultists so they can break its seal before the 1000 year deadline.
745* ''VideoGame/{{Gex}}'' series has Rez, the cruel ruler of the Media Dimension who intends to ensure the world is subjected to nothing but bad TV shows and Z-grade movies.
746* ''VideoGame/GenshinImpact'' has a BigBadEnsemble between the Tsaritsa (the Cryo Archon and the mastermind behind the Fatui) and the [[spoiler:Traveler's Sibling]] (the leader of the Abyss Order). Overshadowing both of them, however, is the Unknown God in the intro who serves as the catalyst for the Traveler's journey to begin with and may in fact also be responsible for [[spoiler:[[BrainwashedAndCrazy corrupting]] the Sibling.]]
747%%* ''VideoGame/GhostsNGoblins'': Astaroth
748* ''VideoGame/GhostOfTsushima'': Khotun Khan, the leader of the Mongol Invaders that Jin must face. It's his desire to conquer the mainland of Japan that drives the conflict of the main story.
749* ''VideoGame/GhostReconWildlands'': [[LargeAndInCharge El Sueño]], the head of the Santa Blanca Cartel.
750* ''VideoGame/{{Ghostrunner}}'': [[EvilutionaryBiologist Mara/The Keymaster]] and [[spoiler:[[CyberneticsEatYourSoul Adam/The Architect]]]] are competing with each other for supreme control of the Tower, while also planning to exploit its citizens to their own ends
751* ''VideoGame/GhostTrick'' has a BigBadDuumvirate between Commander Sith, leader of a foreign espionage organization and [[spoiler: Yomiel]], the Manipulator seeking vengeance by [[spoiler: using his ghost powers to [[DemonicPossession manipulate]] and kill those he blames for ruining his life, as well as being the real man in red instead of Sissel]]. They've made a deal of mutual benefit to [[spoiler: wipe out all the people who knew of Temsik]], but each of them has a separate agenda, [[spoiler: and it ends with Sith double-crossing Yomiel]].
752* ''VideoGame/{{Ghostrunner}}'': Mara/The Keymaster and [[spoiler:Adam/The Architect]] are competing with each other for supreme control of the Tower, while also planning to exploit its citizens to their own ends.
753* ''VideoGame/{{Ghoulboy}}'' has The Goblin King, who allows monsters to roam the land of Gunzabar freely, and kidnapped [[PlayerCharacter Thulgar's]] dad in hopes of stopping a prophecy that would end in the king's downfall.
754* ''VideoGame/{{Gift|2001}}'': The Shadow of the Black Deep Dark Night. [[NonActionBigBad Despite being the BigBad, The Shadow shows to Gift once and never fights him directly]].
755* ''VideoGame/GnarledHag'': The titular [[WickedWitch Gnarled Hag]] has imprisoned the girl inside her house, and the girl must escape while hiding from her.
756* ''VideoGame/GodEater'':
757** ''VideoGame/GodEater1'' has [[spoiler:Johannes von Schicksal, who's advancing his own "Ark Project" designed to to save up to 1,000 handpicked individuals while causing the Devouring Apocalypse]].
758** ''VideoGame/GodEater2'' has [[spoiler:Rachel Claudius, who's out to cause the Devouring Apocalypse herself]].
759** ''VideoGame/GodEater3'' has [[spoiler:Abraham Gadolin [[BigBadEnsemble and]] [[AntagonisticOffspring his son Werner Gadolin]], who aim use all the AGEs, including children (and/or Phym) as fuel for Odin in an attempt to save humanity]].
760** ''VideoGame/CodeVein'', a SpiritualSuccessor and [[spoiler:StealthSequel]], has [[spoiler:Juzo Mido, the leading Revenant researcher who's responsible for the creation of the Successors]].
761* ''VideoGame/GodHand'' seemingly has Belze of the Four Devas, [[spoiler: but it turns out be Angra, the true cause of the demon outbreak]].
762* ''VideoGame/TheGodOfCrawlingEyes'': The titular [[EldritchAbomination God of Crawling Eyes]] is attacking the school, having been summoned by a cult, and Max must escape it.
763* ''VideoGame/GodOfWar'':
764** [[WarGod Ares]] in the [[VideoGame/GodOfWarI first game]] is leading an invasion on the city of Athens and only Kratos can stop him by finding Pandora's Box.
765** [[OmnicidalManiac Persephone]] in ''[[VideoGame/GodOfWarChainsOfOlympus Chains of Olympus]]'' plots to submerge the world in complete darkness just before destroying all of existence.
766** [[TheGrimReaper Thanatos]] in ''[[VideoGame/GodOfWarGhostOfSparta Ghost of Sparta]]'' is holding Kratos' brother Deimos in his domain and Kratos needs to find a way to free him.
767** [[DarkActionGirl Alecto]] in ''[[VideoGame/GodOfWarAscension Ascension]]'' is the leader of the Furies tormenting Kratos for breaking his oath to Ares and he must kill them to get rid of his bond.
768** [[EvilOverlord Zeus]] in the [[VideoGame/GodOfWarII second]] and [[VideoGame/GodOfWarIII third]] main installments, since he is the target of Kratos' revenge after he betrayed and tried to kill him.
769** [[ImplacableMan The Stranger]], [[spoiler:later revealed to be Baldur]] in the [[VideoGame/GodOfWarPS4 soft reboot]], hunting down Kratos and Atreus throughout the game. [[PlayingWithATrope Played with]] as the story focuses completely on Kratos and his son's journey and the Stranger comes across as a PlotIrrelevantVillain. [[spoiler:He is taking orders from [[GreaterScopeVillain Odin]] instead, as Odin promised to lift the curse placed upon Baldur in exchange for his service.]]
770** [[ControlFreak Odin]] in ''[[VideoGame/GodOfWarRagnarok Ragnarok]]'', hunting down Kratos and Atreus as part of his obsessive quest for knowledge and to avert Ragnarok.
771* ''VideoGame/GoldenAxe'': Death Adder, who takes the Golden Axe and ravages the land. [[spoiler:However, in the console version, [[PaletteSwap Death Bringer]] is the true BigBad and TheManBehindTheMan to Death Adder.]] In ''II'', the one who steals the Golden Axe is Dark Guld, and in ''III'', it's Damud Hellstrike.
772* Each ''VideoGame/GoldenSun'' game has a BigBadDuumvirate, who are fought as a DualBoss, and the series antagonist Alex:
773** The first game, ''[[VideoGame/GoldenSun1 The Broken Seal]]'', has the trio of [[LaughablyEvil Saturos]], [[LadyOfBlackMagic Menardi]], and Alex. The former two are Mars Adepts that lead the original effort to break the seal on Alchemy and bring it back to the world of Weyard, though Saturos is the dominant of the two. The latter is a former Mercury Clan member who betrayed the group and joined up with the other two because he shares their goals.
774** The second game, ''[[VideoGame/GoldenSunTheLostAge The Lost Age]]'', has Alex again, this time joined by the pair of Mars Adepts [[BareFistedMonk Agatio]] and [[LittleMissBadass Karst]], who seek to continue the work of Saturos and Menardi by lighting the four Elemental Lighthouses and restoring Alchemy to the world, and [[AvengingTheVillain avenge their deaths]] at the hands of Issac, though Agatio is the dominant one of the pair, and ItsPersonal for Karst, Menardi’s younger sister.
775** ''VideoGame/GoldenSunDarkDawn'' has [[CastingAShadow Blados]], [[TheVamp Chalis]], and [[TheChessmaster Arcanus]], who work for the [[TheEmpire military nation of Tuaparang]] and seek the Apollo Lens to bring about the Grave Eclipse. The former two are a pair of dark adepts, while the latter is a Mercury Adept whom any person who played the first games will instantly recognize as Alex. [[spoiler:It’s eventually revealed that Blados and Chalis [[TheStarscream plan to betray Tuaparang with the Apollo Lens]], while Alex betrays them in turn, seeking the Apollo Lens for himself.]]
776* ''VideoGame/GoodBoy'': [[spoiler:The Toy Box Demon]] is the grandmother's master who has her pressure the protagonist into murdering his family.
777* ''VideoGame/{{Gothic}}'': The Sleeper, a powerful demon who's the reason the barrier around the Colony got out of control.
778* The ''VideoGame/{{Gradius}}'' series:
779** [[TheEmperor Bacterion]] is usually the Big Bad of the majority of the games, being the master and creator of the entire Bacterian Empire that Gradius fights against.
780** Gradius II, IV, and Nemesis III (not to be confused with Gradius III) sees [[DragonAscendant Gofer]] lead the Bacterian forces against Gradius.
781** Nemesis II, Nemesis III, [[spoiler:Salamander for the MSX version, Gradius V, and Gradius Rebirth]] has [[WasOnceAMan Dr. Venom]], who's constantly tries to destroy Gradius as revenge for using his people.
782** Salamander/Life Force has [[DraconicAbomination Zelos]], a PlanetEater out to devour the Metalion solar system.
783** Salamander 2 has [[HumanoidAbomination Doom]], the leader of the Salamander force.
784** Gradius Gaiden has [[GiantSpaceFleaFromNowhere O.V.U.M]] (Original Visions of Ultimate Monster), the game's FinalBoss.
785* The ''VideoGame/GrandTheftAuto'' series:
786** ''VideoGame/GrandTheftAuto2'': The Zaibatsu Corporation, the {{Megacorp}} that controls most of the city.
787** ''VideoGame/GrandTheftAutoIII'': [[DarkActionGirl Catalina]]. She's behind the proliferation of SPANK, the new drug sweeping Liberty City, and betrayed Claude at the beginning of the game to join the Cartel, eventually becoming its de facto leader and having them shoot Claude on sight. She's also the most powerful mob boss of the entire game.
788** ''VideoGame/GrandTheftAutoViceCity'': [[TheDon Sonny Forelli]]. Over the course of the game, Sonny grows increasingly impatient and angry as Tommy builds his own empire instead of getting Sonny's money and drugs back. It gets to a point where he sics Mafia "taxmen" down to Vice City to take a cut of Tommy's business, and when that fails, shows up personally to kill Tommy. [[spoiler:And then it turns out he was behind the Harwood ambush that cost Tommy 15 years of his life.]]
789** ''VideoGame/GrandTheftAutoSanAndreas'': [[DirtyCop Frank Tenpenny]], who pulls the strings of nearly every major conflict in the game, and even when he isn't behind everything, he'll find some way to blackmail Carl into doing some dirty work for him; [[BigBadEnsemble and]] [[spoiler:[[BitchInSheepsClothing Big Smoke]], who betrays the Families to Tenpenny]].
790** ''VideoGame/GrandTheftAutoAdvance'': [[FauxAffablyEvil King Courtney]], the leader of the Yardies, and [[spoiler:[[UngratefulBastard Vinnie]], who tries to kill Mike after FakingTheDead]].
791** ''VideoGame/GrandTheftAutoLibertyCityStories'': [[TheChessmaster Massimo Torini]], having masterminded the MobWar between the three families and is directly or indirectly behind almost every conflict fought in the game.
792** ''VideoGame/GrandTheftAutoViceCityStories'': [[TheSociopath Jerry Martinez]], who Victor's out to kill as revenge for getting him discharged, and [[SiblingTeam the Mendez Brothers]], Vice City's biggest drug cartel.
793** ''VideoGame/GrandTheftAutoIV'': [[spoiler:[[OpportunisticBastard Dimitri Rascalov]]]], who is responsible for almost all the major conflicts in the game. If you choose the Revenge Ending, [[spoiler:[[SmugSnake Jimmy Pegorino]]]] becomes the BigBad and FinalBoss.
794** ''VideoGame/GrandTheftAutoIVTheLostAndDamned'': [[FalseFriend Billy Grey]], the president of the Lost MC's Alderney chapter who betrayed Johnny Klebitz.
795** ''VideoGame/GrandTheftAutoIVTheBalladOfGayTony'': Ray Bulgarin, who's out to kill Tony and Luis after they try to take his diamonds.
796** ''VideoGame/GrandTheftAutoChinatownWars'': [[spoiler:[[EvilUncle Wu "Kenny" Lee]], who orchestrated the death of Huang's father and has been manipulating Huang in a bid to replace Hsin Jaoming as head of the Liberty City Triads]].
797** ''VideoGame/GrandTheftAutoV'': [[MillionairePlayboy Devin Weston]] [[BigBadEnsemble and]] [[NotSoWellIntentionedExtremist Steve Haines]], both of whom blackmail the protagonists into committing crimes for them, with Devin having more direct influence.
798* ''VideoGame/{{Grandia}}''
799** [[VideoGame/Grandia1 First game]]: Gaia, a being born from a corrupted Spirit Stone responsible for destroying the Angelou civilization, and upon his reawakening, intends to do the same to the rest of the world out of disgust for humanity.
800** ''VideoGame/GrandiaII'': Pope Zera, the head of the Church of Granas who plots to summon the Dark God Valmar and use his power to destroy humanity.
801%%* ''VideoGame/GravityRush'' has [[spoiler: has The Darkness for the series as a whole]].
802* ''VideoGame/TheGreatGaias'': Grindelwald Maultor, [[spoiler:who is really the dark god Malviticus]], establishes the empire of Validus to wage war against the elves and claim the Hourgem of Valnyr, which he plans to use in order to rewrite history in his favor. After he's sealed in the Tower of Illyrium, his servants manipulate many nations to unseal him, resuming his plans to take over all of Tenat [[spoiler:and the Celestial Realm]].
803* ''VideoGame/GrimFandango'': [[TheDon Hector [=LeMans=]]], the crime Lord of El Marrow who's behind the corruption in the Department of Death. He has been stealing tickets from the deserving and selling them to richer, less saintly souls. Or so he'd have them believe, but the tickets he sells are fake. He keeps the real ones for himself, determined to hoard enough to balance out his numerous and horrific misdeeds in life.
804%%* In the ''{{VideoGame/Grow}}'' game series:
805%%** The red demon from ''Grow RPG''.
806%%** The purple creature from ''Grow Comeback''.
807* ''VideoGame/TheGuidedFateParadox'' has Satanael Kyogoku, who has felled entire parts of Celestia before the start of the story. The focus of the game is for Renya Kagurazaka to become strong enough to fight him.
808* All ''VideoGame/GuildWars'' campaigns have Big Bads of some sort, except perhaps Prophecies (which has several evil groups). The Nightfall campaign also [[spoiler:makes Abaddon the big bad of the first three campaigns]].
809* Lou the Devil in the ''VideoGame/GuitarHero'' series tries to get aspiring rock-stars to sign his contract so he would get possession of their souls, and also kidnaps the God of Rock in order to get an artifact to drain audiences of their souls.
810* ''VideoGame/GuiltyGear'' has That Man, who created the Gears, who in turn have wreaked havoc on the world. He's a pretty ambiguous guy (no one even knows his name) and not much is known about him or what he's planning. [[spoiler: It's subverted however, when he is revealed in ''Xrd -Sign-'' to have been GoodAllAlong, trying to stop the KillAllHumans plan of the real villain, Ariels.]]
811* ''VideoGame/{{GUN}}'': Colonel Thomas Magruder, [[FromCamouflageToCriminal a civil war vet turned criminal]] who leads the Texas Mountain Rifles and has taken large parts of the western territories both from the Apache tribes and Federal Government.
812* ''VideoGame/GunsGoreAndCannoli'': [[spoiler:Frankie the Fly is the one behind the zombie outbreak in Thugtown, having poisoned the local alcohol supply using a batch of special poison concocted by a German scientist he was in contact with. Following his plan getting foiled at the end of the first game, he returns as this in ''2'', under the alias of the Dark Don, [[PiggybackingOnHitler working closely with Hitler]] and ThoseWackyNazis in attempting to TakeOverTheWorld]].
813[[/folder]]
814
815[[folder:H]]
816* ''VideoGame/{{Hades}}'': While not a villain [[AntiVillain per say]], [[AntagonistTitle Hades]] himself acts as the main opposition in Zagreus' quest to escape the Underworld, with everyone who opposes Zagreus working under Hades' orders.
817* ''VideoGame/HakaiouKingOfCrusher'': While your unnamed protagonist isn't intentionally hostile, the game does have a main villain, in the form of the alien bug who injects you with a monstrous venom. Because said bug is a highly-manipulative alien creature who ''wants'' to destroy entire worlds, and it's using ''you'' as it's pawn. [[spoiler:The bug even ''screws you over'' in the final cutscene - by infecting your baby with another dose of it's venom, turning your child into another monster to start the cycle of destruction anew.]]
818* In ''VideoGame/HalfLife1'', and its expansion packs ''Decay'', ''Blue Shift'', and ''Opposing Force'', the Big Bad would have to be the Nihilanth, the creature that was maintaining the rift all along, while acting as the telepathic commander of the entire Xenian invasion force.
819** In ''VideoGame/HalfLife2'' and its Episodes, it's Wallace Breen, former administrator of Black Mesa and the human ruler of Earth under the Combine who commands LesCollaborateurs. [[spoiler:However, with Breen's death at the end of the game, the two episodic expansions have his superiors, the Combine Advisors, take full control with a vengeance. You focus on breaking the remnants of the Combine forces on Earth and keeping them from opening a portal back to one of their home dimensions.]]
820* ''Franchise/{{Halo}}'':
821** ''VideoGame/HaloCombatEvolved'' lacks a specific BigBad, though [[spoiler:343 Guilty Spark]] is featured as TheHeavy during the final act, and is directly behind one of the two massive threats to the galaxy.
822** ''VideoGame/Halo2'' and ''VideoGame/Halo3'' has the BigBadEnsemble of the Prophet of Truth, and the Gravemind. Truth due to being the leader of the Covenant and primary instigator of the Human-Covenant War and Gravemind for being the {{Hivemind}} of [[TheVirus the Flood]]. Truth is also this for ''VideoGame/Halo3ODST'', though he only physically appears in the [[HarderThanHard Legendary]] ending.
823** ''VideoGame/{{Halo 4}}'' introduces a new Big Bad in the form of [[spoiler:the Didact, the former military leader of the Forerunners]]. Also, Jul 'Mdama, leader of the Covenant remnant, is this for the ''Spartan Ops'' co-op campaign.
824** ''VideoGame/Halo5Guardians'' has [[spoiler: Cortana]], who's had a FaceHeelTurn offscreen in between games.
825** ''VideoGame/HaloInfinite'' has [[spoiler:the Harbinger, a mysterious entity allied with Escharum's Banished and helping them to repair the Zeta Halo. It's revealed towards the end that she's a representative of a [[GreaterScopeVillain much more dangerous force]], [[TheGhost the Endless]]]].
826** The closest thing ''VideoGame/HaloReach'' has to a BigBad is the unnamed Elite Field Marshal who seems to be leading most of the Covenant ground troops that the player personally fights (specifically, those of the Fleet of Valiant Prudence).
827** ''VideoGame/HaloWars'' has Arbiter [[DragonInChief Ripa 'Moramee]]. While subordinate to the Prophet of Regret, Ripa is a much more authoritative and physical threat.
828** ''VideoGame/HaloWars2'' has [[GeniusBruiser Atriox]], leader of the Banished, a Covenant splinter-faction.
829* ''VideoGame/HandInHand'': [[MyNameIsQuestionMarks ???]], the shadowy figure chasing the two heroines around in Momoyama Academy, is one of the spirits of the three kokeshi dolls, who kill anyone who removes the dolls from the shrine the heroines happened to be there when the dolls were stolen. [[spoiler:Or so it seems, but it turns out to actually be a bank robber who got himself trapped in the school, though there are [[MaybeMagicMaybeMundane hints]] that the spirits may have been involved after all.]]
830* ''VideoGame/HarmoKnight'': [[HumanoidAbomination Gargan]] is the leader of the [[AliensAreBastards Noizoids]] who intends to [[TakeOverTheWorld become ruler of all of Melodia]] and fill it with endless noise.
831* ''VideoGame/AHatInTime'' is divided into chapters each with their own set of {{Arc Villain}}s to deal with like [[TheMafia the Mafia Boss]] in Mafia Town and [[DealWithTheDevil The Snatcher]] in Subcon Forest, but the real BigBad of the game is [[spoiler:Mustache Girl, a WellIntentionedExtremist who is so overzealous about ridding the world of bad guys that she's willing to steal all of Hat Kid's Time Pieces and alter the entire world under her rule. However, she is not very prominent until the final chapter of the game and is mostly out-of-focus for the remaining chapters, with only vague hints that she influenced some of the plot from behind the scenes]].
832* ''VideoGame/TheHauntedMansion'': Atticus Thorn, an EvilSorcerer who seeks to use the power of the six soul gems to destroy both the afterlife and the living world.
833* ''VideoGame/HauntingGround'': [[spoiler:[[MadScientist Lorenzo]] is behind virtually everything bad that happens to Fiona throughout the entire game. Every stalker after her is his creation and has their sights on Fiona because of the Azoth in her body.]]
834* ''VideoGame/HavenCallOfTheKing'': Lord Vetch, the evil GalacticConqueror out to kill Haven and prevent him from summoning [[BigGood Athelion]].
835* ''VideoGame/HeavenlySword'': [[spoiler:The Raven Lord, the spirit of a warlord who corrupted Bohan into villainy to get ahold of the Sword]].
836* ''VideoGame/HeavyRain'' has [[SerialKiller the Origami Killer]] [[spoiler:a.k.a. [[DirtyCop Scott Shelby]]]], who targets Ethan's son as his next victim and who Madison and Norman spend the game tracking down.
837* ''VideoGame/TheHeilwaldLoophole'': [[MadDoctor Joseph Randolf]], the chief doctor of the titular hospital who uses the power of the Ominous Voice to turn it into a nightmarish hellscape where no one is allowed to die.
838* ''VideoGame/HelloHello'': The ghost of [[spoiler:Akari]] haunts the room where Kazuki is staying and tries to kill him [[spoiler:so she can [[{{Yandere}} be with him again]], while the ghost of Kazuki in the AlternateUniverse does the same thing to the alternate Akari]].
839* ''VideoGame/HelloPuppets'': [[PerversePuppet Mortimer]], the star of Mortimer's Handemen and the mastermind of the puppets who plots to dominate the world and make all humans into hosts.
840* ''VideoGame/HenryStickminSeries'':
841** ''Infiltrating the Airship'' has the [[EvilBrit Toppat Clan Leader]], the leader of a gang of high-class criminals. To gain a pardon, [[BoxedCrook Henry Stickmin]] has to take down the Clan.
842** ''Fleeing the Complex'': Dimitri Johannes Petrov is the warden of the Wall, a maximum-security prison that Henry is trying to escape from.
843** ''Completing the Mission'': The Toppat Clan returns as the main villain of the game as it centered around them building a rocket in a secret jungle base in order to launch the remaining Toppat members to the space station which renders them untouchable by the government and depending on the paths Henry took in the previous game, will either find a way to sabotage them or ensure they launch successfully. However, who the leader of the clan is dependent on the route taken in ''Airship''. If ''Rapidly Promoted Executive'' or ''Pure Blooded Thief'' ending are chosen, then Reginald remains as the leader. In ''Ruthless Bounty Hunter'' where Reginald has been arrested, then the Right Hand Man becomes the leader while in ''Government Supported Private Investigator'' where both are arrested, Sven Svensson becomes the new leader of the surviving Toppat members.
844* ''VideoGame/HeroKingQuestPeacemakerPrologue'': The Hero King of the Cerulean Land plans on invading the Dark Realm and slaughtering all the Dark Ones. The party has only four days to organize the realm in order to defeat the Cerulean army.
845* ''VideoGame/HeroesMustDie'': [[NamesToRunAwayFromReallyFast Lord Murder]], the evil overlord that the hero is forced to work it.
846* ''VideoGame/HexyzForce'': [[TheEmperor Emperor Axel]] of [[TheEmpire Rosenbaum]], once a beloved leader until [[LoveMakesYouEvil the assassination of his wife]], [[EvilOverlord now seeks to conquer the world]]. [[spoiler:[[DiscOneFinalBoss However]], he’s a BrainwashedAndCrazy pawn of [[TheManInFrontOfTheMan Faust]] [[TheArchmage Schnizer]]; he, [[EnfantTerrible Azul]]/[[TwoBeingsOneBody Galiza]], [[GodIsEvil Norvia]], and [[SatanicArchetype Delgaia]] [[BigBadEnsemble are all competing for control]] over the Hour of Judgement, and whoever comes out on top depends on the ending.]]
847* ''VideoGame/{{Hitman}}'':
848** ''[[VideoGame/HitmanCodename47 Codename 47]]'' has Otto Wolfgang Ort-Meyer, the MadScientist who created 47.
849** ''[[VideoGame/Hitman2SilentAssassin Silent Assassin]]'' has Sergei Zavorotko, leader of TheMafiya.
850** ''[[VideoGame/HitmanContracts Contracts]]'' has Inspector Fournier, as the one who managed to put 47 in the jeopardy that constitutes the game's FramingDevice.
851** ''[[VideoGame/HitmanBloodMoney Blood Money]]'' has Alexander Leland Cayne, the leader of the Franchise.
852** ''[[Videogame/HitmanAbsolution Absolution]]'' had a BigBadEnsemble with [[FatSweatySouthernerInAWhiteSuit Blake Dexter]] and [[GeneralFailure Benjamin Travis]] as the central antagonists who both want 47 and the child he's protecting dead.
853** ''VideoGame/{{Hitman|2016}}'' doesn't have a central villain, instead dealing with the ICA being caught in a proxy war between [[TheIlluminati Providence]] and [[MysteriousBacker the Shadow Client]], with the Shadow Client being the more prominent antagonist while Providence largely remains [[GreaterScopeVillain in the background]].
854** ''VideoGame/Hitman2'' continues the story of the conflict between Providence, [[MouthOfSauron represented]] by [[TheDragon the Constant]], and the Shadow Client, who is now seen as a WellIntentionedExtremist opposing Providence.
855** ''VideoGame/Hitman3'' concludes the fight against Providence, with the Shadow Client/Lucas Grey [[spoiler: who is 47's childhood friend Subject 6]] as an ally to 47, while the Constant, Arthur Edwards [[spoiler:[[TheStarscream has betrayed]] his superiors, the Partners, who lead Providence. The Partners are relegated to DiscOneFinalBoss status, and the Constant takes over as the leader of Providence and therefore is the unambiguous main villain]].
856* ''VideoGame/HollowKnight'': [[spoiler:[[MothMenace The Radiance]], a god-like entity responsible for the plague that destroyed Hallownest]].
857* ''VideoGame/{{Homefront}}'': Jim Jong Un, the leader of the Greater Korean Republic out to take over the United States.
858* ''VideoGame/{{Homeworld}}'':
859** The [[TheEmperor Taiidan emperor]] from ''Homeworld''. Spends most of the game in the shadows, but according to the [[AllThereInTheManual backstory]] for ''Homeworld: Cataclysm'', he was a twisted, ruthless mess of a ruler who managed to stay on his throne by cloning himself, and who ordered the destruction of a planet [[spoiler:-- namely YOURS --]] mostly as a publicity stunt.
860** [[TheVirus The Beast infection]] is the primary antagonist in ''Homeworld: Cataclysm'', and towards the end of the game it is controlled by [[spoiler:The [[HiveMind Nagarrok]], an ancient alien vessel that picked up the Beast infection in Hyperspace]]. It even has its own [[TheDragon Dragon]] in the [[spoiler:infected lower half of the Somtaaw Command Ship]].
861** [[GalacticConqueror The nomadic Vaygr]] from ''Homeworld 2'' are led by [[DarkMessiah Makaan]] in their attempts to conquer the galaxy. Unusually for a BigBad, he's [[spoiler:killed before the end of the game, and you spend the last mission fighting off what's left of his fleet as they try to bomb your planet]].
862** [[VisionaryVillain The K'Had Sajuuk]], leader of the [[WellIntentionedExtremist Kiith Gaalsien]], in ''Homeworld: Deserts of Kharak'', who seeks to stop the Kharaki space program and destroy the Coalition to bring peace to and protect Kharak.
863* ''VideoGame/HopkinsFBI'': Bernie Berckson, a SerialKiller [[PlayerCharacter J. Hopkins]] spends the game pursuing after he kidnapped his girlfriend.
864* ''VideoGame/{{Horace}}'': [[spoiler:The [[BrainMonster Ether Boss]]]] is the leader of the robots in the Old Man's estate and the greatest obstacle to Horace's mission to end the RobotWar, [[spoiler:[[DiscOneFinalBoss until]] his defeat. Then it becomes a BigBadEnsemble between the robot leaders/advisors and the [[CorruptPolitician Man in Black]], the seemingly nice leader of "[[GovernmentConspiracy The Great and the Good]]" who created the robots and wants to [[FinalSolution kill them all]]]].
865* ''Horizon'' video game series:
866** ''VideoGame/HorizonZeroDawn'': HADES. Formerly a subroutine of [[BigGood GAIA]], along with the rest of the subroutines unshackled by a "[[GreaterScopeVillain mysterious signal]] (turning out to be [[spoiler:Nemesis]])", HADES becomes a highly independent AI of a chaotic nature, whose job is to eradicate life on Earth, reflecting his native purpose to reverse GAIA's terraforming, should it fail. It serves as the [[spoiler:true leader of the Eclipse]].
867** ''Horizon Zero Dawn: The Frozen Wilds'': The Daemon is responsible for augmenting many of the machines, known as the Daemonic Machines, around the Cut, who all pose as an existential threat to the Banuk tribals. [[spoiler:Turns out that the identity of the Daemon is HEPHAESTUS, a rogue subroutine of GAIA, who is the mastermind of weaponising all of GAIA's machines, as well as imprisoning CYAN inside Cauldron EPSILON.]]
868** ''VideoGame/HorizonForbiddenWest'': While [[BaldOfEvil Gerard Bieri]] is seen to be the immediate threat to Aloy and her team, as well as the tribal inhabitants of Zero Dawn Earth, [[spoiler:Tilda van der Meer is revealed to be the true BigBad of the game]]. She is [[spoiler:a member of Far Zenith and Elisabet Sobeck's former love interest, who became profoundly grieved with her death]]. After [[spoiler:she finds Aloy, however, her companionship later grows obsession over her, which culminates into her defection to Far Zenith and joins with Aloy's team to put an end to Bieri's plans of stealing GAIA and terraforming another planet to his image while leaving Earth to Nemesis]]. But this is eventually revealed to be a blatant lie at the end, as she [[spoiler:betrays Aloy and her team after finding out the truth behind Nemesis and her plans to kidnap Aloy and leave Earth to the insane AI, making her the FinalBoss of the game]].
869* ''VideoGame/HouseOfTheDead'' series: Caleb Goldman causes most of the zombie outbreaks either directly or [[TheManBehindTheMan from behind the scenes]]. However, [[spoiler:there is an [[GreaterScopeVillain even bigger mastermind above him]], and it's the Mysterious Man]].
870%%* ''VideoGame/{{Hydlide}}'' series: Varalys, the final boss of the original. He's [[DemotedToDragon reduced to the Dragon]] in Hydlide II and Super, with a dark crystal and Kaizack of Big Bad of the respective games.
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