I agree with the "Must set up another trilogy" aspect, the final chase scene ended spectacularly enough but I was hoping for something a bit more resolute to the story, otherwise it just sort of ends and leaves things wide open. Overall the only real issue I have with it is that there is not quite enough plot to justify the running time, both the Alaska scenes and the final chase were a little long winded. 115 minutes would have been just about perfect instead of 135 minutes.
Renner matches the physicality that Damon brought to the series and I might add he makes Aaron Cross more sympathetic than another actor might have taken the role. Cross is actually very selfish throughout the film (constantly begging people for his chems), but he does it with a layer of desperation and otherwise good heart that keeps him from being too one-note.
I did enjoy the look into the background process of Treadstone, Blackbriar and examining how much support those programs had to have in order to function. It confirmed the hints in the original about them being more than just Charles Atlas Superpower
but being actually chemically enhanced Super Soldiers
. And Norton's comment "We aren't going to touch Bourne, we're here in case things go the way we think they are going" was a good hint to the audience on what to expect.