Base Breaker: The excruciating detail the movie goes into showing the war crimes. While such horrific acts did indeed happen, some have argued that, like films such as The Passion of the Christ, the film focuses too much on them, and not enough on the actual victims or perpetrator's reasons for doing so, making the whole thing come across as exploitative rather than informative.
Fridge Horror: Well, not so much fridge, but when one remembers that this was based on a true story...
Nausea Fuel: The pressure chamber scene. Frankly, if a man's intestines squirting out of his anus doesn't warrant Brain Bleach, it's hard to conceive of what does.
Nightmare Fuel: Many of the experiments seemed to have no purpose other than creative abuse of the human body.
Signature Scene: The part where a cat gets eaten alive by a horde of rats seems to be the movie's most infamous scene, mainly because it caused debates over whether or not the sequence was real.