These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
YMMV: GURPS
Game Breaker: For the most part, GURPS seems content to leave the game breakers in, but charge out the nose for them.
Specifically Cursed means the GM gets to do anything he wants to your character for any reason at any time.
Destiny is a bit more complex. GM abuse stems from the notion that you don't control how your Destiny (positive or negative) is fulfilled, the GM does. Exact Words can bite you bad if you try to become invincible by taking a seemingly impossible Destiny that involves your death.