The Europansare the inusannon They're decended from refugees from the cycle before the Protheans and are referred to as the 'precursors of the precursors'. The race that filled the 'precursor' role for the Protheans are the inusannon, about whom nothing is know beyond their tech and a couple of battles that they fought. Them being the same race would also explain why the author chose to name the Europans after where they live rather then giving them a proper species name; it's probably going to come up at some point in the future and he wants to have it as a plot twist.
The Berserkers were created as anti-Reaper Training from HellGiven that the timeline is techinally set in the Mass Effect universe, that means that the Reapers are out there. Given what the Berserkers are and their MO it's not too hard to see them being made by a long-dead race with the intention of 'toughening up' the Local Cluster races so that they'd have a fighting chance against the Reapers.
The number of spacefaring races in the Local Cluster isn't naturalAs has been mentioned on the main page the number and variety of spacefaring races in the Local Cluster exceeds that of the rest of the Mass Effect galaxy. If this was natural it'd be somewhat implausible,however if someone had been going around playing uplifter then it'd make a good deal more sense. It's even mentioned in-story that a precursor race (the 'Tharks') noted that the number of sapient species in the area was unusually high and suspected outside interference of some sort.
The entire Local Cluster is part of extinct race's plan to get revenge from beyond the graveCarrying on from the above two ideas, maybe the same race that created the Berserkers did something to ensure the development of as many space faring races as possible in order to better play the numbers with the above mentioned Training from Hell with the intention of producing at least one species, or alliance of species, that was advanced enough and tough enough to beat the Reapers, sort of an interstellar version of The Spartan Way.
When they finally meet, the Local Cluster races are going to be weirded out by the Council racesSpecifically by the fact that so many of them are humanoid. After all, when it comes to sapient species in the Local Cluster, no two body plans occur twice, with even the other bipedial species having enough non-human characteristics to keep them out of the Humanoid Alien catagory. The Council species on the other hand are almost all humanoid which would most likely seem strange and possibly suspicious to the Local Cluster races. Or, to paraphrase a comment on the Spacebattles thread, once is convergent evolution, half a dozen times is suspicious, and the asari are a sign that there's something wrong with the universe.
Anonymous will end up leading/guiding/otherwise influencing the gethWhen the Local Cluster meets the Council races, it is only a matter of time until the internet comes into contact with the extranet and when that happens it is inevitable that a certain AI will find their way into the latter. Since the geth are stated to monitor the extranet, it is equally inevitable that said AI will run into them sooner or later. And given that getting involved with the geth has considerable potential for simultainously doing good and trolling the organics, Anonymous will almost certainly take an interest. Especially since Word Of God implies that Nony may be literally living up to the 'We are legion' part of their namesake's motto.
First Contact with the Council races will literally be with the Citadel itselfWord Of God is that contact will take place in the 2080s. O'Neil is heading in the right direction and as of the most recent (as of 16th November) instalment they've spotted what is probably the Serpent Nebula, added it to their 'sight seeing' list and will get there sometime in the 2080s. Given that O'Neil is an FTL-capable mini-Citadel with a large number of armed escorts, if this guess is correct then things are going to be interesting.
The Migrant Fleet are not the only, or indeed even the largest, remaining Quarian faction.Based primarily on the author remarking that he always suspected that some Quarians chose to embrace the newly-sapient Geth as their equals, fought alongside them when others tried to destroy them, and were spared exile as a result. There's odd hints of this in the text as well, such as the wiki entry on the Geth specifying that "a part" of the Quarian population was forced off-world.
We haven't heard the last of Skynet.With or without his unfortunate Omnicidal Maniac tendencies. The fact that the Council races and their enemies have taken to using for-real Terminators doesn't bode well either. And come to think of it...
The relative legal status of AIs is going to create considerable friction when it becomes widely known in Compact space.Council-space AIs being a Slave Race not wholly unlike the Jem'hadar is not likely to go over well with Compact AIs, an ethnic group that can all vote and include several individuals of no mean power and influence.
The Berserkers are a Training Program from Hell... and an effort of this universe's Cerberus...Think about it.
The Compact's closest/friendliest allies outside the Local Bubble will be the Unified AssemblyAfter some initial tenseness the two seem to have hit it off when diplomatic contact was first established, it was the first time someone had made contact, and friendly contact at that, with the Assembly (aka the geth and Rannoch-born quarians) in a hundred and eighty years (they were very interested to hear news of what had been going on in the wider galaxy while they were isolated), and at the moment they're the only two polities where AIs and organics are equals and have a fully intergrated society.