Trivia: NYPD Blue
- Actor-Shared Background: Dennis Franz, like Sipowicz, is/was a Vietnam veteran.
- Cast the Expert: Consultant and former New York detective Bill Clark was seen a few times as a cop.
- Dueling Shows: with Homicide Life On The Street
- Moral Guardians: The show was frequently rapped for its language and nudity, but rarely for the much more frequently occuring violence.
- Real-Life Relative: Lola Glaudini played the squad's secretary, Dolores Mayo. Glaudini's father, Robert Glaudini, played Dolores's father, Jimmy Mayo.
- You Look Familiar:
- Richard Gant appears a few times as the desk sergeant at another precinct, then later as a municipal bus driver who witnesses a perp running away from the scene of a crime.
- Charlotte Ross appeared in a couple of episodes in season five as a cop's battered wife before returning in season eight as Connie McDowell.
- Silas Weir Mitchell as an abusive boyfriend in one episode, and later as a crime scene witness.