- Acclaimed Flop: Despite very good reviews from critics, the film raked in only $12.5 million out of a $36 million budget.
- Deleted Scene:
- The head janitor gives Vincent some fatherly advice when he first works at NASA and is later shown to be his Secret-Keeper, with the two having a joking conversation before the final mission.
- The geneticist describes the process more, reveals that all babies are made heterosexual, and nonchalantly talks about disposing of the leftover embryos once the Freemans' pick the one they want.
- Detective Hugo reveals to Anton that he's figured out he and the In-Valid fugitive are brothers, but he doesn't rat them out.
- Romance on the Set: Ethan Hawke and Uma Thurman got married two years after meeting in this film and had two children (including Maya Hawke) but they have since separated.
- What Could Have Been: John Cusack, Johnny Depp and Sean Penn were offered the role of Jerome/Eugene Morrow.
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