Drusilla is in Hollywood with her real accent but Spike is nowhere to be seen.
Playing Against Type: An oddly specific example in Maurice LaMarche, who dubbed over the physical performance of Vincent D'Onofrio as Orson Welles. Throughout his career, LaMarche has lampooned Welles dozens, if not hundreds, of times, but in Ed Wood he plays him entirely straight for the first (and perhaps only) time.
Real-Life Relative: Averted. Martin Landau stars and his daughter Juliet plays Loretta King, but the two aren't related in-universe/
What Could Have Been: An earlier version of the screenplay featured Wood's ultimately doomed marriage to Norma McCarty, which was depicted as ending the minute she found out he was a cross-dresser. (In reality, McCarty didn't exactly approve of his cross-dressing, but was willing to put up with it for the sake of their relationship. What really killed their marriage was Wood's alcoholism and abusive behavior towards her son from her previous marriage)