Life Imitates Art: Just as this film (based on actual events) was released, US missions in Libya, Egypt and Sudan were attacked. Perhaps the greatest coincidence? The head of the US Embassy in Sudan, Joseph Stafford, was one of the house guests portrayed in the film. An interview with Stafford can be found here.
Reality Subtext: "You can teach a Rhesus monkey to be a director in two days." This line is spoken to Ben Affleck, himself the director of this movie.