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Tear Jerker: Neverwinter Nights
The section of the original campaign in Charwood gradually becomes one as the PC discovers what happened there.
In Hordes, the Sleeping Man's True Love is randomly determined. If it turns out to be the Sensei, get the tissues ready. The Sensei has devoted her entire life to worship of the Sleeping Man and truly is in love with him. When you awake him and tell the two of them that she is the True Love he's been waiting for, she panics, not ready for a closer relationship , and teleports away to parts unknown leaving him to follow.