This is based on opinion. Please don't list it on a work's trope example list.
Tear Jerker / Hotel Dusk: Room 215
Plenty of them, though some think the worst is Dunning being unable to even look up as he quotes the last thing Bradley said to him. "You won't see Robert Evans again." To those of you reading this who haven't played the game, this will mean nothing. To those who have, you'll understand the circumstances. The music helps as well.
You missed his big line. Five words: "I just want my Jenny...".
And if you got the best ending: ..."Jenny?"
When Melissa first explains what happened to her Mum.
When Louie talked about what happened to him and Danny.