Episodes from Season 5 are themed around mashing together the titles of one good and one bad movie, among them "No Country for Old Dogs".
In a sketch from "The Curious Case of the Box", which parodies Dora the Explorer, Boots is tempted to tell Dora that her hair looks like Javier Bardem's from this movie.
In "Waverly Hills 9-0-2-1-D'oh", the Inspector is a parody of Anton Chigurh, right down to the "friend-o" catchphrase.
In "White Christmas Blues", Bart plays a video game called Frosty the Hitman, in which he destroys a stand of ridiculous Christmas DVDs, including one for No Country for Fat Old Men, whose cover depicts Santa Claus with a shotgun.
South Park: In "Band in China", the scene of Randy murdering Winnie the Pooh parodies the scene where Chigurh kills the deputy with his handcuffs.