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Zig Zagged: While a number of the foes that the heroes fight are the offspring of Ich'goa, many others are simply allied with Ich'Goa.
Averted: Everything evolved separately as it normally does.
Enforced: "How can I ensure that the heros have an endless supply of monsters to fight without just handwaving the problem, and still have all of them be unique...?"
Lampshaded: "Shub-Niggurath called; she says you'll be hearing from her lawyer."
Invoked: A race of Sufficiently Advanced Aliens want to make monsters to fight their enemies; instead of cloning a thousand creatures, they create just one mother.
Exploited: The heroes realize that the only way to end this once and for all is to take out Ich'Goa herself.
Defied: Ich'Goa creates numerous slightly less fertile and creative daughters and makes efforts to ensure genetic diversity and fertile breeding in their offspring, so that she is only indirectly the source of all monsters.
Discussed: “Wait, so Ich’Goa gave birth to ALL of the fiendish beasts we fight?... Wow. She Really Gets Around…”
Deconstructed: All the monster races birthed by Ich'Goa are related to each other by genetics, and cannot breed without resulting in incestuous, deformed children. As a result, when Ich’Goa dies, entire species start to degenerate to the point of extinction.
Played For Laughs: Ich’Goa is constantly nagging the monsters she spawned, asking them to clean their lairs, demanding tribute on mother’s day, asking them why they never write and making them wear jumpers when she's cold...
Ich'Goa is not evil, and has no control over her offspring and whether she has them. The offspring are not Always Chaotic Evil, and in fact are just as often friendly Starfish Aliens as ravening monstrosities. Before she was enslaved by the Evil Overlord she worked with her good offspring to protect the world from her more dangerous children. The heroes are shocked by this revelation, and must decide if killing her is really necessary.