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- In GI Joe: A Real American Hero #26, the Soft Master disassembles the handgun of a young hoodlum trying to hold up his store, ejecting the ammunition cartridge and the round in the chamber.
- Played for laughs in You Don't Mess with the Zohan, where the lead character takes apart a goon's assault rifle ridiculously fast.
- In Lethal Weapon 4, Jet Li's character escapes a Mexican Standoff this way.
- In Five Card Stud, some gold miners are concerned that there's a killer loose and the marshal can't or won't do anything about it, so they march towards the marshal's office, one of them carrying a shotgun, intent on taking the law into their own hands. One of the marshal's deputies accosts them, takes the shotgun, and empties it of shells.
- Parodied in Wayne's World when Garth grabs Russell's flashlight out of his hand and immediately opens it and removes the batteries.
- In The Bourne Identity, Jason Bourne disarms two French police officers and ends up holding one of their sidearms. He dismantles it in about half a second and runs away.
- In The Dark Knight, when the Joker's men attack Bruce's penthouse, he disables an unsuspecting mook and immediately disassembles his shotgun whilst making speed to intercept Harvey and get him to safety. Like most horizontal break-opens, this one indeed can be taken apart by pulling a single lever. The film's prop master likely chose that model of shotgun for its ease of disassembly.
- In Rush Hour, when Detective Lee comes to the consulate and beats up the FBI agents guarding the front door, he takes one of their guns and disassembles it, apologizes, and finds another way in.
- Ip Man manages to do this to Inspector Li's service revolver, somehow popping out the cylinder in spite of the thick metal pin keeping it attached to the gun.
- In Short Circuit, a villain pulls a gun on the Johnny 5, who takes it out of his hand and destroys it.
Johnny 5: Colt .45. Semi-automatic.[crushes the gun]Johnny 5: Play-doh.
- In Sherlock Holmes: A Game of Shadows, a mook attempts to shoot Holmes with a revolver at point-blank range. Holmes grabs the revolver out of the mook's hand, empties the chamber of bullets with one motion, and then hands the gun back to the mook.
- Watchmen has Laurie AKA Silk Spectre snatch a Beretta 92F off her government handler and take it apart in less than a second. The Beretta is typically used for such scenes, because you can push the magazine release with one hand (the magazine will drop free) and simultaneously use the other hand to turn the very convenient disassembly lever and take the slide off forward - all in one easy fluid motion. Ejecting the round in the chamber is not necessary.
- Kingsman: The Secret Service incorporates the "Beretta disassembly" (Beretta 92F pistols are extremely convenient to take down in one motion) into the church scene - with the hero then proceeding to stab people with both the slide and the frame. Repeatedly.
- In Mad Max: Fury Road, Max manages to slam the magazine release on Furiosa's pistol and clear the chamber right before she's about to blow his brains out, causing them to scramble for the magazine.
- In Feet of Clay, Dorfl does this when he goes to the slaughterhouse for payback after being given free will and someone attacks him with a hammer.
- In Harry Potter and the Philosopher's Stone, when Hagrid is banging on the door of the shack in which the Dursleys are trying to hide from the Hogwarts letters, Vernon comes downstairs with a shotgun. After Hagrid breaks down the door, Vernon threatens him with it, and Hagrid yanks the gun out of his hands, ties the barrel in a knot, and tosses it in the corner.
- Artemis Fowl: Julia removes an important part of a mook's gun as he brandishes it, making it only possibly useful as a hammer.
- On The Adventures of Superman after the villain got done Shooting Superman, Superman would often grab the barrel and twist it into a curve so it's unusable.
- In Better Call Saul, "Pimento", when Mike is hired as a bodyguard for a drug deal, his fellow bodyguard is a Gun Nut who thinks Mike will be useless on the job because he didn't bring a gun. Mike says "If I need one, I'll take one of yours", and the Gun Nut dares him to try, pointing a gun right in his face. Mike easily takes the gun away from his attacker and ejects the magazine and the bullet in the chamber. He then uses the empty gun to hit the other guy in the throat which takes him out of the fight completely.
- Eliot Spencer from Leverage can do this and does it on a regular basis. Justified because he's one of the world's best fighters and he Doesn't Like Guns.
- In Lost, Kate does it with instruction from Sayid in the second episode, right after Sawyer shoots the polar bear. Later we learn she didn't necessarily need it.
- In Star Trek: The Original Series, Khan grabs Kirk's phaser out of his hands and bends it in half.
- In the Vengeance Unlimited episode against a rogue IRS agent, during the final confrontation Mr. Chapel snatches his gun and empties it.
- Daredevil: Matt has a tendency to dismantle guns mid-combat to keep his enemies from using them.
- In Batman: Arkham City and Batman: Arkham Origins, Batman can learn the Disarm and Destroy special combo move, which allows him to destroy weapons during combat. When he uses it against henchmen armed with firearms, he pulls the weapon apart before dropping the pieces. Henchmen can pick up and reassemble their guns, so keep your ears open for the Dramatic Gun Cock.
- In Batman: Arkham City they can pick up but not reassemble. (If the gun was dropped when Batman knocked someone down or out, a henchman can pick it up, but Disarm and Destroy prevents them from doing so.)
- In Metal Gear Solid 3, The Boss does this to Snake at least twice in cutscenes, destroying his sidearms in the process. She does it to Ocelot once, but then gives him back the parts she removed rather than throwing them away. She also uses it as a tactic in the final fight if she manages to knock you onto the ground while you're holding a weapon. For gameplay reasons, this just means The Boss will scatter your intact weapon and its ammo around the battlefield, forcing you to scramble and retrieve them; it's also an incentive to use CQC on her rather than trying to shoot her.