A very sweet touching scene comes in Season 8, at the funeral of Chuck Vance. Bree tells Renee that she will always be her closest friend, even if she's known the other girls longer, simply because she was there to save her life.
Doubling with Tear Jerker is Mary Alice's ending narration for "Bang!" Normally, she acts as a detattached omnicisent narrator. In this instance, she says that this would be the last time Lynette would dream of her, and that she is glad for it, a rare gesture of emotion on Mary Alice's part.