The story takes place about six months after the Rapture. As Rayford Steele, his daughter Chloe, and reporter Buck Williams are searching for answers behind the vanishings, a power broker named Jonathan Stonagal is planning to take over the world during a time of crisis by setting up a one-world economy, using the Romanian president Nicolae Carpathia as his puppet leader.
This film provides examples of:
- Adaptational Nationality: Dirk Burton, who was British in the book series, is American in this film.
- Adaptation Name Change: Amanda White, who is a character who appears in the second book, becomes Amanda Wright in this film.
- The Antichrist: As the title says, the Antichrist emerges to set up the coming one-world government. Some believers think it is Jonathan Stonagal, but it turns out to be Nicolae Carpathia.
- As the Good Book Says...: Scripture verses are used throughout the movie to explain the situation in the story.
- Brainwashing: Nicolae Carpathia gets all those present at the United Nations security council meeting except for Buck (and this time his friend Connor) to believe that the murders of Jonathan Stonagal and Joshua Todd-Cothran were actually killed by the security guards in defense of Nicolae.
- Comic-Book Time: An unfortunate case being that, despite Left Behind (2014) taking place in The New '10s and this movie taking place in The New '20s, no more than six months have passed between the events of the two movies.
- Defacement Insult: Rayford sees a pig's head with a crown of thorns put upon the cross of an abandoned church, no doubt done by vandals as an insult to God and Jesus Christ. There's also GOD IS DEAD written on the walls inside the church.
- Dies Differently in Adaptation: In the book series, Dirk Burton is killed by a gun shot that was made to look like a suicide. In this film, Dirk Burton dies by a car bomb explosion, a fate that happened in the book to British investigator Alan Thompkins.
- Does This Remind You of Anything?: The Antichrist's program for controlling the networks is entitled "Dominator", an obvious parallel to the real-life Dominion Voting Systems.
- Garbage Hideout: Buck Williams hides himself inside the dumpster with the computer he's trying to protect from a couple of hitmen who are trying to find and kill him. The hitmen fire into the dumpster to make sure he's dead. Buck survives, but the computer gets a bullet lodged inside its case and is rendered useless.
- Gender Flip: Investigative reporter Eric Miller from the first book becomes Erica Miller in this film.
- Global Currency: Jonathan Stonagal wants the world to accept Eden Pay as a one-world form of currency. Bruce Barnes equates this to being the forthcoming Mark of the Beast, as prophesied in Scripture.
- Hide the Evidence: Dirk Burton has a laptop computer that has all the evidence of Jonathan Stonagal's connections hidden behind a vent casing, which Buck later goes into to rescue the computer from hitmen.
- Judgment Of The Dead: Chloe dreams of standing before Jesus and handing Him a photo of herself, awaiting judgment. Jesus looks at her, shakes His head no, and prevents her from going through the door to meet with her brother Raymie.
- Not Even Bothering with the Accent: The actor playing Romanian president Nicolae Carpathia speaks with an American accent.
- Oh, Crap!: The moment when Buck Williams realizes from hearing his friend Chaim Rosenzweig mention a seven-year agreement with Israel and the United Nations that it ties in with the Biblical prophecy of a coming prince who will "confirm a covenant with many for one seven," that the signing of the treaty with Israel would start the seven-year Tribulation.
- Pop-Up Texting: This occurs when Rayford Steele is looking up the Rapture on his phone, and when Dirk Burton is trying to hack into the Eden website through his computer.
- Race Lift: Pastor Bruce Barnes, a white man in the books, is African American in the films. This one is no exception.
- String Theory: Conspiracy theorist and informant Dirk Burton has a board like this in his office that connects every news and media outlet that he knows about to Jonathan Stonagal, including the news network that Buck Williams has worked for.
- Video Will: Pastor Vernon Billings leaves behind a DVD explaining what's happened, which Rayford Steele and Bruce Barnes watch together in the abandoned church, which leads both of them into accepting Jesus Christ as their Lord and Savior.
