Adam
- Body Horror: His body is covered in stitches as expected from an being composed of multiple body parts.
- Disappeared Dad: Adam is driven to resurrect his creator, who died shortly after bringing him to life.
- Frankenstein's Monster: The one and only, albeit looking closer to his book counterpart than the Boris Karloff's depiction.
- Younger Than They Look: His official age is listed as one year old, despite looking like an fully grown adult.
Arctorious
Caleb
Dr. Hyde
Erzsebet Bathory
- Ax-Crazy
Gabriel
- Expy: To Donovan Baine from Darkstalkers since he is another Hunter of Monsters that risks becoming a monster himself.
- The Hero: He is designed to be the main protagonist.
- Hunter of Monsters: He was recruited and trained by Zafkiel specifically for the task.
- You Killed My Father: His mother was murdered in front of his eyes by monsters, which lead him down his path of hunting them.
Imhotep
Quasimodo
- Adaptational Badass: While Quasimodo was very strong in his own right in the source material, here he is made into an cyborg and is capable of throwing down with creatures like werewolves, vampires, flesh golems and etc. Quasimodo is also biologically immortal.
- Cyborg: His left arm was replaced by a mechanical prosthetic.
- Handicapped Badass: He is still a hunchback and lost his left arm, which he had replaced with an prosthesis in order to fight.
- The Lost Lenore: He was in love with Esmeralda just like in the book, but she was hanged for witchcraft due to safeguarding the Book of Tears.
Radegonda
- Succubi and Incubi: She became a succubus through means of dark magic.
- That Man Is Dead: Adheleid is no more, all that is left is Radegonda.
Thalessa
Vladislav III
- Church Militant: As the heir to the Order of the Dragon, his own father was desperate to save him from his debilitating disease so that someone could become Christendom's sword and shield.
- Classical Movie Vampire: To be expected of Dracula.
- Dracula: The one and only, even if he is not referred to by this name.
- Historical Domain Character: He actually is Vlad the Impaler.
Zafkiel
- Action Girl: An powerful angelic warrior.
- Angelic Beauty: Though she looks just like an normal human, she is pretty gorgeous at that.
- Big Good: She is the most prominent heroic figure that is active in combating evil in the story. Zafkiel is also responsible for taking The Hero under her wing.
- Blade Below the Shoulder: Capable of emitting light blades from her arms.
- Expy: As the resident blonde Action Girl that uses kicks and back flicks, she is inspired by Sonya Blade or Nina Williams.
- Fallen Angel: She had lost contact with Heaven due to devoting her efforts in hunting down monsters.
