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* ''{{ComicBook/Bulleteer}}'': Lance tested his Smartskin on a mouse before he tried it for himself. The mouse survived and went on to become Alix's pet Mickey while Lance suffocated to death.
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* ''WesternAnimation/OneHundredAndOneDalmatiansTheSeries'': In the episode "Food For Thought", Rolly is kidnapped by P.H. Devil and locked in his lab in which he is fed an experimental food additive to test for any negative side effects. In the lab, Rolly meets several other animals who have also been tested on and deformed in one way or another. The testing is clearly portrayed as a bad thing, and in the end all the animals escape and P.H. Devil suffers the [[HoistByHisOwnPetard ill effects of his own experimentation]].
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* ''Literature/TheFold'' plays this trope both ways and comes out in the middle. The first experiment in teleportation is on the team's dog mascot: it goes gruesomely wrong and everyone on the team admits it was a terrible mistake. After the technology progresses they try again with hundreds of mice, a few cats, and a chimpanzee: while many of the mice are dissected to check for physical effects, the remainder of the test subjects are released to animal sanctuaries to live out their natural lives. The technology in question is of such world-shifting importance that the sacrifice of the dissected mice is justified.
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[[folder:Radio]]
* ''Radio/OurMissBrooks'': In "New Girl In Town", Miss Brooks and Mr. Boynton mention with sympathy several mice that have died in biology lab experiments. Mr. Boynton and Miss Brooks bury them at the side of the football field. Harriet Conklin uses this information to help scare off the titular new girl and her mother, by misrepresenting the mice as old girlfriends of Mr. Boynton.
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* ''VideoGame/{{Whiplash}}''.You play as two animals attempting to escape a lab.Note the sheer ridiculousness of the experiments being performed

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* ''VideoGame/{{Whiplash}}''.''VideoGame/{{Whiplash}}'': You play as two animals attempting to escape a lab.lab. Note the sheer ridiculousness of the experiments being performedperformed.

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* ''Franchise/WonderWoman'': A Golden Age story touched on this, with Gerta von Gunther experimenting on sharks, but then everything quickly shifts away from a more grounded example since she turns the sharks into winged mermaids with human level intelligence somehow and when they break out of their tanks to get revenge on her for keeping them in tanks and experimenting on them they're the ones treated as the villains.

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* ''Franchise/WonderWoman'': ''Franchise/WonderWoman'':
**
A Golden Age story touched on this, with Gerta von Gunther experimenting on sharks, but then everything quickly shifts away from a more grounded example since she turns the sharks into winged mermaids with human level intelligence somehow and when they break out of their tanks to get revenge on her for keeping them in tanks and experimenting on them they're the ones treated as the villains. villains.
** [[ComicBook/WonderWoman1942 Volume 1]]: Considering that Prof. Zool's "evolution" machine seems to turn whatever is placed in it into an approximation of an existing animal, with a few remaining traits of whatever it was originally it's definitely a good thing he doesn't use human subjects to experiment on. It's also not great that he uses animals since he has created one of Wonder Woman's most enduring supervillains using it, but the story makes the animal testing seem reasonable.
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* In ''Film/AntMan'', CorruptCorporateExecutive Darren Cross tests his reproduction of Pym particles on lambs. Hope thought they were going to use mice, Cross doesn't see what the big difference is. FridgeLogic kicks in when you consider how much cheaper mice are to raise and store... maybe he needed a bigger subject so when it got shrunk down it'd be easier to see?

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* In ''Film/AntMan'', ''Film/AntMan1'', CorruptCorporateExecutive Darren Cross tests his reproduction of Pym particles on lambs. Hope thought they were going to use mice, Cross doesn't see what the big difference is. FridgeLogic kicks in when you consider how much cheaper mice are to raise and store... maybe he needed a bigger subject so when it got shrunk down it'd be easier to see?
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* Touched on in an episode of ''Series/{{Castle}},'' wherein a cosmetic company executive is found dead with "Murderer" (well, "Murderc") written on his mirror. His assistant points the team to an animal right's group who's been protesting the company after the discovery that one of their affiliates used animal testing, though she does point out that the company itself has never used animal testing and cut its ties with the "guilty" organization upon discovery. The animal right's group is quickly eliminated as suspects and never appears onscreen, and no judgement is passed either way on the animal testing; it's simply identified as controversial.
** That said, it ''is'' a factor in the murder: [[spoiler:The negative publicity that came with the animal testing revelation led to a hit in the company's stock. When another product was found to be controversial, some of the company's employees decided to murder the exec rather than let him go public with a new scandal, which they feared would tank the company.]]
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* ''Literature/WordOfMouse'': [[TheProtagonist Isaiah]] and his family live in cages in an animal testing lab, and all they want to do is escape.

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* ''Literature/WordOfMouse'': [[TheProtagonist Isaiah]] Isaiah and his family live in cages in an animal testing lab, and all they want to do is escape.
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* ''{{Series/Probe}}'''s "[[Recap/ProbeMetamorphicAnthropoidicPrototypeOverYou Metamorphic Anthropoidic Prototype Over You]]": Dr Deanna Hardwick has been testing a new method of increasing intelligence on an orangutan. The result is a [[SuperIntelligence highly intelligent]] ape that sends Austin into a fury as he realizes just how badly Josephine had been abused to advance Dr Hardwick's position in the scientific community.
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* ''Literature/WordOfMouse'': [[TheProtagonist Isaiah]] and his family live in cages in an animal testing lab, and all they want to do is escape.
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->'''Co-Worker''': I suppose you'd rather we tested the lipsticks on people. Would you like your wife's lips to be like that poor moggy's mouth in there?

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->'''Co-Worker''': ->'''"Nasty"''': I suppose you'd rather we tested the lipsticks on people. Would you like your wife's lips to be like that poor moggy's mouth in there?
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->'''Gerry''': These cats in there are being smothered with lipstick just so that cosmetic firms can make money out of silly woman.
->'''Co-Worker''': I suppose you'd rather we tested the lipsticks on people. Would you like your wife's lips to be like that poor moggy's mouth in there?
->'''Gerry''': I don't want anyone's mouth to become like that: not my wife's, nor the cat's. There is no need to ''have'' lipstick, if it can only be got with suffering like this. Now if we were testing the animals for medical research, to help us cure terrible diseases, or something of that kind, I would understand it. But we aren't. That row of cages is lipstick. Over there, it is meant to be psychology, but we know perfectly well, we are just playing games with these animals. Look at those rats, smoking in there.
-->-- ''Literature/{{Stray}}''
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* ''VideoGame/LostInVivo'' has an entire level based around the horrors of animal testing. The experiments done in Nezumi Labs have no reasonable motive, producing horrific, impossible, morbidly fascinating but ultimately useless scientific “breakthroughs”. It gets so bad that [[spoiler: the combined pain eventually gives birth to the EldritchAbomination Sotiris]]
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* ''Franchise/SonicTheHedgehog'': ''VideoGame/SonicAdventure2'' shows that Eggman's father, Doctor Gerald Robotnik, was a scientist who tested on animals, anthropomorphic or otherwise. Shadow the Hedgehog is an [[ArtificialHuman Artificial Hedgehog]] created to help his terminally ill granddaughter, as well as society as a whole.

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* ''Franchise/SonicTheHedgehog'': ''VideoGame/SonicAdventure2'' shows that Eggman's father, grandfather, Doctor Gerald Robotnik, was a scientist who tested on animals, anthropomorphic [[FunnyAnimal anthropomorphic]] or otherwise. Shadow the Hedgehog is an [[ArtificialHuman Artificial Hedgehog]] created to help his terminally ill granddaughter, granddaughter Maria, as well as society as a whole.
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[[folder:Theatre]]
* In Noah Smith's stage version of ''Theatre/TheStrangeCaseOfDrJekyllAndMrHyde'', Jekyll tested the early versions of his formula on rabbits before he achieved a formulation promising enough to try himself. It's only mentioned as a passing detail, and there isn't any judging of animal testing per se; there's a description of "dead and deformed rabbits", but less as an argument against testing the formula on animals than as a suggestion that Jekyll is unwise to be trying to create the formula at all.
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* In ''Literature/SurvivorDogs'', a group of dogs evacuate into the local wilderness after earthquakes hit their city. The main humans they meet are people testing the environment. The dogs don't trust them and their trust is a good thing: the humans capture animals, keep them in cages, and force them to drink tainted river water. The humans are presented as jerks who laugh at [[spoiler:Fiery]] being caught in their net. They later get drunk on "fire-juice", as the dogs call it, and seem unprofessional.

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* In ''Literature/SurvivorDogs'', a group of dogs evacuate into the local wilderness after earthquakes hit their city. The main humans they meet are people testing the environment. The dogs don't trust them and their trust is a good thing: the humans capture animals, keep them in cages, and force them to drink tainted river water.water to see if it's safe or not. The humans are presented as jerks who laugh at [[spoiler:Fiery]] being caught in their net. They later get drunk on "fire-juice", as the dogs call it, and seem unprofessional.


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* ''Franchise/SonicTheHedgehog'': ''VideoGame/SonicAdventure2'' shows that Eggman's father, Doctor Gerald Robotnik, was a scientist who tested on animals, anthropomorphic or otherwise. Shadow the Hedgehog is an [[ArtificialHuman Artificial Hedgehog]] created to help his terminally ill granddaughter, as well as society as a whole.
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* In ''Literature/TheMigaxCycle'', the seserance is tested on rats at first, who foreshadow the fate of the human characters.
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[[folder:Music]]
* Music/CattleDecapitation have a song, "Clandestine Ways (Krokodil Rot)", whose lyrics describe an AnimalWrongsGroup that breaks into an animal testing lab, frees all the test subjects, then subjects the scientists to gruesome experiments similar to those they were performing, some involving the drug Krokodil (which can cause [[BodyHorror severe damage to the skin]]). Since this is a band that often presents their morals in an {{Anvilicious}} way, we're presumably meant to agree with the eco-terrorists, though not the exact methods they used.
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Cleanup of Sugar Wiki links on objective pages


* Discussed and parodied in ''VideoGame/NightTrap'': In the second part of the bathroom, Megan criticizes Lisa for trying to prime herself with her makeup, telling her that scientists should use cosmetic testing with her makeup on rats "before they let people like [her] play with it". Megan then demonstrates by pretending her hand is a rat facing torture by cosmetic testing, all the while using her squeaky mouse voice, as a way to mock Lisa. [[SugarWiki/FunnyMoments It's pretty hilarious.]]

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* Discussed and parodied in ''VideoGame/NightTrap'': In the second part of the bathroom, Megan criticizes Lisa for trying to prime herself with her makeup, telling her that scientists should use cosmetic testing with her makeup on rats "before they let people like [her] play with it". Megan then demonstrates by pretending her hand is a rat facing torture by cosmetic testing, all the while using her squeaky mouse voice, as a way to mock Lisa. [[SugarWiki/FunnyMoments It's pretty hilarious.]]
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* ''VideoGame/FireEmblemRadiantDawn' has Izuka's experiments turning laguz into rabid warriors, though made worse (and blurring the line of this trope) by the fact that laguz are [[FantasticRacism a race of people]] who can transform into animals.

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* ''VideoGame/FireEmblemRadiantDawn' ''VideoGame/FireEmblemRadiantDawn'' has Izuka's experiments turning laguz into rabid warriors, though made worse (and blurring the line of this trope) by the fact that laguz are [[FantasticRacism a race of people]] who can transform into animals.
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Corrected disambiguation link.


* The ''VideoGame/FireEmblemTellius'' games have Izuka's experiments turning laguz into rabid warriors, though made worse (and blurring the line of this trope) by the fact that laguz are [[FantasticRacism a race of people]] who can transform into animals.

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* The ''VideoGame/FireEmblemTellius'' games have ''VideoGame/FireEmblemRadiantDawn' has Izuka's experiments turning laguz into rabid warriors, though made worse (and blurring the line of this trope) by the fact that laguz are [[FantasticRacism a race of people]] who can transform into animals.

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See also AnimalWrongsGroup and ScienceIsBad for in-universe negative connotations towards this. See TestedOnHumans for the ''much maligned'' [[TakeAThirdOption third option]].

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See also AnimalWrongsGroup AnimalWrongsGroup, ScienceIsBad, and ScienceIsBad BadPeopleAbuseAnimals for in-universe negative connotations towards this. See TestedOnHumans for the ''much maligned'' [[TakeAThirdOption third option]].



* ''Film/IAmLegend'' with Will Smith featured large scale animal testing on rats. The experiments are for the sake of humanity, so it's good. The fact that they were ''infected vampiric'' rats probably helps justify his work, too.

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* ''Film/IAmLegend'' ''Film/IAmLegend'':
** ''I Am Legend''
with Will Smith featured large scale animal testing on rats. The experiments are for the sake of humanity, so it's good. The fact that they were ''infected vampiric'' rats probably helps justify his work, too.



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[[folder:Films -- Animation]]
* ''WesternAnimation/{{Felidae}}'', based on the book of the same name. Dear Lord. Like the murders weren't horrible fuel enough. Francis comes across a tape of a perfectly healthy cat, shown meowing and struggling, [[StrappedToAnOperatingTable being bolted to a table]] and having its head cut open to test a new "glue" for wounds. Said glue ''eats through its skull into its brain while it is conscious'' as the scientist impartially narrates and observes its dying twitches. Enough to give anyone nightmares (and check that your own pets are where you left them). As if that wasn't enough, most of the cats in Francis' neighborhood are mangled by the lab's experiments - Felicity is blinded, Bluebeard has a withered paw, and Claudandus goes insane.
* ''WesternAnimation/TheSecretOfNimh'': The animation in the laboratory, and the effects of the concoction given to the rats and mice, are pretty nightmarish. Notably, the injections to which the animals are subjected are of a ''much'' larger volume than could ever be given to such rodents without killing them in RealLife, suggesting that the lab-flashbacks are subjective memory, not objective fact. Weirdly enough, everything good about the rats is owed to these experiments.
* ''WesternAnimation/FernGullyTheLastRainforest'' doesn't just pack in enviromental issues - it shoves in the anti-animal-testing ones too, with the brutally-treated Batty Koda entering the "Batty Rap" which actually had some of the gorier imagery cut from it. Examples used in the song were mostly cosmetic, but the plot-affecting device was the radio antennae implanted in his head which sent him insane.
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* ''Stray'', a book by A.N. Wilson. Pufftail is captured and sent to a laboratory, used to test shampoo. That's unpleasant enough, but his record of a cat screaming "My eyes! I cannot close my eyes!" because [[EyeScream his eyelids had been cut off]] to test the effects of sleeplessness was horrifying.
* On that note... quite a few animal care books will warn you against thieves who kidnap pets in order to sell them to laboratories. Given that even people who support animal testing in principle would baulk at the idea of that happening to Tiddles or Fido... ParanoiaFuel, anyone? It is difficult to get a fix on the reality of this situation - pet care manuals and sites, and certainly the Animal Rights supporters, will definitely warn you against it; scientific sources will maintain it's an urban myth. What ''is'' true is that ''[[http://en.wikipedia.org/wiki/Laboratory_animal_sources animal shelters]]'' in certain US states are ''obliged'' to hand over animals to any "Class B" dealer (selling to laboratories) who asks for them.
** Happens sometimes in the present, and happened often in the past, but not entirely realistic--the vast majority of lab animals are bred in the labs, so that their genetics and upbringing are fully known. Using animals with unknown histories is a great way to mess up your research.

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* ''Stray'', ''Literature/{{Stray}}'', a book by A.N. Wilson. Pufftail is captured and sent to a laboratory, used to test shampoo. That's unpleasant enough, but his record of a cat screaming "My eyes! I cannot close my eyes!" because [[EyeScream his eyelids had been cut off]] to test the effects of sleeplessness was horrifying.
* On that note... quite a few animal care books will warn you against thieves who kidnap pets in order to sell them to laboratories. Given that even people who support animal testing in principle would baulk at the idea of that happening to Tiddles or Fido... ParanoiaFuel, anyone? It is difficult to get a fix on the reality of this situation - pet care manuals and sites, and certainly the Animal Rights supporters, will definitely warn you against it; scientific sources will maintain it's an urban myth. What ''is'' true is that ''[[http://en.wikipedia.org/wiki/Laboratory_animal_sources animal shelters]]'' in certain US states are ''obliged'' to hand over animals to any "Class B" dealer (selling to laboratories) who asks for them.
**
them. Happens sometimes in the present, and happened often in the past, but not entirely realistic--the vast majority of lab animals are bred in the labs, so that their genetics and upbringing are fully known. Using animals with unknown histories is a great way to mess up your research.



* In ''Literature/SurvivorDogs'', a group of dogs evacuate into the local wilderness after earthquakes hit their city. The main humans they meet are people testing the environment. The dogs don't trust them and their trust is a good thing: the humans capture animals, keep them in cages, and force them to drink tainted river water. The humans are presented as jerks who laugh at [[spoiler:Fiery]] being caught in their net. They later get drunk on "fire-juice", as the dogs call it, and seem unprofessional.



* ''WesternAnimation/{{Felidae}}'', based on the book of the same name. Dear Lord. Like the murders weren't horrible fuel enough. Francis comes across a tape of a perfectly healthy cat, shown meowing and struggling, [[StrappedToAnOperatingTable being bolted to a table]] and having its head cut open to test a new "glue" for wounds. Said glue ''eats through its skull into its brain while it is conscious'' as the scientist impartially narrates and observes its dying twitches. Enough to give anyone nightmares (and check that your own pets are where you left them). As if that wasn't enough, most of the cats in Francis' neighborhood are mangled by the lab's experiments - Felicity is blinded, Bluebeard has a withered paw, and Claudandus goes insane.
* ''WesternAnimation/TheSecretOfNimh'': The animation in the laboratory, and the effects of the concoction given to the rats and mice, are pretty nightmarish. Notably, the injections to which the animals are subjected are of a ''much'' larger volume than could ever be given to such rodents without killing them in RealLife, suggesting that the lab-flashbacks are subjective memory, not objective fact.
** Weirdly enough, everything good about the rats is owed to these experiments.



* ''WesternAnimation/FernGullyTheLastRainforest'' doesn't just pack in enviromental issues - it shoves in the anti-animal-testing ones too, with the brutally-treated Batty Koda entering the "Batty Rap" which actually had some of the gorier imagery cut from it. Examples used in the song were mostly cosmetic, but the plot-affecting device was the radio antennae implanted in his head which sent him insane.
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[[folder: Live-Action TV]]
* A sort-of SpaceWhaleAesop example appears in ''Series/StrangerThings''; we see flashbacks of the GovernmentConspiracy testing Eleven's psychic abilities, and -- just to reiterate that these aren't very nice people we're talking about here -- one of the tests involves trying to force Eleven (who, it should be noted, is a twelve-year-old girl) to use said abilities to murder an adorable little cat. When she (understandably) refuses, they try and shove her into a PunishmentBox -- at which point she uses her abilities to kill the orderlies doing so. The lesson, we guess, is to not force psychic preteen girls to try and murder kittens.
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* ''Franchise/WonderWoman'': A Golden Age story touched on this, with Gerta von Gunther experimenting on sharks, but then everything quickly shifts away from a more grounded example since she turns the sharks into winged mermaids with human level intelligence somehow and when they break out of their tanks to get revenge on her for keeping them in tanks and experimenting on them they're the ones treated as the villains.
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* ''Anime/PetShopOfHorrors'' throws a huge surprise the readers' way when it turns out that Count D -- who would seem to be the first person that would start lecturing a scientist -- is actually fairly laid-back on the animal testing issue.

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* ''Anime/PetShopOfHorrors'' ''Manga/PetShopOfHorrors'' throws a huge surprise the readers' way when it turns out that Count D -- who would seem to be the first person that would start lecturing a scientist -- is actually fairly laid-back on the animal testing issue.
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* Lisa in TheSimpsons is for animal rights. One episode involved her and Homer being framed for releasing a bunch of experimental animals by a private investigator, which included pigs slathered with makeup and monkeys addicted to cigarettes. Weirdly enough, in an earlier episode, Lisa had to do a science project, and conducted an experiment called ''is my brother dumber than a hamster?'', which involved a hamster being forced to undergo some very psychologically damaging experiments.

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* ''WesternAnimation/TheSimpsons'': Lisa in TheSimpsons is for animal rights. One episode involved her and Homer being framed for releasing a bunch of experimental animals by a private investigator, which included pigs slathered with makeup and monkeys addicted to cigarettes. Weirdly enough, in an earlier episode, Lisa had to do a science project, and conducted an experiment called ''is my brother dumber than a hamster?'', which involved a hamster being forced to undergo some very psychologically damaging experiments.
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* In ''Literature/AStudyInScarlet'', Sherlock Holmes tests what he believes to be poison by feeding it to a dog. [[spoiler:He's right, and the dog dies]]. However, it's pointed out in detail that the dog is very old, is suffering, is nearly about to die of natural causes anyway, and the landlady had asked Watson yesterday to put it out of its misery.

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* In ''Literature/AStudyInScarlet'', Sherlock Holmes tests what he believes to be poison by feeding it to a dog. [[spoiler:He's right, and the dog dies]]. However, it's pointed out in detail that the dog is very old, is suffering, is nearly about to die of natural causes anyway, and the landlady had asked Watson yesterday to put it out of its misery. So despite giving Holmes the scientific test he wanted, it's more of a MercyKill.
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* Sidney Harris, a science-themed panel cartoonist, once drew two scientists looking at a guinea pig almost completely hidden by a hat, with one saying "I thought they only tested ''drugs'' on guinea pigs."

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