History MadScientist / Comics

* A heroic Mad Scientist in The DCU is Doctor Magnus, creator of the MetalMen.

* Everett Ducklair, the creator of [[ArtificialIntelligence One]] and many of the gadgets [[PaperinikNewAdventures Paperinik]] uses, is a unwilling case: because of his ScienceRelatedMemeticDisorder, he simply can't create something without turning it in a weapon. He eventually retreats to a monastery to meditate and search for the better part of himself.

* {{ComicBook/Spider-Man}}'s ArchEnemy, DoctorOctopus.

** He did return to being a MadScientist in PostCrisis after the ''Up, Up, and Away!'' storyline, where Clark Kent brings his VillainWithGoodPublicity status down through journalism.

* Krona (of ''ComicBook/JLAAvengers'' fame) is a mad scientist from a species of humanoids who had discovered immortality and realized the potential of the mind's raw power well before Earth's solar system had formed. He was determined to unlock the secret of existence: How had the universe come into being? To this end, he created a "time window" that would allow him to peer at the moment of creation. Unfortunately, apparently the act of looking caused the creation to go awry, and instead of a single universe, a multiverse was formed. Unfortunately, this included one evil antimatter universe... and the seeds for the CrisisOnInfiniteEarths were sown. Krona was banished, but eventually was employed by Nekron (the Lord of the Unliving) and turned into the embodiment of entropy. As such, he gradually grew in power, until he reached a point where he ''vivisected entire universes'' in his restless quest for answers. He forcibly interrogated Galactus to find out what he knew. All in the name of ''science''.

** The original version of the character was actually a benevolent man who was ruined by being rejected by the scientific community [[TheyCalledMeMad for his ideas]]. When his wife died, he blamed the world and turned into the crackpot we love to hate. This was the PreCrisis origin, the current version seems to always have been mean.

* [[Comicbook/TheMultiversity Earth 44's]] Doc Tornado (a combination of the Metal Men's Doc Magnus and Red Tornado) is another heroic Mad Scientist.

* SelfDemonstrating/DoctorDoom.

* Krona (of {{JLA-Avengers}} fame) is a mad scientist from a species of humanoids who had discovered immortality and realized the potential of the mind's raw power well before Earth's solar system had formed. He was determined to unlock the secret of existence: How had the universe come into being? To this end, he created a "time window" that would allow him to peer at the moment of creation. Unfortunately, apparently the act of looking caused the creation to go awry, and instead of a single universe, a multiverse was formed. Unfortunately, this included one evil antimatter universe... and the seeds for the CrisisOnInfiniteEarths were sown. Krona was banished, but eventually was employed by Nekron (the Lord of the Unliving) and turned into the embodiment of entropy. As such, he gradually grew in power, until he reached a point where he ''vivisected entire universes'' in his restless quest for answers. He forcibly interrogated Galactus to find out what he knew. All in the name of ''science''.

* Doctor Sivana and his family are similarly the archenemies of [[Comicbook/{{Shazam}} Captain Marvel]] and friends. He's a five-foot-tall gnome of a man with a chrome dome, huge ScaryShinyGlasses, and more often than not a white lab coat. His stated goals (in no particular order): To become Rightful Ruler of the Universe in fact as well as in name; to spread evil, cruelty, and nastiness throughout the cosmos; and to humiliate, discredit, and ultimately ''KILL CAPTAIN MARVEL!'' Heh heh heh heh!!! What, exactly, his [[UglyGuyHotWife incredibly attractive and affectionate]] late wife saw in him is a total enigma.

* The Ultra-Humanite (arguably comics' first supervillain) who actually transferred his brain from the standard baldie-in-a-labcoat mad scientist's body into that of a beautiful woman. He was only another Mad Scientist in the [[TheGoldenAgeOfComicBooks Golden Age]] comics, but in the series ''Comicbook/TheGoldenAge'', he becomes the arch villain, [[spoiler:[[VillainWithGoodPublicity posing as a hero and getting the medal of honor]]. He saved Hitler's brain, too. And put it in an invincible super-body]].

* Samantha Argus of ''SafeHavens'' is a personable, enthusiastic grad student who has unlocked the genetic code. She has the power to transform practically any living creature.

* The Military Doctor in ''{{Sturmtruppen}}'': He believes he's discovered the Invisibility Elixir without getting insane, while his attendants point out that's actually the other way around. He also thought that a case of anemia was actually caused by a Vampire.

* Doctor Sivana and his family are similarly the archenemies of [[{{Shazam}} Captain Marvel]] and friends. He's a five-foot-tall gnome of a man with a chrome dome, huge ScaryShinyGlasses, and more often than not a white lab coat. His stated goals (in no particular order): To become Rightful Ruler of the Universe in fact as well as in name; to spread evil, cruelty, and nastiness throughout the cosmos; and to humiliate, discredit, and ultimately ''KILL CAPTAIN MARVEL!'' Heh heh heh heh!!! What, exactly, his [[UglyGuyHotWife incredibly attractive and affectionate]] late wife saw in him is a total enigma.

** In ''[[ComicBook/TheMultiversity Thunderworld #1]]'', the Dr. Sivanna of Earth-5 takes exception to being called 'mad'. He sees himself more as a radical genius.

* The Ultra-Humanite (arguably comics' first supervillain) who actually transferred his brain from the standard baldie-in-a-labcoat mad scientist's body into that of a beautiful woman. He was only another Mad Scientist in the [[TheGoldenAgeOfComicBooks Golden Age]] comics, but in the series ''TheGoldenAge'', he becomes the arch villain, but [[spoiler:[[VillainWithGoodPublicity poses as a hero and gets the medal of honor]]. He saved Hitler's brain, too. And put it in an invincible super-body]].
* D.A. Sinclair of ''ComicBook/{{Invincible}}'' is easily one of the most sadistic mad scientists in fiction. He started making zombielike techno-organic minions, Re-Animen, from dead bodies, which is bad enough. But he eventually moved on to ''live'' subjects, kidnapping his roommate and ''tearing out his vocal cords'' so that he couldn't scream while he operated on him (D. A. is a college student, after all, and can't afford anesthetic). And he tore his arm off and overrode his free will. Then he started duplicating the process on homeless people. Naturally, the US Government saw to it that he served no jail time when he was caught, and gave him a cushy job making Re-Animen for military use.

* In ''YTheLastMan'' geneticist Dr Allison Mann claims she was illegally cloning a nephew who needed a bone transplant. She later admits this story was fictional to gain Agent 355's sympathy rather than be thought of as a 'mad scientist'; her actual motive was to spite her father who was nearing success in cloning the first human. [[spoiler: After several red herrings we encounter the REAL mad scientist is in fact Allison's father, who was seeking to clone his daughter so he could be a better parent the next time round, yet who also sabotaged Allison's cloning experiment out of sheer spite and may have accidentally caused the plague that all but wiped out all males.]]

* ''ComicBook/{{Runaways}}'': Chase's parents, Victor and Janet Stein are a pair of these.

* Profesor Bacterio from ''MMortadeloYFilemon''. Both T.I.A. agents have ''very'' good reasons to run really fast when ordered to test one of his inventions.

* Several villains in the BlakeAndMortimer comics fall under this trope. The most notable being:

* ComicBook/TransformersAllHailMegatron makes Brainstorm into one. He seemingly has no qualms about [[spoiler: putting suggestion ideas inside Kup's mind]] at Prowl's request to exert more control over the army. In ComicBook/TransformersLastStandOfTheWreckers Brainstorm works at the Kimia Facility, an R & D lab full of mad scientists. And Brainstorm in particular is considered especially insane even by ''their'' standards. He makes a hobby of creating weapons so horrible, they're classified as unmentionable by the Ethics Committee. In ComicBook/TransformersMoreThanMeetsTheEye he builds all sorts of weapons [[spoiler: and a holding cell]] for the crew [[spoiler: and to hold Overlord]], including a gun designed to shrink people, a bomb designed to break the fourth wall, and a overpowered laser gun labelled My First Blaster (complete with flashing lights and sounds). Tellingly, when someone asks him about one of his inventions snuffing out a sun, he dismisses it as "filthy, stinking lies"... because they got a small detail wrong.

* The ''Generation 1'' comic ComicBook/TransformersAllHailMegatron makes Brainstorm into one. He seemingly has no qualms about [[spoiler: putting suggestion ideas inside Kup's mind]] at Prowl's request to exert more control over the army. In ComicBook/TransformersLastStandOfTheWreckers Brainstorm works at the Kimia Facility, an R & D lab full of mad scientists. And Brainstorm in particular is considered especially insane even by ''their'' standards. He makes a hobby of creating weapons so horrible, they're classified as unmentionable by the Ethics Committee. In ComicBook/TransformersMoreThanMeetsTheEye he builds all sorts of weapons [[spoiler: and a holding cell]] for the crew [[spoiler: and to hold Overlord]].

* Hank Pym (a.k.a. {{Ant-Man}} a.k.a. Giant-Man a.k.a. Goliath a.k.a. Yellowjacket a.k.a. The Wasp). Just take for example his origin story:

** In the reboot "Pikappa" we have Vendor:however he is much less concerned about creating dangerous inventions.

* Everett Ducklair,the creator of [[ArtificialIntelligence One]] and many of the gadgets [[PaperinikNewAdventures Paperinik]] uses,is a unwillingly case:because of his ScienceRelatedMemeticDisorder,he simply can't create something without turning it in a weapon.He eventually retreat in a monastery to meditate and search for the better part of himself.

* Barry Ween, the 10-year-old with a 4-digit IQ in the eponymous series ''TheAdventuresOfBarryWeen''. A representative quote: "Hey -- put that down! That's the controls to my weather satellite! You just flooded Norway!" [short pause] "Well... it's only Norway..."

* Zorglub, from SpirouAndFantasio, is one. Champignac is often seen as one by the villagers, and he actually ''behaves'' like one on occasion.

* Professor Merson, an American scientist working for Germany, was the source of countless [[StupidJetpackHitler Nazi superweapons]] (including the [[MonowheelMayhem War Wheel]]) in the 1982 ''{{Blackhawk}}'' revival.
** It can be hard to tell -- ''{{Blackhawk}}'' seems to feature gadgetry unbelievably ludicrous enough to fall under mad science in every issue, and frequently right on the cover.