Diagnosed by the Audience: Fred. It's never outright confirmed, but he doesn't disagree when Harriet accuses him of being mildly autistic and shows enough self-awareness about his innocent insensitivity to suggest that if he is, he's far to the high-functioning end of the spectrum.
Harsher in Hindsight: Fred's already-failing marriage going down the drain due to his burgeoning feelings for Harriet becomes harsher after Ewan McGregor fell in love with Mary Elizabeth Winstead while filming Fargo and divorced his wife to be with her.
Memetic Mutation: People love to make fun of the title due to how strange and awkward it sounds and how much it's name-dropped in the movie.
Unintentionally Unsympathetic: After Harriet's soldier boyfriend Robert turns up alive, Fred admits to him that he loves Harriet. Robert sarcastically comments "well I'm sorry I'm not lying dead in a ditch somewhere," to which Fred remarks "so am I." Although Fred apologizes for it immediately afterward, saying that he was just joking, he seems less than sincere.
