These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Tear Jerker: "Johnny Freak". Johnny is a deaf, abandoned child without legs, found by Dylan. The child displays amazing intelligence (he learned how to read lips and to speak, albeit badly) artistic abilities, and forms a bond with Dylan and Groucho. Then things go downhill as his origins are revealed: he's the illegitimate son of the Arkham family, born deaf but otherwise healthy, while his legitimate brother Dougal was born with a degenerative illness. The Arkhams then used Johnny's organs and limbs to replace his brother's when they started failing, while otherwise keeping Johnny trapped in the basement. For years. How the story ends? Dougal shoots Johnny because he loathes him as a "freak", then has a heart attack. As Dylan is at Johnny's death bed, Johnny's last request to him is to give his heart to Dougal in order to save him. Dylan almost refuses to do so, but can't bring himself to betray what is effectively his own son.
The Untwist: Lampshaded in an issue where an ex policewoman is haunted by what seems to be the ghost of a criminal she helped capture and execute. When Dylan suggests it may be a twin who wants to avenge his dead brother, Bloch replies he's not heard such a trite idea since '48. In the end it turns out it was a band of six twins.