These are what we call the 'YMMV items.' Things that some people find in this work. We call them 'your mileage might vary' because not everyone sees these things in the same way. This starts discussions in the trope lists, a thing we don't want. Please use the discussion page if you'd like to discuss any of these items.
Even after the manga's end this is still the most popular ship.
Die for Our Ship: Keita is too popular a character to really have this trope apply to him but more than a few will ship him with anybody but Ichiko. Several fans have said, "I don't care who he ends up with as long as it is not Ichiko."
She does get better anyway. Her former butler is living peacefully (with a new wife) as he writes her letters often. Later, she has become more sociable as she befriends a delinquent tomboy who vows to never betray her and probably a Cosplay Otaku Girl goddess.
Akane also counts in that her hate of Ichiko seems to stem only from jealousy of Ichiko's popularity. After Ranmaru saves her and her friends from a collapsing building Akane seems to actually regret going too far, if only cause Ranmaru got hurt. She and her friends call an ambulance and lead them back. Later its heavily implied that not only is Akane in love with Ranmaru but that Ranmaru may have been a Closet Key for her causing her more than a bit of angst. She still hates Ichiko, but for different reason now.
And later, Ikari's revealed to have suffered a lot before. It turns out he was born the exact opposite of Ichiko, with a massive amount of bad luck, that made him a pariah even though the bad things only happened to him. The one person who was willing to be with him, like him and even eventually love him dies saving him. Made worse because she saves him by turning him into an immortal god effectively making him have to live forever without the person he loves and with the pain of her loss.
Les Yay: The Manga is so full of les-yay that Tsuwabaki is the only reason it's not Yuri.
Lampshaded in chapter 32
Ranmaru: "How dare you to make my precious Ichiko cry...!!!"
Nadeshiko: "Don't say things that'll be taken the wrong way! It's bad enough that we're being mistaken as a yuri manga by some readers."
When Momiji and Ichiko are teleported to Antarctica by mistake (it's a long story) Momiji suggests huddling together for warmth which is logical under the circumstance. She then suggests that they huddle together naked which is...less so. Of course, she might have been doing that just to mess with Ichiko's head.
Chapter 51 starting about here, ends in a way that make it seems that Ichiko and Momiji are an Official Couple.
After Their Fusion Dance, Momiji gets a lot of enjoyment out of feeling their combined body's bust and they sound like a arguing couple when they switch control.
Ichiko and Ranmaru within chapter 25. Also taken Up to Eleven in the omake. And then there's the final scene of Episode 8 where Ichiko finally accepts Ranmaru as her friend. While not really Les Yay, it almost looks like it.
Ichiko even kinda confesses to Ranmaru at one point. To be fair, she's essentially drunk at the time.
She also for some reason has a bunch of sexy pictures of Ranmaru.