- Actor Allusion: The third season Christmas Episode is called in which Max believes an autistic child is communicating a message from his son is called "Samuel Rising." Miko Hughes, who appeared as an evil alien in three episodes of the second season, played the autistic child in the movie Mercury Rising.
- In "Viva Las Vegas," Michael gives everyone drink themed aliases for their fake IDs. Alex, played by Colin Hanks, son of Tom Hanks, gets the alias Tom Collins.
- Dawson Casting: Jason Behr was 26 at the start of the show.
- Hey, It's That Guy!: Hey, it's Izzie Stevens back when she was a teenage alien! They even have the same first name!
- McLeaned: Alex, after Colin Hanks left the show.