Trivia: Mortal Kombat: Annihilation
- Fan Nickname: Get into any discussion of Mileena online and see how long it takes someone to refer to her as You Wish.
- Franchise Killer: There were plans for a third movie follow up, but disappointing box office returns saw them fall by the wayside. Years later, there were serious talks of a new movie, that may or may not have been a true sequel, but production difficulties led to it being scrapped.
- Hey, It's That Guy!:
- The Other Darrin: Done with several of the main characters. The only actors from the first film to return for the second were Robin Shou (Liu Kang) and Talisa Soto (Kitana).
- Aside from them, only one actor returned for this movie, this being stunt double Keith Cooke. Only, while he played Reptile's ninja form in the first movie, here he plays Kuai Liang, a.k.a. the little Sub-Zero brother.
- What Could Have Been: Just like the first movie, Michael Jai White was slated to portray Jax. Ultimately, he turned down the role, this time to do Spawn. He finally portrayed Jax in Mortal Kombat: Rebirth and Mortal Kombat: Legacy.