This is based on opinion. Please don't list it on a work's trope example list.
Tear Jerker / Interesting Times
When I heard about what happens to Twoflower's wife, I had to sit down for a little bit because I'm quite a bit like Twoflower, and I know exactly how much that would hurt.
It is the only time Rincewind has ever seen Twoflower look anything other than happy, contented and trusting. Later, of course, he challenges the villainous Lord Hong to a duel to the death as payback — which is also highly out of character for Twoflower. And as we all know, OOC Is Serious Business.
"I have two dutiful daughters." That just broke my heart.
It's been a long time, care to provide context?
Here's the context in question:
"Rincewind: 'I was, er, I was sorry to hear that your wife, eró'
Twoflower: 'Things happen in war. I have two dutiful daughters.'
Rincewind opened his mouth to say something but Twoflower's bright, brittle smile froze the words in his throat."
The fact that Twoflower's wife was basically caught in a crossfire just makes it even more heartbreaking. It made me think of battles in Real Life, and how civilians end up suffering the horrors of a war they probably never wanted.
Shockingly, this troper got one for Lord Hong. Having spent virtually all his life as The Ace in whatever he sought to do and essentially controlling the Empire by proxy, his ultimate goal is to rise to power in Ankh Morpork and play chess with the Patrician. He even spent months having spies travel to the city, carefully ordering specific pieces of clothing until he had a complete set of clothing that fit the description of a Morpork noble. Amidst his detachment from virtually everything else, Hong literally trembling with anticipation as he periodically tries on the clothes is...heartbreaking. For all the evil he's done, he practically becomes a tragic villain when you realize that he's been The Ace ever since he could walk and talk, but it doesn't matter when the populace of the Empire will grovel at the feet of anyone with a horse. He wants nothing more than to rise to power in a city where he has to earn his respect by his own merits. This troper was glad that he got a painless death, because frankly, he's practically a Dark Lord in Ravenloft.
When you think about it in those terms, dying before ever getting to Ankh-Morpork is the best possible thing that could have happened to him, because the book points out that there's no way he could get to the top solely on his own merits. Being The Ace in a culture that has stagnated as much as his has wouldn't translate into the practical skills necessary to survive in Ankh-Morpork. He'd have to buy his way in, which the previous poster has pointed out is exactly what he wanted to avoid.