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Anime & Manga
- In JoJo's Bizarre Adventure: Golden Wind, Passione member Carne acts as a Sacrificial Lamb to activate his Stand, an indestructible Blob Monster called Notorious B.I.G (oddly pronounced "big" instead of "B-I-G"), that swallows and absorbs anything in its path while being attracted to the fastest-moving object in its vicinity. In particular, the need for its user to die before it activates seems to specifically be a reference to Life After Death.
Film — Animated
- In the Novelization of Turning Red (which is called The Real R.P.G.: The Story of the Red Panda Girl), Mei's mother is referred to as the "Notorious M.I.N.G." at one point.
Music
- The Notorious B.I.G.'s "Juicy" references the battle between the Super Nintendo and Sega Genesis in the Console Wars, and is often given a Shout Out:
- A$AP Rocky, New York Bittersweet Symphony
- Chris Morris, Super Nintendo samples "Super Nintendo, Sega Genesis" from The Notorious B.I.G.'s Juicy.
- King Chip, Dear Hip-Hop
- Minority$ociety, DreamsWho know the old days can change the way you think
No taking it for granted, could be gone in a blink of an eye
Now it's too late, click rewind
Back to my Super Nintendo, Sega Genesis days. - Snoop Dogg, Santa Claus Goes Straight to the Ghetto:
- Spose, Why Am I So Happy?When I was six, my biggest worry if I can reminisce
Was that I'd have a Super Nintendo but not a Genesis - Teiji Mack, Cigarett TripsFull crib, Super Nintendo, Sega Genesis
Back then the buttons for the Hadouken, seemed limitless
Pressing anything to hit a fatality - Too Far Boyz, Juicy ;)
Theater
- The song "Ten Duel Commandments" in Theatre/Hamilton is a whole song reference to "Ten Crack Commandments"
Video Games
- One boss in Crypt of the NecroDancer is a rapping mole named Fortissimole. His battle theme, which he raps himself, is called "Notorious Dā.āIā.āG.".
- In Splatoon 2: Octo Expansion, the rapper Pearl wears an outfit that appears to be a tribute to Biggie Smalls, complete with a gold crown and chain necklace. Appropriately, her partner Marina wears an outfit reminiscent of Tupac Shakur.
Web Original
- Buzz Feed Unsolved has an episode where Ryan, Brent, and Daysha discuss his death and some of the theories behind it.
- From the Thunder and Friends episode, "With Friends like Cody's".Junior: Wanna play video games? I have the Super Nintendo!
Cody: And Sega Genesis?
Junior: I hate Sega.
Cody: Oh.
Western Animation
- American Dad!: In a flashback from "Brains, Brains and Automobiles", it is revealed that Biggie got shot because Roger, who was driving him around, insulted another driver for cutting him off and used Biggie as a Human Shield before making off with the gold necklace he was wearing.Stan: (takes the bling out of his shirt) He said he made this for me.
- Futurama: In "The Luck of the Fryrish", a flashback to Fry's past features a beatboxer called Noticeably F.A.T.
- South Park: In "Hell on Earth 2006", Butters tries to pull off a Bloody Mary stunt by chanting "Biggie Smalls" before a mirror. Biggie appears and tries to kill him because people have been doing the same thing all night and making him leave Satan's party.