Orlando, from The League of Extraordinary Gentlemen. Being a chronic sexual-shifter with hundreds of years under his belt helps it. He's a violent and sexual being. As the comics themselves say, "Orlando has slept with absolutely everyone, and those he hasn't slept with he has waged terrible war against."
The entire premise behind one Jerry Siegel's most obscure creations—Jon Juan,Super Lover.
Artesia has sex with no fewer than nine different men on-panel, several of them simultaneously. Nobody seems surprised by this, at least in her native Highlands where it's accepted. In the Middle Kingdoms, where the sexually-repressed Divine King religion holds sway, not so much.
In Persepolis, Marjane's friend, Julie, mentions that she had sex with 18 boys (and later has sex with another one). Marjane fled from Khomeini's Iran and doesn't like his "everything in the west is decadent" ideology, but now finds herself shocked too.
Marjane herself is seen as this by her friends upon returning to Iran because she's been with more than one man.
The title character of Nikolai Dante has an entirely deserved reputation for this, not that any of the women mind. He (mostly) stops after officially getting together with Jena.
This trope applies to the superhero community as a whole, as the vast majority of them abuse their fame and power and become sexual deviants to the point where they hold an annual drug-fueled orgy called "Herogasm". And unlike Maeve, not all of them bother looking for consent.
De Kiekeboes: Fanny, the 18-year-old daughter of the family. She has had countless boyfriends over the course of the series. It is lampshaded by herself that she has to dump them at the end of each story to make room for the next one in the next story. Only one guy, Jens, stayed with her for longer than one album, but eventually even that story arc got axed. Creator Merho said: "My readers couldn't decide whether he should have stayed with her or not, so whatever I did I would've created a Flame War." In a bit of a subversion, however, it is implied on several occasions that she actually doesn't sleep around a lot, but simply has a lot of dates.
The Italian comic Rat-Man (1989) has Clara, Brakko's wife. Their exact number is unknown, but when Clara called all of them to rescue Rat-Man, Brakko and their allies from The Shadow's army of monsters she showed with an army. After that battle Brakko and Clara decide to go to a marriage counselor to try and salvage their marriage... And Brakko catches her cheating on him with the marriage counselor. This leads to their divorce.
Surprisingly Averted with Cinzia, the (male-to-female) transgender hooker: while she's a raging pervert and has slept with many men including much of the police department (giving her a lot of ammo when the cops started mocking her for being trans), the ones she slept with were exclusively for the job, and outside it she only tried to sleep with Rat-Man, with whom she's been openly in love for most of the comic, and later Brakko, and was willing to leave her job if she ever managed to get with either of them.
Italian graphic novel Venerdì 12 (from the same author as Rat-Man above) provides what may well be the ultimate example with Bedelia, a shallow woman who has slept with so many men (and at least one girl) that she has to call them by the number they have tattooed inside the thigh. The highest known number is 322. She also went with the protagonist Aldo because she had bet she could do all guys in her high school in five years (by the way, she lost: Aldo was in love with her and incredibly shy, and when she finally tried he locked himself in the toilet. She dumped him for that). And then, the sequel Bedelia shows that not only she literally had sex with half the men in town and was aiming at everyone but Aldo, she even had sex with a horse and her own guardian angel, repeatedly (leading to him being replaced with one who isn't into women). And then, after dying her ghost ends up having sex with Aldo's son. The sequel casts Bedelia in a more sympathetic light than most, however, as it shows she's so lonely she pays people to be her friends, cannot realize one of her friends isn't in for the money, and has a horrible relationship with her mother, and is trying to fill the void in her heart somehow.
Archie from Archie Comics is this Depending on the Writer, though, according to a 1970s issue, he's actually celibate despite all his success with the ladies. On top of his love triangle involving Betty, Veronica, and sometimes Cheryl, he's had numerous other love interests. There are also numerous off-hand jokes about him and girls, including how he has dozens of girl's phone numbers.
Lori Lovecraft enjoys a very active sex life. The narration in Into the Past even Lampshades the number of ex-boyfriends she has.
Fine Print: Lauren has lots of casual sex to assuage her sadness, and is shown in many different encounters. All the Cubi are promiscuous as well, naturally, with providing sex to humans being their literal job. They also have group sex with each other and Cupids.
Shortcomings: Alice is very promiscuous. Ben bonds with Sasha at a party over being two of the few people there that she hasn't ever gotten with.
Super Lover.