This is based on opinion. Please don't list it on a work's trope example list.
Nightmare Fuel / The Invisible Man
The central idea: a villain has made himself invisible. You don't know he's coming until he's got his fingers around your throat. And he is furious. The scene where a man who was forced to help him runs panicked into a town screaming, "The Invisible Man is coming!" is still disturbing.
Griffin's ferocious temper and megalomanic insanity, coupled with his invisibility, produces a frighteningly unpredictable package. He ends up with the highest body count of any of the classic Universal Horror monsters, as well as most horror movie slashers, most of which he does for no reason at all.
The care facility for insensates, people who lost most or all of their senses due to invisibility research. Particularly memorable is a man who keeps cutting himself with a shard of glass, implying that pain is the only thing he can feel anymore. When Darrien takes the glass away, the man desperately gropes around for it.
In "Tiresias," Hobbes is attacked by a Quicksilver-mad Darien. Hobbes tries to call for help from a phone booth, as an invisible Darien smashes the glass and tips it over before trying to strangle him.
In the pilot, Darien wakes up in the middle of night, feeling what later turns out to be Quicksilver Madness. It's pretty unnerving to listen to his description of what he's feeling while looking at himself in the mirror in the dark.
"It was as if someone was knocking at the backdoor of my brain—something that wanted in real bad. Staring into that mirror, I had the sudden, horrible feeling that another person was looking back—a stranger that had stolen my face."