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Manga: Tubame Syndrome
Another entry in the long list in the Harem genre. The story follows Taiga, an ordinary high school student, and his sister Tubame. Taiga cannot remember anything up to a few years ago and relies on Tubame to take care of him after an accident that he cannot remember killed their parents.

Can be read here
This anime provides examples of:
Tsuyokute New SagaMangaTuxedo Gin

alternative title(s): Tubame Syndrome
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