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Anime and Manga
- xxxHolic: The heroes go about, helping addicts of various types.
- In Ballad Of A Shinigami, Momo the shinigami finds some way to relieve the pain of the dead or the ones they are leaving behind each week.
- Tokyo Babylon has A LOT of these.
- Princess Tutu is mostly this sort of thing in the beginning, with the heroine helping people solve their issues through dancing.
- Basically, every other One-Shot Character in the Sailor Moon anime is one. It get annoying after a while, as the Senshi are perfectly fine helping out the character they barely know, but they spend no time with their actual friends. Remember Naru? Usagi probably does not.
- Mushishi combines this with Mystery of the Week. Most episodes feature people in incredibly unfortunate circumstances due to the effects of various mushi. Then Ginko arrives, figures out what kind of mushi he's dealing with and sees if he can help. Sometimes, he can't.
- Hibiki no Mahou has these, one of whom is Hibiki herself.
- Characters in Paranoia Agent are this, except most of them don't get happy endings, while others receive Gainax endings.
- Each Hell Girl episode would focus on various troubled characters who is tormented by someone else, and how they are eventually driven to make a Deal with the Devil to send their tormentors to hell.
- This trope is one of two main gimmicks of Yamada-kun and the Seven Witches, along with Magic Kisses. Every arc revolves around at least one character with a hard life - usually one of the titular witches - that Yamada needs to help. The series is not afraid to play the Jerkass Woobie card, though - many of the woobies of the week are rather uncooperative or even villainous until Yamada finds out what is troubling them and gets through to them.
Live Action TV
- Highway To Heaven
- Touched by an Angel
- The similarly-premised Twice in a Lifetime, where an angel allows a one-shot character to revisit a moment in his life when things started going wrong.
- Wonderfalls: A bunch of animal figurines that may or may not be God annoy heroine Jaye into helping strangers on a weekly basis.
- Joan of Arcadia: Joan helps a new stranger every week at the suggestion of God himself.
- Ghost Whisperer: "Distressed ghost who refuses to pass on" of the week.
- On Fantasy Island, each week a different group of guests come to the island and learn some sort of life lesson
- The Love Boat likewise has a new set of guests every week, all of them looking for love on the cruise ship.
- Quantum Leap has this built into its premise: Bakula jumps into a new body every episode, and that person, or someone around him, is always in distress. The series catchphrase, his mission, is to Set Right What Once Went Wrong; once that's accomplished, he leaps into the next body. It's heavily implied to be the result of divine intervention.
- 21 Jump Street, the episode where the cops go undercover and there's this chick who's all introverted but seems to know about the crimes that are going on, and she's all disturbed. Turns out she's psychic.
- Season 4, an episode called "Haunts in a New Age"... A psychic teen says she can predict when an arsonist will next strike during a Halloween dance.
- Kamen Rider Fourze has an interesting twist on this, combining Monster, Victim, and Woobie of the Week into a single package. The MOTW is created by a human "Switcher" using a device called an Astro Switch; the Switcher is someone with a grudge who's so hell-bent on revenge that they're blinded to the fact that the Switch will eventually kill them. So instead of just beating up the MOTW, Fourze and his team reach out and try to befriend the Switchers so that they know there's somebody who cares.
- Its predecessor Kamen Rider Den-O had a similar format where the Monsters of the Week were Jerkass Genies who took the Victim's wish and warped it for their own ends, usually Woobie-fying them in the process. Protagonist Ryotaro would try to help the victims, initially taking some flak from some of his allies who insisted his only job is to protect the timestream, but his response was that helping the victims was part of that job too.
- Burn Notice — not every episode has Mike and the others helping someone in need, but many do, particularly in the first few seasons. The standard formula is Two Lines, No Waiting with the Woobie being the A Plot and the progress of the Myth Arc being the B Plot, or sometimes vice versa.