Inferno may refer to:
- Hell - a place where damned souls go after death in some western religions
- The first part of the 14th century poem, The Divine Comedy, by Dante Alighieri
- The fantasy novel, Inferno by Larry Niven and Jerry Pournelle.
- Inferno, the second novel in the Indigo series by Louise Cooper.
- Inferno, the sixth novel by Dan Brown.
- The action movie Desert Heat, which alternative title is Inferno.
- The horror movie, Inferno, by Dario Argento
- The Marvel Comics crossover comic, Inferno
- The user-developed game-mod Inferno for FreeSpace 2.
- The Third-Doctor era Doctor Who episode Inferno.