In issue #2, Harley and Poison Ivy free all the animals in an animal shelter that permits euthanization and turn Harley's studio into an indoor park to keep them there.
Harley gives Big Tony the last love berry from Ivy's plant to help him win back his girlfriend Queenie on Valentine's Day. Sure, it does backfire (because the berries are loaded with pheromones), but you can't say she was trying to screw him over considering the idea was helping him get together with Queenie.
The fact that Ivy has left Harley some medicinal plants at her apartment. The signs on them show that they can cure pains and upset stomachs. In fact, most of Harley and Ivy's interactions are pretty sweet.
Harley meets Bruce Timm and Paul Dini, her literal creators, at Comic-Con.
Harley meets a beluga whale. Much cuteness ensues.
Harley will, from time to time, team up with or run into various superheroes through variously contrived circumstances (the list includes Power Girl, Wonder Woman, Batman, and Green Lantern). At least most of the time, the heroes compliment her on trying to do good, even if the results of her efforts vary.