Crowning Moment of Funny: Listening to polite, cutesy Sarina interject "fuck", "eat shit", and "sons of bitches" into her daily speech just has to be heard to be believed.
The events leading up to the Bad End where Masayuki Onda becomes a transsexual. Actually, Masayuki Onda's interactions with Shikanosuke (or rather, Shikako) are loads of this.