Take a shot whenever:
- Luna quotes song lyrics.
- Lori says the word "literally". Two if she actually uses it correctly.
- Lucy creeps up on someone.
- Lucy talks about poetry.
- Lucy says sound effects out loud.
- Leni uses the word "like".
- Luan makes a pun. Take an additional shot if she doesn't say, "Get it?" afterwards.
- Lily goes without her diaper.
- Leni takes something too literally.
- Just take a sip whenever Leni does something stupid.
- Take another sip every time Leni walks into a wall.
- Just take a sip whenever Leni does something stupid.
- Lola loses her temper.
- Lori is angry.
- Lincoln gets annoyed with his sisters' antics.
- Luna calls someone "dude" or calls Lincoln "bro".
- Luna says, "bogus" whenever something goes wrong.
- Mr. Loud starts blubbering.
- Lori or Bobby starts crying. Take two if Lori and Bobby do it together.
- Anybody says, "Dang it." (Note: Do NOT try this during "Homespun.")
- There's a Flashback.
- Someone breaks the fourth wall and talks directly to the audience. Two shots if it's not Lincoln.
- The episode ends with one or more of the Loud children apologizing for their behavior.
- Two shots if a different character apologizes at the end of an episode.
- Down two shots whenever Mr. & Mrs. Loud don't intervene when you'd think they should.
- Just down the damn bottle if they don't even notice what their kids are up to.
- Clyde falls for Lori.
- Take a shot for Clyde acting wired while Lori’s around.
- Two shots if he sees Lori and doesn't act wired. (Note: This gag is mostly dropped in Season 3, and completely forgotten about from Season 4 onward, so it's advisable to only take this seriously during the first two seasons.
- Take a shot for Clyde acting wired while Lori’s around.
- Lily says, "Poo-poo."
- Whenever the stock guitar riff used for scene transitions plays.
Take a drink whenever:
- Lincoln gives an overly long and specific name to an emergency plan, the notes it needs a shorter name.
- Any of Lisa's experiments go haywire.
- Lincoln says, "In a family as big as mine" or a similar expression.
- Lynn turns anything mundane into a sport.
- Luna speaks with a British accent or makes a musical reference (which isn't a direct quote, as that's covered above). Take two if she does both at the same time.
- Take two if it's Lynn Sr. who's speaking in a British accent.
- Lily poops in her diaper.
- Luan pulls a prank (WARNING: Don't watch any of the April Fools Day episodes if you value your health!)
- The Louds do something that gets them all grounded.
- Lola says, "I'm telling mom/dad!" (Mild warning for "Sleuth or Consequences", which has multiple in less than a minute!)
- Lisa claims she doesn't normally express human emotions, but follows it with a squeal or tears.
- Lucy talks about Edwin or vampires. (Though beware of the episode "Fandom Pains" if you use this rule...)
- Lana pulls something out of Hammerspace.
- Lori calls or talks in person to Bobby.
- One of their pets is acting unlike their species.
- Lisa's poop study is mentioned.
- Luan says, "But seriously."
- Clyde or his dads act neurotic.
- Lincoln is in his underpants.
- There's a fart or burp joke.
- Lana does something for the animals at the expense of everyone (Avoid episodes like "Frog Wild" and "Scales Of Justice".)
- Lori paints her toenails.
- Ronnie Anne pranks Lincoln.
- Someone does lucha libre.
- Rusty gets comical hurt
- Lynn does a crazy good luck ritual.
- Someone says the Episode Tagline (eg "No musica!" in "Save the Date" or "Five minutes" in "Attention Deficit").