It's Michiru Yamane (and Vincent Diamante), so that's to be expected:
- Anti-Skullgirls Labs: Paved With Good Intentions, a dark, tense track that can make you feel like an Evil Genius.
- Maplecrest: The Lives We Left Behind. Also used as Painwheel's leitmotif, so bonus points for Soundtrack Dissonance. Gets a heartbreaking Dark Reprise in The Lives We Tried to Reclaim.
- Under the Bridge: Unfinished Business. This theme usually gets flagged for having too much SAXUAL content!
- NMO Arena: "The Crowd Goes Wild" will get you hyped for Wulfamania!
- Bath of Tefnut: An Oasis in Time is an elegant theme with a sense of antiquity. Its Dark Reprise, An Oasis of Blood, is much more dramatic and menacing. It really helps to showcase Eliza's dual nature.
- Boardwalk: Ice Cream Headache, a lively, bubbly tune fitting the boardwalk amusement park setting of Umbrella's stage. This track is also notable for being the first track not to be directly composed by any of the main composers, instead being composed by guest composer Raito of Melty Blood and Under Night In-Birth fame.
- New Meridian Rooftops: Clear Breeze, an upbeat-turned-dark theme with a motif from Moonlit Melee. And then when the night falls and things go to ruins, comes...
- Rooftops Assault: Destiny in Her Hands, with its One-Man Wail. Shares a Recurring Riff with...
- The final boss theme, Skull Heart Arrhythmia reprises the One-Woman Wail from the opening song but makes it much more frantic and intense, fitting for the climactic encounter with the Skullgirl herself.
- Hilgard Castle: All That Remains samples the Skullgirls Theme itself(!) to make a epic piano piece for Marie's own leitmotif.
- The ending credits theme, In A Moment's Time, with vocals by Geila Zilkha, is a terrific throwback to jazzy love songs... though astute listeners might notice the Lyrical Dissonance: the song is from the perspective of the Skull Heart itself!