Archie Comics: "Big" Ethel Muggs was originally created to facilitate this punchline. She was attracted to Jughead, who was notoriously uninterested in anything but food.
Archie Comics have also downplayed this aspect of Ethel in later years. While she was as ugly as they come in her first appearances and used solely to torture Jughead, Ethel has since had some of her more distorted features toned down. She's still really tall with buck teeth and a big nose, but she's drawn much more normally — even pretty — and given trendier clothing. As well, she's more of a regular character now (being good friends with Betty), instead of a one-dimensional plot device.
Subverted again in that Archie took her out on a casual date to a comedy club and museum and ended up preferring the fact that unlike Betty and Veronica, Ethel made no demands of him. He asked her out again after taking her home.
Inverted in an issue where Cheryl Blossom tries to seduce Jughead, just to prove she can. She fails but then sees Jughead trying to impress Ethel (who unbeknownst to Cheryl had a picnic basket full of food). Later on another character decides to practice some lines for a play, and Cheryl walks in on him apparently declaring his love for Ethel. The issue ends with Cheryl taking a photo of Ethel into a beauty parlor and demanding to be made to look "like this exotic creature".
Brigitta McBridge toward Scrooge. For a change, Scrooge has no problem with her personality, and it's hinted the only reason she's unwanted as a romantic partner is that he's still in love with "Glittering" Goldie O'Gilt.
Princess Oona is this to Donald Duck. During a trip to the Stone Age in Gyro Gearloose's time machine, Gyro and Donald Duck first meet the incredibly strong cave-duck Oona. On the journey back to the future she stows away in the time machine and has remained in Duckburg ever since. She falls madly in love with Donald and uses her enormous strength to hug him and kiss him against her will. She knows he dates Daisy, but she doesn't care.
A story titled The Sanctuary Tree ("Love is in the Air" and "The Potion of Love" in foreign translations) begins with Donald being chased by a tall, fat, strong, angry and ugly female redheaded officer... because Donald was fishing in a forbidden area. Donald manages to escape her, not without insulting her first but is late for a date with Daisy. Furious, Daisy ends the relationship. Then Donald buys a love potion that causes the victim to fall in love with the first person she sees in front of her. A series of incidents culminates in Donald and Daisy ending up in the same lake at the beginning of the story, with the same fat female officer taking the potion and falling madly in love with Donald. She immediately and tightly embraces Donald, kissing him nonstop, to his horror and disgust. Daisy sees everything and believes they are lovers. She leaves screaming that she never wants to see Donald again, leaving the couple continuing to kiss. Donald finally manages to break free of the woman's embrace, and the story ends with him hiding in a tree while the female officer waits for him on the ground, making promises of love.
Herbie has Tinklepuss the cavewoman and Hepzibah Higgins. Also, Herbie is not particularly fond of women in general, but he particularly despises fat or ugly ones.
Invincible: Mark has had at least two women who fit this in his life:
He was once almost forced to marry the princess of Atlantis (in this version of Atlantis, merpeople are half-fish all over their bodies, like a Lovecraftian horror). Subverted in that the princess would rather marry one of her race and with a cunning plan, Mark escapes to the surface and she happily marries a more suitable groom.
Anissa, however, as a more traumatizing example. Wanting him as her mate due to being part-Viltrumite, Anissa attempted to seduce him, but when she was rejected she reacted by attacking him before raping him. Since the incident, she became more interested in him, causing him nothing but fear and discomfort. While he never really forgave her after she came to regret that decision, he does at the least get along with their son.
In a rather dark example, in Mark Waid's Irredeemable it's revealed that Modeus is this to the Plutonian. At first, the Plutonian finds it amusing but eventually turns ugly as Modeus is more than willing to beat the crap out of him and super-rape him.
Played with in Justice League Europe with Crimson Fox's ongoing sexual harassment (really, there's no better description) of Captain Atom. Interestingly, Crimson Fox is drop-dead gorgeous (and has pheromone-based mental manipulation powers to boot). It's really the fact that she comes on very strongly, and that she makes it blatantly clear that she is only interested in him physically and could not care less about his feelings.
The Madballs comic book published by Marvel Comics subsidiary Star Comics had Dr. Frankenbeans' assistant Snivelitch experience this trope on both ends. The beautiful sorceress Miss Tic the Mystic is disgusted by his affections, while he himself was in for the shock of his life when the female Madball Madbelle confessed her love for him.
Mélusine: In the early albums, an undead mummy living in the Castle obstinately tries to woo Mélusine. She's seriously annoyed by him.
Mickey Mouse Comic Universe: In one story titled The Ice Princess, Mickey and Minnie are skiing when he accidentally ends up in a magical kingdom where all the inhabitants are made of ice. He discovers that one of the inhabitants will be forced to marry the princess of the kingdom, otherwise a curse will fall on the other inhabitants. Since the princess is arrogant, spoiled, and cruel, Mickey tries to help the chosen man seduce her by creating a beautiful speech for him to recite to her. Unfortunately, the princess eventually sees Mickey rehearsing the speech aloud and she falls madly in love with him. As soon as she is alone with him, the princess hugs him tightly and tries to seduce him, even saying they will get married the next day, to Mickey's horror. The princess is beautiful but taller than him, and in addition to her unpleasant personality, the fact that her body is made of ice makes Mickey shiver in the cold when she embraces him.
Mortadelo y Filemón: The overweight Ofelia, to Mortadelo. Mortadelo's sister to Filemón in the second movie.
The Mexican comic Simon Simonazo used this trope in a rather strange manner; the Admirer in question had a comically horrid face, her body on the other hand...
Red Daughter of Krypton: Worldkiller-1—a body-snatcher enemy which is an alien, sentient goo—is this to the titular heroine. Although it isn't interested in Supergirl romantically, it will not stop talking about wanting her body and them being made for each other, making Supergirl sick.
Worldkiller-1: Can not you see that both of our lives have led to this union? Supergirl: Stop. Just stop. You make us sound like lovers, and it's turning my stomach.
Mr. Mxyzptlk to Supergirl in Action Comics #291. She makes clear she cannot stand that stupid, reality-warping, imp-looking prankster who thinks he is funny. Mxy's reaction was popping the question◊.
Supergirl: I'll tell you what I think! I think you're an irritating, aggravating, annoying pest! I hate you! You're the greatest creep there ever was! Mxyzptlk: My, but you're beautiful when angry! A strange thrill is tingling up and down my itty-bitty spine! It must be... love! Marry me, beloved! Supergirl: NO!! Not even if you were the last man on Earth!
In Bizarrogirl, a bald Bizarro is particularly and openly smitten with Supergirl. Kara is not impressed.
Superman/Supergirl: Maelstrom: The titular villainess is obsessed with Darkseid, even though he makes literally painfully clear that he has no interest in her...or anybody.
Maelstrom:"Mine is not the trivial longing of a small child for her master's favor. I shall gladly face any and all challenges set before me to prove my worth!" Darkseid:"I am bored now. Throw her in the slave pits!"
Power Girl had to contend with Vartox, an alien superhero from the planet Valerion who sought to seduce her and breed a new population for his planet after they were hit with a sterilization bomb. While she was repulsed by him and unwilling to take up this tremendous task, she did help him find a way to cure his people though she made it clear she had no romantic interest in him.
In issue #30 of the original Teenage Mutant Ninja Turtles series, during the story Sky Highway, Raphael gained one with a German mutated human called Hildagaard Rail. In a dimension where there is an actual highway in the sky, Raph fell in the passenger side of her car. She wore sunglasses, had her hair wrapped up in a scarf tied behind her chin, and a black dress that showed off her ample bosom. Hildagaard had long legs and the body of a supermodel, but her lips were so enormous they went from ear to ear and almost from chin to forehead taking up most of the space on her face. She openly flirted with her "dollink" turtle telling him "You're the most sexy shade of green I've ever seen." When Raphael was about to leave her car he told her "It's been funfffh!" The ninja's words were cut short because Hildagaard grabbed him by the tails of his bandanna and said: "Shut up and kiss me, you dumkoff!" With his head tilted all the way to the side she pulled him close to her and gave him a big passionate kiss that covered his entire beak. When he finally got away from Hilda she called out, "Auf Wiedersehen, loverboy!" Raph referred to it as the biggest indignity he ever had to face as a hero. The turtle wiped off the giant lipstick imprint off of his face which wasn't sideways, but on straight making it seem like they locked lips for a while. At least long enough for Raph's head to tilt.
Tom Strong: Ingrid Weiss is one to the titular character. Not because she's unattractive, mind you, but because she's deeply committed to the Aryan ideal, keeps making inflammatory remarks about Tom's wife Dhalua, and took advantage of an unconscious Tom to produce a son.
In Violine, both Violine and her father read the thoughts of a pig that immediately falls in love with them, with some... disturbing images for her father.
◊.Supergirl: I'll tell you what I think! I think you're an irritating, aggravating, annoying pest! I hate you! You're the greatest creep there ever was!
