Fiction loves juxtaposition, and so in fiction, you're likely to come across a character with a disability at odds with their Art, like a one-handed pianist, a colorblind painter, or a one-legged dancer.

May be used to show them as Inspirationally Disadvantaged, portraying them as having to work much harder than their abled counterparts to create good art. Previously abled artists who suffer an injury and keep going might be