History YMMV / WillAndGrace

** A season 8 episode has Will ask, "Where in the world are Matt Lauer's manners?". In 2017, Matt Lauer was exposed as one of many men in entertainment guilty of rape and sexual harassment.
** The RunningGag about Grace's big appetite becomes this when Debra Messing [[https://www.dailymail.co.uk/tvshowbiz/article-8605179/Debra-Messing-admits-way-skinny-Grace.html revealed she felt pressured to lose weight]] during the show's original run.

** Neil Patrick Harris had a guest role in season 2 as a gay guy who had been converted to heterosexuality. Six years later, Harris came out as gay.

** Eric Allan Kramer guest starred in a season seven episode where Leigh-Allyn Baker's character also appeared. The two would co-star later in ''Series/GoodLuckCharlie''.

* HilariousInHindsight: Neil Patrick Harris had a guest role in season 2 as a gay guy who had been converted to heterosexuality. Six years later, Harris came out as gay.

** Julian [=McMahon=] plays "Guy," who chats with Grace in an elevator in Season 1.

** She once had a Thanksgiving hookup with a plumber, at Stan's behest--played by Mullally's real-life husband Nick Offerman, now well-known as [[Series/ParksAndRecreation Ron Swanson.]]

* CrackPairing: Would you believe that there is actually a very large portion of fanfiction writers that 'ship Will/Karen?

** In "Fagmalion" part four, Karen dated a handsome, intense maintenance man named Anton. About seven years later, his actor is providing the voice of a [[Disney/ThePrincessAndTheFrog handsome, less-than-intense prince-turned-frog.]]

** Another episode focuses on a straight camp.

* HarsherInHindsight: It was already hard for some to find Vince to be as good or likeable a person as the show insisted he was when he had multiple lines implying that he’d engaged in police brutality, but it’s especially difficult after the issue became one of the most widely recognised and debated problems of UsefulNotes/TheNewTens.

* MemeticMutation: A marinara fuck. [[labelnote: Explanation]]Uttered by Debra Messing in the bloopers for the first episode of the revived series.[[/labelnote]]

** Another episode focuses on a straight camp and treats it like something shocking and never done before.

* CrazyAwesome: Karen, full stop.

* HoYay: The two main guys on the show are both gay, so it's obvious they get this, bordering on actual ShipTease in several episodes.
* LesYay:

** There were a few rare barbs thrown at Grace by Karen (who usually called her boyish and flat-chested instead.) However, this showed clearly that this was deliberate. A few critics mentioned that the fat jokes thrown at Grace weren't as funny when Debra Messing was pregnant, showing that this was supposed to play off the ValuesDissonance of making fat jokes toward the slender [=McCormick=] and Messing, similar to the fat jokes made toward Vivian Vance during ''ILoveLucy.''

* FreudWasRight: Jack has the classic Freudian family pattern for homosexuality, but the trope's averted with Will: he's always had a good relationship with his father, and was close to his older brother Sam until he told Sam what he thought of Sam's fiancée. Will is, however, his mother's favourite. Will's gay friend Larry also appears to be very close to his mother. Elliot, on the other hand, also has the classic family pattern for homosexuality but he's straight as an arrow.

** In "Fagmalion" part four, Karen dated a handsome, intense maintenance man named Anton. About seven years later, his actor is providing the voice of a [[PrincessAndTheFrog handsome, less-than-intense prince-turned-frog.]]