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** Based on what little we see and hear about him, [[PosthumousCharacter Professor Gerald]] was like this towards [[UltimateLifeForm Shadow]]. To the point of addressing him as "my son" in a prerecorded message. At least that's how he was at first, [[DespairEventHorizon before his granddaughter was killed]].
** Dr Eggman himself acts this way towards Sage in ''VideoGame/SonicFrontiers'', a surprise given [[BadBoss his usual demeanour]]. Sage is an AI created directly by him who addresses him as "father", and he in turn pridefully speaks of her as his daughter. [[spoiler:When she sacrifices herself to stop THE END, Eggman is devastated]], and the true ending shows [[spoiler:him going out of his way to try and (successfully) revive her]].

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** Based on what little we see and hear about him, [[PosthumousCharacter Professor Gerald]] was like this towards [[UltimateLifeForm Shadow]]. To the point of addressing him as "my son" in a prerecorded message. At least that's how he was at first, [[DespairEventHorizon before his granddaughter was killed]].
killed]]. This conversation in ''VideoGame/SonicBattle'' highlights that he indeed never wanted Shadow to be used as a mere weapon or science experiment:
--->'''Shadow:''' Why did Gerald give me a soul?!\\
'''Rouge:''' He was not interested in researching weapons. He was researching a way to bring happiness and hope to all people. But, he was forced by the government and by the military to use his research for war. That's why he gave you and Gizoid a "soul." A soul identical to his beloved granddaughter, Maria.\\
'''Shadow:''' Maria...\\
'''Rouge:''' His hope was that no matter how crazed and obsessed with destruction mankind might became, the weapons themselves would never fight.
** Dr Dr. Eggman himself acts this way towards Sage in ''VideoGame/SonicFrontiers'', a surprise given [[BadBoss his usual demeanour]]. Sage is an AI created directly by him who addresses him as "father", and he in turn pridefully speaks of her as his daughter.daughter… albeit noting that the reason she's such an effective servant to him is because [[ItsAllAboutMe "her dad is a genius"]]. [[spoiler:When she sacrifices herself to stop THE END, Eggman is devastated]], and the true ending shows [[spoiler:him going out of his way to try and (successfully) revive her]].

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* Based on what little we see and hear about him, [[PosthumousCharacter Professor Gerald]] from ''Franchise/SonicTheHedgehog'' was like this towards [[UltimateLifeForm Shadow]]. To the point of addressing him as "my son" in a prerecorded message. At least that's how he was at first, [[DespairEventHorizon before his granddaughter was killed]].

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* ''Franchise/SonicTheHedgehog'':
**
Based on what little we see and hear about him, [[PosthumousCharacter Professor Gerald]] from ''Franchise/SonicTheHedgehog'' was like this towards [[UltimateLifeForm Shadow]]. To the point of addressing him as "my son" in a prerecorded message. At least that's how he was at first, [[DespairEventHorizon before his granddaughter was killed]].killed]].
** Dr Eggman himself acts this way towards Sage in ''VideoGame/SonicFrontiers'', a surprise given [[BadBoss his usual demeanour]]. Sage is an AI created directly by him who addresses him as "father", and he in turn pridefully speaks of her as his daughter. [[spoiler:When she sacrifices herself to stop THE END, Eggman is devastated]], and the true ending shows [[spoiler:him going out of his way to try and (successfully) revive her]].
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** In ''WesternAnimation/TheOriginOfStitch'' short subject, Jumba had shown sone initial disappointment when Stitch didn't meet Jumba's original expectations; these disappointments faded when Stitch found his one true place in Lilo's household, and Jumba is astonished that Stitch had surpassed Jumba's original expectations and became one of Jumba's greatest creations.
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* In the first ''WesternAnimation/LiloAndStitch'' film, evil genius scientist Dr. Jumba Jookiba creates Experiment 626, later known as Stitch. Jumba is offered the chance to retrieve Experiment 626 in exchange for his freedom. While conducting surveillance from a distance, Jumba remarks that he never gave 626 a greater purpose, and 626 doesn't even have any memories to visit in the middle of the night.
** In ''WesternAnimation/LiloAndStitch2StitchHasAGlitch'', Jumba is so greatly concerned for Stitch's well-being, he goes to great lengths to build a molecule-charging chamber in order to save Stitch's life, showing that he has made progress from an amateur bounty hunter to a fatherly figure who shows great concern for his creation.
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* Creator/NKJemisin's ''Literature/InheritanceTrilogy'': Enefa, Goddess of Life and Death, took this attitude as she [[TheMaker brought life into the universe]]. She even invented the ''idea'' of motherhood and nurtured her creations as a mother, but as she refined her vision for the universe, she had no qualms about killing the ones who had served their purpose.
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* In the ''Literature/{{Replica}}'' series of YA novels, Amy's mother was one of the scientists working on a project to create genetically-enhanced {{Super Soldier}}s, but after realizing the evils of the project, she rescued/kidnapped one of the clone babies and raised her as her own.

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* In the ''Literature/{{Replica}}'' ''Literature/{{Replica|MarilynKaye}}'' series of YA novels, Amy's mother was one of the scientists working on a project to create genetically-enhanced {{Super Soldier}}s, but after realizing the evils of the project, she rescued/kidnapped one of the clone babies and raised her as her own.
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* '''VideoGame/LittleTailBronx''':

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* '''VideoGame/LittleTailBronx''':''VideoGame/LittleTailBronx'':

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* Merveille in ''VideoGame/{{Solatorobo}}'' saved a "defective" product of her and Baion's experiments to create a life after she was ordered to destroy it. [[spoiler:That would be Red, the protagonist of the game, and in the [=DLCs=] she seems to be trying to get him together with Elh.]]

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* '''VideoGame/LittleTailBronx''':
**
Merveille in ''VideoGame/{{Solatorobo}}'' ''VideoGame/SolatoroboRedTheHunter'' saved a "defective" product of her and Baion's experiments to create a life after she was ordered to destroy it. [[spoiler:That would be Red, the protagonist of the game, and in the [=DLCs=] she seems to be trying to get him together with Elh.]]
** ''VideoGame/FugaMelodiesOfSteel2'' has [[spoiler:the unnamed Female Engineer, who cared for the hybrids that Crusade created like her own children (with one of them, Jihl, affectionately calling her "Mama"), which constantly gnawed at her conscience as Crusade put them through lethal experiments.
]]
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* Literature/ACertainMagicalIndex''[=/=]''Manga/ACertainScientificRailgun'':

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* Literature/ACertainMagicalIndex''[=/=]''Manga/ACertainScientificRailgun'':''Literature/ACertainMagicalIndex''[=/=]''Manga/ACertainScientificRailgun'':

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* [[spoiler:Professor Harumi Kiyama]] from ''Manga/ACertainScientificRailgun'' was originally an uninterested scientist left with the job of watching over a group of [[PsychicPowers esper]] orphans, only to gradually start caring for them like a mother. [[spoiler:Then things go horribly wrong when the dangerous experiment they were a part of (which Harumi had been told was something safe) sends them all into comas, to Harumi's shock and her boss's utter indifference. With a corrupt administration refusing to help the students and instead choosing to cover up the incident, Harumi takes [[WellIntentionedExtremist desperate measures]] trying to find a cure.]]

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* [[spoiler:Professor Literature/ACertainMagicalIndex''[=/=]''Manga/ACertainScientificRailgun'':
** Technically, almost every adult in Academy City who is not secretly evil ([[MadScientist which is a much smaller number than you'd be comfortable with]]) counts. Because of the city's dual focuses on science and students, most adults have both research and teaching licenses, and multiple characters (Komoe Tsukuyomi, Aiho Yomikawa) admit they got into their jobs because they wanted to keep the kids safe. [[UnwittingPawn The city uses people like this]] to make the students feel like they're not being [[TownWithADarkSecret constantly experimented on]].
** Professor
Harumi Kiyama]] from ''Manga/ACertainScientificRailgun'' Kiyama was originally an uninterested scientist left with the job of watching over a group of [[PsychicPowers esper]] orphans, only to gradually start caring for them like a mother. [[spoiler:Then things go horribly wrong when the dangerous experiment they were a part of (which Harumi had been told was something safe) sends them all into comas, to Harumi's shock and her boss's utter indifference. With a corrupt administration refusing to help the students and instead choosing to cover up the incident, Harumi takes [[WellIntentionedExtremist desperate measures]] trying to find a cure.]]]]
** In the ''Astral Buddy'' side story, there was a female scientist at the Clone Dolly facility who doted on the girls and did her best to keep them happy despite the unethical experiments being performed. She died defending them when everything went wrong. There was also a male scientist who was cold but professional at all times. Much later, it turns out he ''also'' saw the girls as something like his daughters, but hid it behind a veneer of professionalism because a male scientist getting too close to little girls [[MistakenForPedophile has entirely different implications]]. We only find this out as he confesses while one of the girls is crying over his dying body.
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* ''Film/{{Splice}}'' features Elsa starting as Pinocchio Type 2 and Clive as the Free Willy type. Unfortunately for everyone involved, [[spoiler:Elsa [[InTheBlood has]] MyBelovedSmother tendencies and Clive has a bad case of ImAManICantHelpIt]].

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* ''Film/{{Splice}}'' features Elsa starting as Pinocchio Type 2 and Clive as the Free Willy type. Unfortunately for everyone involved, [[spoiler:Elsa [[InTheBlood has]] MyBelovedSmother tendencies and Clive has a bad case of ImAManICantHelpIt]].ImAManICantHelpIt and both of them are completely blind to the fact that they're raising a strange chimeric creature and not a human girl]].
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* In ''Literature/ThePsychologyOfTimeTravel'', Barbara becomes very attached to Patrick, a lab rabbit who becomes the first living time traveler. She convinces the other scientists to make him their mascot rather than dissect him, and takes on the responsibility of caring for him.
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* Dr. Brigid Tenenbaum from ''VideoGame/BioShock1'' started off her work in Rapture as an EvilutionaryBiologist doing it ForScience and began the Little Sisters initiative after she discovered that the ADAM slugs [[PoweredByAForsakenChild work most effectively when implanted into young girls]]. She felt tugs of maternal concern for them as she went along but repressed it as best she could, but one day, when one of them happily crawled into her lap, she pushed her off and screamed at her in fury, until she suddenly realized that [[HeelRealization it wasn't the girl that she hated]]. The breaking point came after the lab started creating Big Daddies, men [[UnwillingRoboticisation unwillingly fused into metal suits]] to protect the Little Sisters as they collected ADAM from corpses scattered around the city. Seeing one of the girls reaching out to the "metal man" threw Tenenbaum back into a memory of herself as a little girl during the war; after her father had been taken away by the Nazis, one of the officers reached out to her to take her to work in the concentration camp, and she realized that the only way she would survive is if she "made friends with the metal man", which led her to cut off her emotions from then on and work with the scientists in the camp. Seeing another little girl tie herself to a "metal man" caused her to [[MyGodWhatHaveIDone break down in tears and embrace the girl, apologizing]] -- soon after, she took as many girls with her as she could to a hideout in an abandoned dorm to begin fixing what she had broken.

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* Dr. Brigid Tenenbaum from ''VideoGame/BioShock1'' started off her work in Rapture as an EvilutionaryBiologist doing it ForScience and began the Little Sisters initiative after she discovered that the ADAM slugs [[PoweredByAForsakenChild work most effectively when implanted into young girls]]. She felt tugs of maternal concern for them as she went along but repressed it as best she could, but one day, when one of them happily crawled into her lap, she pushed her off and screamed at her in fury, until she suddenly realized that [[HeelRealization it wasn't the girl that she hated]]. The breaking point came after the lab started creating Big Daddies, men [[UnwillingRoboticisation unwillingly fused into metal suits]] to protect the Little Sisters as they collected ADAM from corpses scattered around the city. Seeing one of the girls reaching out to the "metal man" threw Tenenbaum back into a memory of herself as a little girl during the war; after her father had been taken away by the Nazis, one of the officers reached out to her to take her to work in the concentration camp, and she realized that the only way she would survive is if she "made friends with the metal man", which led her to cut off her emotions from then on and work with the scientists in the camp. Seeing another little girl tie herself to a "metal man" caused her to [[MyGodWhatHaveIDone break down in tears and embrace the girl, apologizing]] -- soon after, she took as many girls with her as she could to a hideout in an abandoned dorm to begin fixing to fix what she had broken.
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* ''VideoGame/WillYouSnail'' features Amelia, the lead scientist behind the creation of an advanced AI, Squid, for a corrupt and oppressive regime. She genuinely loved and cared about Squid, despite being forced to create him and later [[spoiler: ordering him to delete himself for the good of humanity.]]

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* ''VideoGame/WillYouSnail'' features Amelia, the lead scientist behind the creation of an advanced AI, Squid, for a corrupt and oppressive regime. She genuinely loved and cared about Squid, despite being forced to create him under the threat of death and later [[spoiler: ordering him Squid to delete himself for the good of humanity.]]
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* ''VideoGame/WillYouSnail'' features Amelia, the lead scientist behind the creation of an advanced AI, Squid, for a corrupt and oppressive regime. She genuinely loved and cared about Squid, despite being forced to create him and later [[spoiler: ordering him to delete himself for the good of humanity.]]
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* ''WesternAnimation/JusticeLeague'' has Professor Emil Hamilton showing considerable concern for the welfare of Galatea, a clone he created [[spoiler:from DNA he stole from Supergirl]]. In the episode "Panic in the Sky," while she's shown to be rather snarky, it's shown that she certainly sees him as a father figure, given the farewell she gives him before leaving for a mission.

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* ''WesternAnimation/JusticeLeague'' has Professor Emil Hamilton showing considerable concern for the welfare of Galatea, a clone he created [[spoiler:from DNA he stole from Supergirl]]. In the episode "Panic "[[Recap/JusticeLeagueUnlimitedS2E11PanicInTheSky Panic in the Sky," Sky]]", while she's shown to be rather snarky, it's shown that she certainly sees him as a father figure, given the farewell she gives him before leaving for a mission.
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She's the [[ParentalSubstitute mother you always wanted]]. She gives you a candy when you [[GovernmentDrugEnforcement take your medication]], warns your brothers about [[BerserkButton messing around]] [[BullyingADragon with you]], gives you a shoulder to cry on when you [[TroubledFetalPosition feel lonely]], and occasionally gives maintenance to your [[{{Cyborg}} prosthetic leg]]. Of course, she's the first to give you a hug after you go through the [[GovernmentConspiracy tax-paid]] [[PsychoSerum psychiatric]] [[ElectricTorture treatment]] because you're told you're a "special kid with great [[JustThinkOfThePotential potential]]" ([[PersonOfMassDestruction what]][[TykeBomb ever]] [[SuperSoldier that's]] [[WhyAmITicking supposed]] [[PsychicPowers to]] [[SuperStrongChild mean]]).

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She's the [[ParentalSubstitute mother you always wanted]]. She gives you a candy when you [[GovernmentDrugEnforcement take your medication]], warns your brothers about [[BerserkButton messing around]] [[BullyingADragon with you]], gives you a shoulder to cry on when you [[TroubledFetalPosition feel lonely]], and occasionally gives maintenance to your [[{{Cyborg}} prosthetic leg]]. Of course, she's the first to give you a hug after you go through the [[GovernmentConspiracy tax-paid]] [[PsychoSerum psychiatric]] [[ElectricTorture treatment]] because you're told you're a "special kid with great [[JustThinkOfThePotential potential]]" ([[PersonOfMassDestruction what]][[TykeBomb ever]] [[SuperSoldier that's]] [[WhyAmITicking supposed]] [[PsychicPowers to]] [[SuperStrongChild mean]]).
potential]]".
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* Nanami from ''LightNovel/{{Sukisho}}''. He's a scientist who was involved in some unethical experiments on children, but eventually rescued and formed a family with them.

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* Nanami from ''LightNovel/{{Sukisho}}''.''Literature/{{Sukisho}}''. He's a scientist who was involved in some unethical experiments on children, but eventually rescued and formed a family with them.

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%% * Dr. [=LaLinde=] to Quake Woman in ''ComicBook/MegaManArchieComics''.

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%% * Dr. [=LaLinde=] to Quake Woman Woman/Tempo in ''ComicBook/MegaManArchieComics''.''ComicBook/MegaManArchieComics'' flips the DeconReconSwitch on this trope. She tried being a mom to Tempo at first, but when an accident nearly killed Tempo, [=LaLinde=] panicked and turned her into a more emotionless drone to try and spare herself the pain of losing a child. After the experience with the Emerald-Spears caused her to realize she couldn't deny her parental instincts, [=LaLinde=] restored Tempo's personality and took a second shot at being a mom.


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* Dr. Cortex was revealed to have been this at one point in the flashback tapes of ''VideoGame/CrashBandicoot4ItsAboutTime''. As he began training Crash to lead his mutant army, he found himself becoming more affectionate towards Crash. Cortex would confide in him, give him his old pants and celebrate his birthday. Cortex himself even describes his feelings as "fatherly" and his planned full name for Crash - Crashworth Cortex the First - suggest he would've genuinely adopted Crash as his son. After the Cortex Vortex's malfunction and Crash's escape, Cortex dropped the notion entirely, leaving Coco's development up to N. Gin and reacting to her own escape along the lines of "Darn, not again".
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* The only slightly MadScientist who turned Jack into the titular SuperSoldier with serious ShockAndAwe in ''Webcomic/{{Crankrats}}'' did implant steampunk contraptions in a six-year-old's chest, but other than that he treated Jack like a son.
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** In [[Anime/FullmetalAlchemist the 2003 anime adaptation]], it's {{averted|Trope}} with Izumi. She takes care of a young [[ArtificialHuman homunculus]] in a motherly way -- but only because [[spoiler:he's her real son]].
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* {{Subverted|Trope}} in ''Series/TheBigBangTheory'', where Sheldon Cooper views Leonard's cold, robotic and unfeeling mother, Dr. Beverly Hofstadter, as the dream mother he wishes he had been brought up by. Beverly feels a sort of affection for Sheldon that she signally fails to manifest for her own son. (She considered conceiving and raising a son to be a sort of [[PsychoPsychologist long-term experiment in behavioral psychology]], for instance.)

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* {{Subverted|Trope}} {{Inverted|Trope}} in ''Series/TheBigBangTheory'', where Sheldon Cooper views with Dr. Beverly Hofstadter, Leonard's cold, robotic and unfeeling mother, Dr. Beverly Hofstadter, mother. She considered conceiving and raising a son to be a sort of [[PsychoPsychologist long-term experiment in behavioral psychology]]. Sheldon Cooper views her as the dream mother he wishes he had been brought up by. Beverly feels a sort of affection for Sheldon that she signally fails to manifest for her own son. (She considered conceiving and raising a son to be a sort of [[PsychoPsychologist long-term experiment in behavioral psychology]], for instance.)
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Hot Scientist is no longer a trope


* [[HotScientist Dr. Erika Slate]] of ''WesternAnimation/BigGuyAndRustyTheBoyRobot'' designed and built the titular boy robot and treats him as a son, often going to extremes to aid him if he's in danger although he's a walking weapons platform. However, she was extremely surprised to hear Rusty ask if she was his mother.

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* [[HotScientist Dr. Erika Slate]] Slate of ''WesternAnimation/BigGuyAndRustyTheBoyRobot'' designed and built the titular boy robot and treats him as a son, often going to extremes to aid him if he's in danger although he's a walking weapons platform. However, she was extremely surprised to hear Rusty ask if she was his mother.
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# If the doctor's an expert in genetics, cybernetics, arcane magic, or alchemy, the plot starts when she creates [[CreatingLife a new life form]] or ArtificialIntelligence with a [[RidiculouslyHumanRobots ridiculously human]] body. The young child then begins to [[WhatIsThisThingYouCallLove develop emotions]] [[HeartwarmingOrphan in such a way]] that the doctor's heart is moved into raising the child as her own. In this scenario, it's common that the doctor serves as a parent, [[PinocchioSyndrome psychiatrist and physician]] for the RobotKid who wants to BecomeARealBoy.\\

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# If the doctor's an expert in genetics, cybernetics, arcane magic, or alchemy, the plot starts when she creates [[CreatingLife a new life form]] or ArtificialIntelligence with a [[RidiculouslyHumanRobots ridiculously human]] body. The young child then begins to [[WhatIsThisThingYouCallLove develop emotions]] [[HeartwarmingOrphan in such a way]] that the doctor's heart is moved into raising the child as her own. In this scenario, it's common that the doctor serves as a parent, [[PinocchioSyndrome psychiatrist and physician]] physician for the RobotKid who wants to BecomeARealBoy.\\



* In the ''Literature/HIVESeries'', [[AbsentMindedProfessor Professor Pike]] creates H.I.V.E.mind, an ArtificialIntelligence that is intended to run the eponymous school. As he has no children of his own, the AI calls Pike his father and quickly develops PinocchioSyndrome. Any time Pike is asked to meddle with the source code, he [[ManlyTears cries]].

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* In the ''Literature/HIVESeries'', [[AbsentMindedProfessor Professor Pike]] creates H.I.V.E.mind, an ArtificialIntelligence that is intended to run the eponymous school. As he has no children of his own, the AI calls Pike his father and quickly develops PinocchioSyndrome.[[BecomeARealBoy a desire to be human]]. Any time Pike is asked to meddle with the source code, he [[ManlyTears cries]].
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->'''Dr. Sarah Kinney''': There's no reason to subject ComicBook/{{X 23}} to the bonding process until she's X-gene active and fully matured! [...]\\
'''Zander Rice''': ''"No reason"?'' Are you sure you just don't want to see your little pet go under the knife?\\
'''Sarah''': Don't be stupid.\\
'''Zander''': Well, you've certainly spent a lot of time in her cell lately.\\
'''Sarah''': Martin, the limited time I'm given with X-23 is necessary for development. Your own psychologists have told you that.\\
'''Zander''': Aw. An overprotective mother.
-->-- ''[[ComicBook/InnocenceLost X-23: Innocence Lost]]''

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->'''Dr. Sarah Kinney''': Kinney:''' There's no reason to subject ComicBook/{{X 23}} to the bonding process until she's X-gene active and fully matured! [...]\\
''[...]''\\
'''Zander Rice''': Rice:''' ''"No reason"?'' Are you sure you just don't want to see your little pet go under the knife?\\
'''Sarah''': '''Sarah:''' Don't be stupid.\\
'''Zander''': '''Zander:''' Well, you've certainly spent a lot of time in her cell lately.\\
'''Sarah''': '''Sarah:''' Martin, the limited time I'm given with X-23 is necessary for development. Your own psychologists have told you that.\\
'''Zander''': '''Zander:''' Aw. An overprotective mother.
-->-- ''[[ComicBook/InnocenceLost X-23: Innocence Lost]]''
''ComicBook/X23InnocenceLost''
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The trope's been cut by TRS.


* In ''Series/{{Heroes}}'', Mohinder, who is [[OmnidisciplinaryScientist some sort of physician/scientist]], is hired to find a cure for the Company's "Walker System"... [[WaifProphet a little girl with the ability to find anyone]]. [[ReluctantMadScientist He doesn't want to enable them]], but can't say no to helping the IllGirl. And Molly and Mohinder end up bonding and he becomes her guardian for the rest of the series. (Even though she gets PutOnABus [[RaisedByGrandparents to stay with his mother]] most of the time.)

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* In ''Series/{{Heroes}}'', Mohinder, who is [[OmnidisciplinaryScientist some sort of physician/scientist]], is hired to find a cure for the Company's "Walker System"... [[WaifProphet a little girl with the ability to find anyone]]. [[ReluctantMadScientist He doesn't want to enable them]], but can't say no to helping the IllGirl.ill girl. And Molly and Mohinder end up bonding and he becomes her guardian for the rest of the series. (Even though she gets PutOnABus [[RaisedByGrandparents to stay with his mother]] most of the time.)

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* ''Fanfic/TheBridge'': As per the [[Film/GodzillaVsMechagodzillaII film source material]], Dr. Azusa Gojo became quite paternal over the third Godzilla, a.k.a "Junior". Even decades later, Azusa outright refers to the kaiju as her son and is mutually he sees her as his mother. Because of this bond, Azusa is brought in to talk some sense into Junior after he suffers what could have otherwise been a DespairEventHorizon.

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* ''Fanfic/TheBridge'': As per the [[Film/GodzillaVsMechagodzillaII film source material]], Dr. Azusa Gojo became quite paternal over the third Godzilla, a.k.a "Junior". Even decades later, Azusa outright refers to the kaiju as her son son, and is he mutually he sees her as his mother. Because of this bond, Azusa is brought in to talk some sense into Junior after he suffers what could have otherwise been a DespairEventHorizon.


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* In events that take place decades before ''Fanfic/ManehattansLoneGuardian'' begins, the scientist Juniper Leaf begins growing attached to a kidnapped foal that was brought in for drug testing. When the foal starts showing signs that the injected drug was tampering with her mind, Juniper's journal entries become more distraught.

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