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* One Wolverine story involves him helping out a caveman who was one of three abducted and experimented on by a [[{{Ultra terrestrial}} Deviant]] scientist attempting to discover a way to extend Deviant lifespans. The process worked, but he never gets to see it as he dies when their civilization is destroyed just after he finishes the procedure. That was thousands of years before recorded human history and the caveman is still perfectly well.
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* In the ''Videogame/{{Fallout}}'' series, radiation under very specific conditions [[note]](by and large seems to be long-term exposure to high levels of background radiation)[[/note]] can render a person effectively immortal, turning them into a 'ghoul'. Ghouls do not age and even heal from radiation, but lose most of their skin and hair as it flakes off in big chunks, suffer the long term effects of age leading to severe cataracts and arthritis, and becoming infertile. However, those exposed to too much radiation during ghoulification - but not enough to outright kill them - lose their mind and become 'feral', essentially mindless zombies. Ghouls who receive even more radiation can become Glowing Ones, ghouls that have a SicklyGreenGlow and can erupt in a burst of radiation to harm and heal. While most Glowing One ghouls are feral, one Jason [[MeaningfulName Bright]] is a Glowing One who hasn't become feral and leads a cult in a rocket facility in [[VideoGame/FalloutNewVegas Henderson]]. In ''Videogame/{{Fallout 4}}'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.

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* In the ''Videogame/{{Fallout}}'' series, radiation under very specific conditions [[note]](by and large seems to be long-term exposure to high levels of background radiation)[[/note]] can render a person effectively immortal, turning them into a 'ghoul'. 'ghoul.' Ghouls do not age and even heal from radiation, but lose most of their skin and hair as it flakes off in big chunks, suffer the long term effects of age leading to severe cataracts and arthritis, and becoming infertile. However, those exposed to too much radiation during ghoulification - but not enough to outright kill them - lose their mind and become 'feral', essentially mindless zombies. Ghouls who receive even more radiation can become Glowing Ones, ghouls that have a SicklyGreenGlow and can erupt in a burst of radiation to harm and heal. While most Glowing One ghouls are feral, one Jason [[MeaningfulName Bright]] is a Glowing One who hasn't become feral and leads a cult in a rocket facility in [[VideoGame/FalloutNewVegas Henderson]]. In ''Videogame/{{Fallout 4}}'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.



* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us", which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain. The species from whose computer equipment carbosilicate amorphs has evolved already made themselves immortal and ran into several layers of problems. Still, there's a few remaining individuals alive and sane after their twelve million Terran years, [[http://www.schlockmercenary.com/2007-07-14 "give or take a little bit."]]

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* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us", Laz'r'us," which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain. The species from whose computer equipment carbosilicate amorphs has evolved already made themselves immortal and ran into several layers of problems. Still, there's a few remaining individuals alive and sane after their twelve million Terran years, [[http://www.schlockmercenary.com/2007-07-14 "give or take a little bit."]]

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* In ''VideoGame/MoonChronicles'' an alien installation is discovered on the moon. Further investigation shows that the aliens have been harvesting humans for centuries in order to make a substance that restores health and prolongs life.



* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us", which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain. The species from whose computer equipment carbosilicate amorphs has evolved already made themselves immortal and ran into several layers of problems. Still, there's a few remaining individuals alive and sane after their twelve million Terran years, "[[http://www.schlockmercenary.com/2007-07-14 give or take a little bit]]".

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* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us", which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain. The species from whose computer equipment carbosilicate amorphs has evolved already made themselves immortal and ran into several layers of problems. Still, there's a few remaining individuals alive and sane after their twelve million Terran years, "[[http://www.[[http://www.schlockmercenary.com/2007-07-14 give "give or take a little bit]]".bit."]]
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** The sarcophagus can extend the life of a human without a [[PuppeteerParasite Goa'uld]] for 700 years or so, hosts for millennia. Unfortunately it makes the user megalomaniacal. [[ImmortalityImmorality Because reasons.]]

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** The sarcophagus can extend the life of a human without a [[PuppeteerParasite Goa'uld]] for 700 years or so, hosts and a human that is a host to Goa'uld for millennia. Unfortunately it makes the user megalomaniacal. [[ImmortalityImmorality Because reasons.]]
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-->-- '''CEO Nwabudike Morgan, [=MorganLink=] [=3DVision=] Live Interview''', "Longevity Vaccine", ''VideoGame/SidMeiersAlphaCentauri''

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-->-- '''CEO Nwabudike Morgan, [=MorganLink=] [=3DVision=] Live Interview''', "Longevity Vaccine", Vaccine," ''VideoGame/SidMeiersAlphaCentauri''



* In John Norman's ''Literature/{{Gor}}'' novels, the Caste of Physicians developed a treatment called the Stabilization Serums, which allowed the recipient to live for hundreds of years [[note]]in 'Marauders of Gor', Tarl meets someone who is almost certainly the legendary founder of Torvaldsland, which would make him about 1000 years old[[/note]]. The Priest-Kings, the PhysicalGods of the setting, have a similar treatment, the oldest being about 5,000,000 years old.

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* In John Norman's ''Literature/{{Gor}}'' novels, the Caste of Physicians developed a treatment called the Stabilization Serums, which allowed the recipient to live for hundreds of years [[note]]in years.[[note]]In 'Marauders of Gor', Tarl meets someone who is almost certainly the legendary founder of Torvaldsland, which would make him about 1000 years old[[/note]]. old.[[/note]] The Priest-Kings, the PhysicalGods of the setting, have a similar treatment, the oldest being about 5,000,000 years old.
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** There's also an event where you find a tree floating in space with sap that can extend your leaders' lifespans, or be distributed to the whole population for a boost in morale.

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** There's also an event where [[ShoutOut you find a a]] [Film/TheFountain tree floating in space space]] with sap that can extend your leaders' lifespans, or be distributed to the whole population for a boost in morale.
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* In ''WesternAnimation/{{Gargoyles}}'', the Illuminati provides life extending drugs to its senior members such as Mace Malone, who is in remarkably good health for a man in his nineties. When Matt Bluestone remarks on this, Mace wrly responds that [[SignedUpForTheDental Matt should see their dental plan]], flashing a smile full of perfect white, even natural teeth.

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* In ''WesternAnimation/{{Gargoyles}}'', the Illuminati provides life extending drugs to its senior members such as Mace Malone, who is in remarkably good health for a man in his nineties. When Matt Bluestone remarks on this, Mace wrly responds that [[SignedUpForTheDental Matt should see their dental plan]], flashing a smile full of perfect white, even even, natural teeth.

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* In ''WesternAnimation/{{Gargoyles}}'', the Illuminati provides life extending drugs to its senior members such as Mace Malone, who is in remarkably good health for a man in his nineties. When Matt Bluestone remarks on this, Mace wrly responds that [[SignedUpForTheDental Matt should see their dental plan]], flashing a smile full of perfect white, even natural teeth.
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* In Creator/DavidDrake's ''Literature/RanksOfBronze'' the alien trade guild that purchases [[LostRomanLegion Crassus' legions]] as slave-warriors give them longevity treatments to keep them fighting for roughly two thousand years.



* ''VideoGame/{{Stellaris}}'' has a variety of technologies that add extra years to your Leaders' life expectancies, it's also possible to use [[LegoGenetics gene tailoring]] to add the [[LongLived Enduring (+30 years) or Venerable (+90)]] traits to one or more of your species.

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* ''VideoGame/{{Stellaris}}'' has a variety of technologies that add extra years to your Leaders' life expectancies, it's also possible to use [[LegoGenetics gene tailoring]] to add the [[LongLived Enduring (+30 (+20 years) or Venerable (+90)]] (+80)]] traits to one or more of your species.
** There's also an event where you find a tree floating in space with sap that can extend your leaders' lifespans, or be distributed to the whole population for a boost in morale.
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** The Bene Gesserit can also alter their own body chemistry to stop aging altogether if they choose to. They deliberately don't choose this because people would notice the resulting ageless women and conflict would result. That Alia has broken the taboo against it in ''Children of Dune'' is one of many things her mother Jessica takes issue with.
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** ''A World Out of Time'' has an immortality treatment for adults that involves removing impurities from the body.

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** ''A World Out of Time'' ''Literature/AWorldOutOfTime'' has an immortality treatment for adults that involves removing impurities from the body.
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* From Creator/LarryNiven's ''Literature/KnownSpace'' stories:
** Boosterspice (a drug derived from genetically engineered ragweed) can tremendously extend the human lifespan.

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* From Creator/LarryNiven's stories:
** In the
''Literature/KnownSpace'' stories:
**
setting, Boosterspice (a drug derived from genetically engineered ragweed) can tremendously extend the human lifespan.
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-->'''[=-=][=-=] CEO Nwabudike Morgan, [=MorganLink=] [=3DVision=] Live Interview''', "Longevity Vaccine", ''VideoGame/SidMeiersAlphaCentauri''

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-->'''[=-=][=-=] CEO -->-- '''CEO Nwabudike Morgan, [=MorganLink=] [=3DVision=] Live Interview''', "Longevity Vaccine", ''VideoGame/SidMeiersAlphaCentauri''



* In ''Turnabout'' by Margaret Peterson Haddix, the government is working on a top-secret experiment in 2000 to reverse the aging process. And it works - the main characters, who were extremely elderly and would have died before long, are given the chance to grow young again. Unfortunately, they haven't figured out a working way to ''stop'' the un-aging.

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* In ''Turnabout'' by Margaret Peterson Haddix, Creator/MargaretPetersonHaddix, the government is working on a top-secret experiment in 2000 to reverse the aging process. And it works - -- the main characters, who were extremely elderly and would have died before long, are given the chance to grow young again. Unfortunately, they haven't figured out a working way to ''stop'' the un-aging.
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* In the ''Videogame/{{Fallout}}'' series, radiation under very specific conditions [[note]](by and large seems to be long-term exposure to high levels of background radiation)[[/note]] can render a person effectively immortal, turning them into a 'ghoul'. Ghouls do not age and even heal from radiation, but lose most of their skin and hair as it flakes off in big chunks, suffer the long term effects of age leading to severe cataracts and arthritis, and becoming infertile. However, those exposed to too much radiation during ghoulification - but not enough to outright kill them - lose their mind and become 'feral', essentially mindless zombies. Ghouls who receive even more radiation can become Glowing Ones, ghouls that glow a SicklyGreen and can erupt in a burst of radiation to harm and heal. While most Glowing One ghouls are feral, one Jason [[MeaningfulName Bright]] is a Glowing One who hasn't become feral and leads a cult in a rocket facility in [[VideoGame/FalloutNewVegas Henderson]]. In ''Videogame/{{Fallout 4}}'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.

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* In the ''Videogame/{{Fallout}}'' series, radiation under very specific conditions [[note]](by and large seems to be long-term exposure to high levels of background radiation)[[/note]] can render a person effectively immortal, turning them into a 'ghoul'. Ghouls do not age and even heal from radiation, but lose most of their skin and hair as it flakes off in big chunks, suffer the long term effects of age leading to severe cataracts and arthritis, and becoming infertile. However, those exposed to too much radiation during ghoulification - but not enough to outright kill them - lose their mind and become 'feral', essentially mindless zombies. Ghouls who receive even more radiation can become Glowing Ones, ghouls that glow have a SicklyGreen SicklyGreenGlow and can erupt in a burst of radiation to harm and heal. While most Glowing One ghouls are feral, one Jason [[MeaningfulName Bright]] is a Glowing One who hasn't become feral and leads a cult in a rocket facility in [[VideoGame/FalloutNewVegas Henderson]]. In ''Videogame/{{Fallout 4}}'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.
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** There is a secret project called 'The Longevity Vaccine' and another called 'Clinical Immortality'.

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** There is a secret project called 'The Longevity Vaccine' and another called 'Clinical Immortality'. The former is a simple injection, the latter involves removing the [[BrainInAJar brain, spine, and eyes and placing them in a glass machine]] giving the user [[ExactWords Clinical Immortality]].



* In the ''Videogame/{{Fallout}}'' series, radiation under very specific conditions can render a person effectively immortal, turning them into a 'ghoul'. Ghouls do not age, but lose most of their skin and hair, and become infertile. However, those exposed to too much radiation during ghoulification - but not enough to outright kill them - lose their mind and become 'feral', essentially mindless zombies. In ''Videogame/{{Fallout 4}}'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.
** While the Super Mutants altered by the Forced Evolution Virus in ''VideoGame/{{Fallout 1}}'' are still around and at full fighting strength over a century later.

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* In the ''Videogame/{{Fallout}}'' series, radiation under very specific conditions [[note]](by and large seems to be long-term exposure to high levels of background radiation)[[/note]] can render a person effectively immortal, turning them into a 'ghoul'. Ghouls do not age, age and even heal from radiation, but lose most of their skin and hair, hair as it flakes off in big chunks, suffer the long term effects of age leading to severe cataracts and become arthritis, and becoming infertile. However, those exposed to too much radiation during ghoulification - but not enough to outright kill them - lose their mind and become 'feral', essentially mindless zombies. Ghouls who receive even more radiation can become Glowing Ones, ghouls that glow a SicklyGreen and can erupt in a burst of radiation to harm and heal. While most Glowing One ghouls are feral, one Jason [[MeaningfulName Bright]] is a Glowing One who hasn't become feral and leads a cult in a rocket facility in [[VideoGame/FalloutNewVegas Henderson]]. In ''Videogame/{{Fallout 4}}'', Eddie Winters, a Pre-War crime lord, underwent an experimental radiation regime months before the Great War. He's still kicking 220 years later. Other people got ghoulified the hard way -- gamma radiation from nuclear bombs.
** While the Super Mutants altered by the Forced Evolution Virus in ''VideoGame/{{Fallout 1}}'' are still around and at full fighting strength over a century later. Super Mutant bodies have increased healing, durability, and strength but are infertile due to said healing [[note]](as Marcus says, it takes a few years to "get the juices flowing", so it doesn't mean they are castrated[[/note]] and lack secondary sexual characteristics. Of course, becoming a Super Mutant isn't easy, painless, or safe. It involves being dipped in a massive vat of FEV or having direct injections to force the change and only humans from Vaults have the minimum damage to their DNA to allow themselves to keep their intelligence afterwards before long-term Stealth Boy usage rots their minds. The East Coast Mutants in the [[Videogame/Fallout3 Capital]] and [[Videogame/Fallout4 Boston]] Wastelands are the result of leftover FEV found in Vault 87 in the former and used by the Institute in the latter.
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* The Lazarus Pits used by ComicBook/RasAlGhul rejuvenate him every century or so.

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* The Lazarus Pits used by ComicBook/RasAlGhul rejuvenate him every century or so. Various adaptations depict the process as having diminishing returns, putting more pressure on him to find a "worthy heir" before it stops working and / or he goes totally feral.
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-> ''"I plan to live forever of course, but barring that, I'd settle for a couple thousand years. Even five hundred would be pretty nice."''
-->-- '''CEO Nwabudike Morgan - [=MorganLink=] [=3DVision=] Interview''', ''VideoGame/SidMeiersAlphaCentauri''

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-> ''"I ->''"I plan to live forever forever, of course, but barring that, that I'd settle for a couple thousand years. Even five hundred would be pretty nice."''
-->-- '''CEO -->'''[=-=][=-=] CEO Nwabudike Morgan - Morgan, [=MorganLink=] [=3DVision=] Live Interview''', "Longevity Vaccine", ''VideoGame/SidMeiersAlphaCentauri''


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* In ''Literature/{{Neogicia}}'', this is one of the applications of the Empire's BioAugmentation technology. The ruling family keeps it mostly for itself. A character suspects they do this because too many people with access to this treatment may cause the ImmortalProcreationClause to kick in and it may not make everyone happy.
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* ''ComicBook/JudgeDredd'': Aging has been slowed down quite a bit after most diseases have been eradicated and anti-aging drugs and skin grafting have become more advanced. Judge Dredd for instance is chronologically in his 70s, but still looks like a 40-something.

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* Longevity treatments exist in the ''MutantChronicles'' setting, but between the astronomic expense, the invasive surgery and the extremely strict regimen of diet and exercise required for the treatment to be effective, very few people bother.

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* Longevity treatments exist in the ''MutantChronicles'' ''TabletopGame/MutantChronicles'' setting, but between the astronomic expense, the invasive surgery and the extremely strict regimen of diet and exercise required for the treatment to be effective, very few people bother.

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* The Betans of the ''Literature/VorkosiganSaga'' allegedly have one, which people assume is the reason that Admiral Naismith commands a mercenary fleet while appearing to be in his early twenties. In truth, there is no such treatment, and Admiral Naismith really is in his early twenties. The Jacksonians have a highly unethical treatment in which the brain of a wealthy client is transferred into the body of a younger clone. Mark Vorkosigan has made it his life's work to eliminate that practice, and as of the chronologically latest book was about to begin testing of a treatment that could potentially revert someone from 'old' to 'middle aged'.

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* ''Literature/VorkosiganSaga'':
**
The Betans of the ''Literature/VorkosiganSaga'' allegedly a rumored to have one, which people assume is the reason that Admiral Naismith commands a mercenary fleet while appearing to be in his early twenties. In truth, there is no such treatment, and Admiral Naismith really is in his early twenties. twenties.
**
The Jacksonians have a highly unethical treatment in which the brain of a wealthy client is transferred into the body of a younger clone. Mark Vorkosigan has made it his life's work to eliminate that practice, and as of the chronologically latest book was about to begin testing of a treatment that could potentially revert someone from 'old' to 'middle aged'.
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* ''VideoGame/{{Stellaris}}'' has a variety of technologies that add extra years to your Leaders' life expectancies, it's also possible to use [[LegoGenetics gene tailoring]] to add the [[LongLivedSpecies Enduring (+30 years) or Venerable (+90)]] traits to one or more of your species.

to:

* ''VideoGame/{{Stellaris}}'' has a variety of technologies that add extra years to your Leaders' life expectancies, it's also possible to use [[LegoGenetics gene tailoring]] to add the [[LongLivedSpecies [[LongLived Enduring (+30 years) or Venerable (+90)]] traits to one or more of your species.
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to:

* ''VideoGame/{{Stellaris}}'' has a variety of technologies that add extra years to your Leaders' life expectancies, it's also possible to use [[LegoGenetics gene tailoring]] to add the [[LongLivedSpecies Enduring (+30 years) or Venerable (+90)]] traits to one or more of your species.

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* The setting of ''Literature/ThePrincesOfTheAir'' has a longevity treatment which is only available to the rich and powerful. When we first meet the protagonist he's running a con where the bait is illicit access to the longevity treatment.
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* In ''TabletopGame/HcSvntDracones'' the Mega Corps don't want immortal customers, even though they have the technology for it. Pulse and Progenitus do offer "graceful aging" treatments that keep a client healthy and active through their nineties, but include a "termination date" somewhere around age 100. Still, some very valuable employees manage to secure long-term contracts that include body replacement at the end of their natural lifespan.
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* In ''Series/TheTwilightZone'' episode "The Trade-Ins" an elderly couple go to a clinic that can give them new, younger bodies. But, they only have enough money for one of them.

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* In ''Series/TheTwilightZone'' ''Series/TheTwilightZone1959'' episode "The Trade-Ins" Trade-Ins", an elderly couple go to a clinic that can give them new, younger bodies. But, they only have enough money for one of them.
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* In ''Literature/ThisImmortal'', there is the so-called S-S treatment that's never specified but is said to be able to prolong a human's lifespan to 150 years and above.
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* In Creator/StephenBaxter's ''Literature/XeeleeSequence'' novels, humanity invents Anti-Senescence technology which repairs genetic damage due to age via nanobots. The treatment has a 99% success rate, though treatment failures typically end with a terminal illness. Lifespan with AS treatments theoretically has no upper limit, though in practice the treatments begin to break down at 400-500 years; in the novella ''Mayflower II'', after 40,000 years of flight the captain of a GenerationShip is little more than a BrainInAJar, with his desiccated body permanently wired into a life support chair.
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* A less sci-fi example in ''Series/{{Torchwood}}'' with Angelo Colasanto. After witnessing Jack's immortality in 1927, he starts researching ways of prolonging his life, which appear to be grounded in RealLife techniques (e.g. going vegetarian, slowing down one's metabolism), and manages to live until 2011.

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