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* Longevity treatments exist in the ''MutantChronicles'' setting, but are hideously expensive (starting at 1000000 crowns/year, when a laborer is lucky to have a 40000 crown annual salary), require invasive surgery and have to be combined with an extremely strict regimen of diet and exercise to be effective. Very few people find it worthwhile.
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* In John Norman's ''Literature/{{Gor}}'' novels, the Caste of Physicians developed a treatment called the Stabilization Serums, which allowed the recipient to live for hundreds of years. The Priest-Kings, the PhysicalGods of the setting, have a similar treatment, the oldest being about 5,000,000 years old.

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* In John Norman's ''Literature/{{Gor}}'' novels, the Caste of Physicians developed a treatment called the Stabilization Serums, which allowed the recipient to live for hundreds of years.years [[note]]in 'Marauders of Gor', Tarl meets someone who is almost certainly the legendary founder of Torvaldsland, which would make him about 1000 years old[[/note]]. The Priest-Kings, the PhysicalGods of the setting, have a similar treatment, the oldest being about 5,000,000 years old.
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* The Lazarus Pits used by [[Franchise/{{Batman}} Ra's al Ghul]] rejuvenate him every century or so.

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* The Lazarus Pits used by [[Franchise/{{Batman}} Ra's al Ghul]] ComicBook/RasAlGhul rejuvenate him every century or so.
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* The space marines' biological enhancements in ''TabletopGame/{{Warhammer 40000}}'' setting allow them to live a millennium or more. Unenhanced human nobles have "rejuvenat", implied to be made from children.

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* The space marines' biological enhancements in ''TabletopGame/{{Warhammer 40000}}'' setting allow them to live a millennium or more. Unenhanced human nobles and dignitaries have "rejuvenat", implied "rejuvenat" or simply "juveant" treatments, enabling them to be made from children.live several centuries longer than ordinary humans. Some sources imply that certain variants of these procedures use raw materials [[PoweredByAForsakenChild From Living Children.]]
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* ''Webcomic/TheDragonDoctors'' reverse-engineered the effects of a FountainOfYouth. The Fountain itself is a deadly lake that regresses everything to nothing within its radius, but learning its magic has allowed other characters to get regular rejuvenation treatments.

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* ''Webcomic/TheDragonDoctors'' ''Webcomic/TheDragonDoctors'': The effects of a FountainOfYouth were reverse-engineered the effects of about a FountainOfYouth. century earlier. The Fountain itself is a deadly lake that regresses everything to nothing within its radius, but learning its magic has allowed other characters to get regular rejuvenation treatments.
treatments. In Mori's backstory it is shown that she helped discover it and was rather old before someone tried to kill her by dunking her head in the lake, she went from about 60 to 20, she also adopted the sole survivor of the previous team to the area who had been regressed to a baby.
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* In ''TabletopGame/ArsMagica'', Hermetic Magi are able to create a longevity ritual that can drastically slow the aging process. The ''Mysteries'' sourcebook provides a significantly more powerful version in the form of an alchemical Elixir of Life.
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** The sarcophagus can extend the life of a human without a [[PuppeteerParasite Goa'uld]] for 700 years or so, hosts for millennia. Unfortunately it makes the user megalomaniacal

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** The sarcophagus can extend the life of a human without a [[PuppeteerParasite Goa'uld]] for 700 years or so, hosts for millennia. Unfortunately it makes the user megalomaniacalmegalomaniacal. [[ImmortalityImmorality Because reasons.]]
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* In Wil [=McCarthy=]'s ''The Queendom of Sol'' series, you can "print" a new body for yourself, and then have your mind transferred into it.

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* In Wil [=McCarthy=]'s ''The Queendom of Sol'' series, you can "print" a new body for yourself, and then have your mind transferred into it. In the golden years of the queendom, everyone travels ''everywhere'' by fax, and so has their body reset to a healthy 25 on pretty much a daily basis.
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* Poulsen treatments in ''Creator/RobertReed'''s novel, ''The Remarkables''. It can greatly expand one's life (beyond the already genetically enhanced ~150 year lifespan), though the treatment leaves visible marks - one of the characters who has had extensive treatments has an almost young face, but wrinkled hands and oddly colored skin.

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* Poulsen treatments in ''Creator/RobertReed'''s Creator/RobertReed's novel, ''The Remarkables''. It can greatly expand one's life (beyond the already genetically enhanced ~150 year lifespan), though the treatment leaves visible marks - one of the characters who has had extensive treatments has an almost young face, but wrinkled hands and oddly colored skin.
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* Poulsen treatments in ''Creator/RobertReed'''s novel, ''The Remarkables''. It can greatly expand one's life (beyond the already genetically enhanced ~150 year lifespan), though the treatment leaves visible marks - one of the characters who has had extensive treatments has an almost young face, but wrinkled hands and oddly colored skin.
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* In the ''TheTakeshiKovacsSeries'', people are implanted with "cortical stacks" at birth that record one's brain state so that when they die, they can be "resleeved" in a new body.

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* In the ''TheTakeshiKovacsSeries'', ''Literature/TakeshiKovacs'' series, people are implanted with "cortical stacks" at birth that record one's brain state so that when they die, they can be "resleeved" in a new body.
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[[AC:ComicBooks]]
* The Lazarus Pits used by [[Franchise/{{Batman}} Ra's al Ghul]] rejuvenate him every century or so.

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* The prolong treatments in the ''Literature/HonorHarrington'' books. It's most blatant example is Honor's mother, Allison, who at 90 is still very attractive and capable of bearing children. And since Honor is a second generation recipient,she's likely to live even longer.

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* The prolong treatments in the ''Literature/HonorHarrington'' books. It's most blatant example is Honor's mother, Allison, who at 90 is still very attractive and capable of bearing children. And since Honor is a second generation recipient,she's recipient, she's likely to live even longer.longer. Also, people not only look very young for decades, they also have the hormonal levels corresponding with the apparent age ''for decades''.
** In the latter books, prolong becomes a key indicator of how socially and economically evolved a planet is: if you look old, it likely means you're poor. When the [[spoiler:Star Empire of Manticore]] is created, receiving prolong is made a fundamental, inalienable right of every citizen.
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In many science-fiction works, both CyberPunk and SpaceOpera, it's not uncommon for humans, or at least the upper classes, to [[LongLived live for centuries]]. Most often this reason is some form of technology ranging from alien substances to gene therapy to nanomachines.

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In many science-fiction works, both CyberPunk and SpaceOpera, it's not uncommon for humans, or at least the upper classes, to [[LongLived live for centuries]]. Most often this the reason for this is some form of technology ranging from alien substances to gene therapy to nanomachines.
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[[AC:Tabletop Games]]
* Anagathic drugs in ''TabletopGame/{{Traveller}}''.

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[[AC:Tabletop Games]]
Games]]
* Anagathic drugs in ''TabletopGame/{{Traveller}}''.''TabletopGame/{{Traveller}}'', frequently banned or controlled. Require monthly doses or the character is forced to make an aging roll.



* ''VideoGame/TheSims 2'' features a carnivorous plant that produces a substance that, when drunk, gives a Sim an extra day of life.

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* ''VideoGame/TheSims 2'' features a carnivorous plant (the cowplant) that produces a substance that, when drunk, gives a Sim an extra day of life.
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* In Creator/VernorVinge's ''Literature/RainbowsEnd'': the Venn-Kurasawa treatments. They only work for one in a thousand, but for those they do work for, they can restore the appearance of youth, and add many years of actual lifespan. Robert Gu is one of the lucky few who respond to the treatments.
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[[AC: Live Active TV]]
* ''Series/StargateSG1'', several examples, all with severe side effects:
** The sarcophagus can extend the life of a human without a [[PuppeteerParasite Goa'uld]] for 700 years or so, hosts for millennia. Unfortunately it makes the user megalomaniacal
** In the episode ''2010'' the Aschen give earth a life-extension drug that serves to explain why SG-1 hadn't aged at all in ten years. It also turned out to cause sterility, as part of an Aschen plot to depopulate earth so they could turn it into an agricultural colony. Necessitating TimeTravel to prevent the earth-Aschen alliance.


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[[AC: Web Original]]
* In ''OrionsArm'' most [[HumanSubspecies nearbaselines]] are genetically engineered to live about 500 years. But due to medical nanotechnology and brain uploading most in the Sephirotic Empires live to 3,000 before succumbing to ennui or [[AscendToAHigherPlaneOfExistence transcending]].
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* In ''Webcomic/QuantumVibe'', rejuvenation treatments are just as readily available. One of the main characters is reportedly in his third century, but there's evidence that he's ''[[ReallySevenHundredYearsOld over 500 years old.]]''
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-> ''"I plan to live forever of course, but barring that, I'd settle for a couple thousand years. Even five hundred would be pretty nice."''
-->-- '''CEO Nwabudike Morgan - [=MorganLink=] [=3DVision=] Interview''', ''SidMeiersAlphaCentauri''
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* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us", which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain.

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* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us", which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain. The species from whose computer equipment carbosilicate amorphs has evolved already made themselves immortal and ran into several layers of problems. Still, there's a few remaining individuals alive and sane after their twelve million of Terran years, "[[http://www.schlockmercenary.com/2007-07-14 give or take a little bit]]".
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* ''TabletopGame/{{Shadowrun}}'' features a number of age rejuvenation treatments. Leonization, the most expensive, restores physical age to approximately 21, a life span extension is a one-time procedure that adds 10 years to your life, while physical vigor simply counters the physical side effects of aging.
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* ''Webcomic/TheDragonDoctors'' reverse-engineered the effects of a FountainOfYouth. The Fountain itself is a deadly lake that regresses everything to nothing within its radius, but learning its magic has allowed other characters to get regular rejuvenation treatments.
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* In ''Turnabout'' by Margaret Peterson Haddix, the government is working on a top-secret experiment in 2000 to reverse the aging process. And it works - the main characters, who were extremely elderly and would have died before long, are given the chance to grow young again. Unfortunately, they haven't figured out a working way to ''stop'' the un-aging.

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Examples:

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Examples:
!!Examples:



* Rejuv in the ''AllianceUnion'' universe is made from a lifeform native to Cyteen and delays aging up to a century. Side effects include sterility and loss of hair color.
* The spice melange in ''{{Dune}}'' can extend lifespans up to 300 years.
* The ''[[RedMarsTrilogy Red Mars]]'' series features a specialized gene therapy referred to as a "gerontological treatment". The books span over two hundred years and most the major characters, many of whom where ''already'' in their 40s and 50s at the start of the series, are alive and active that entire time due to repeated use of the treatment.
* In Creator/RobertAHeinlein's future history series, particularly ''MethuselahsChildren'' and ''TimeEnoughForLove'', humanity develops a form of rejuvenation through blood replacement after a group of naturally long-lived people reveal themselves and then hijack a starship when the rest of the species demand they reveal their "secret". Later more advanced methods including complete body replacement are developed.

to:

* Rejuv in the ''AllianceUnion'' ''Literature/AllianceUnion'' universe is made from a lifeform native to Cyteen and delays aging up to a century. Side effects include sterility and loss of hair color.
* The spice melange in ''{{Dune}}'' ''Literature/{{Dune}}'' can extend lifespans up to 300 years.
* The ''[[RedMarsTrilogy Red Mars]]'' series ''Literature/RedMarsTrilogy'' features a specialized gene therapy referred to as a "gerontological treatment". The books span over two hundred years and most the major characters, many of whom where were ''already'' in their 40s and 50s at the start of the series, are alive and active that entire time due to repeated use of the treatment.
treatment.
* In Creator/RobertAHeinlein's future history series, particularly ''MethuselahsChildren'' ''Literature/MethuselahsChildren'' and ''TimeEnoughForLove'', ''Literature/TimeEnoughForLove'', humanity develops a form of rejuvenation through blood replacement after a group of naturally long-lived people reveal themselves and then hijack a starship when the rest of the species demand they reveal their "secret". Later more advanced methods including complete body replacement are developed.



* In JohnScalzi's ''OldMansWar'', rejuvenation treatment via consciousness transfer to a genetically enhanced body is only available to military personnel--and the minimum age for joining the military is 75.

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* In JohnScalzi's ''OldMansWar'', ''Literature/OldMansWar'', rejuvenation treatment via consciousness transfer to a genetically enhanced body is only available to military personnel--and the minimum age for joining the military is 75.



* LarryNiven's ''KnownSpace'' stories

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* LarryNiven's ''KnownSpace'' ''Literature/KnownSpace'' stories



** ''{{Ringworld}}''. There is an equivalent to boosterspice available on the title space construct.

to:

** ''{{Ringworld}}''.''Literature/{{Ringworld}}''. There is an equivalent to boosterspice available on the title space construct.



* Anagathic drugs in ''{{Traveller}}''.
* A couple of nanosymbionts in ''GURPS TranshumanSpace'' extend life expectancy by 10 years and expensive "rejuvenation" treatments can actually reverse the aging process.
* The space marines' biological enhancements in ''{{Warhammer40000}}'' allow them to live a millenium or more. Unenhanced human nobles have "rejuvenat" implied to be made from children.

to:

* Anagathic drugs in ''{{Traveller}}''.
''TabletopGame/{{Traveller}}''.
* A couple of nanosymbionts in ''GURPS TranshumanSpace'' TabletopGame/TranshumanSpace'' extend life expectancy by 10 years and expensive "rejuvenation" treatments can actually reverse the aging process.
* The space marines' biological enhancements in ''{{Warhammer40000}}'' ''TabletopGame/{{Warhammer 40000}}'' setting allow them to live a millenium millennium or more. Unenhanced human nobles have "rejuvenat" "rejuvenat", implied to be made from children.



* ''TheSims 2'' features a carnivorous plant that produces a substance that, when drunk, gives a Sim an extra day of life.

to:

* ''TheSims ''VideoGame/TheSims 2'' features a carnivorous plant that produces a substance that, when drunk, gives a Sim an extra day of life.



* In ''WesternAnimation/BatmanTheAnimatedSeries'' Poison Ivy under the guise of Dr. Demeter offers this treatment to rich industrialists but in reality is turning them into trees as karmic justice for their enviromental destruction. She has no qualms about going after thier friends or loved ones either.

to:

* In ''WesternAnimation/BatmanTheAnimatedSeries'' Poison Ivy under the guise of Dr. Demeter offers this treatment to rich industrialists but in reality is turning them into trees as karmic justice for their enviromental destruction. She has no qualms about going after thier their friends or loved ones either.as well.
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[[AC: Western Animation]]
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* The space marines' biological enhancements in ''Warhammer40000'' allow them to live a millenium or more. Unenhanced human nobles have "rejuvenat" implied to be made from children.

to:

* The space marines' biological enhancements in ''Warhammer40000'' ''{{Warhammer40000}}'' allow them to live a millenium or more. Unenhanced human nobles have "rejuvenat" implied to be made from children.
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None

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* In ''WesternAnimation/BatmanTheAnimatedSeries'' Poison Ivy under the guise of Dr. Demeter offers this treatment to rich industrialists but in reality is turning them into trees as karmic justice for their enviromental destruction. She has no qualms about going after thier friends or loved ones either.
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A subtrope of ImmortalityInducer, usually results in LongLived or TheAgeless.

to:

A subtrope of ImmortalityInducer, usually results in LongLived or TheAgeless. BrainUploading counts when the brain is downloaded into a clone or other biological body, but not if into a machine.

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Changed: 2140

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[[AC: Film]]
* In ''Film/InTime'' the aging gene has been "shut down" freezing aging at 25. But to prevent overpopulation and present an anvilicious message about income disparity people are programmed to die at a certain time and use their remaining time as currency.

[[AC: Literature]]
* Rejuv in the AllianceUnion universe is made from a lifeform native to Cyteen and delays aging up to a century. Side effects include sterility and loss of hair color.
* The spice melange in {{Dune}} can extend lifespans up to three hundred years.
* The ''[[RedMarsTrilogy Red Mars]]'' series features a specialized gene therapy referred to as a "gerontological treatment". The books span over two hundred years and most the major characters, many of whom where ''already'' in their 40s-50s at the start of the series, are alive and active that entire time due to repeated use of the treatment.
* In Heinlein's future history series, particularly ''MethuselahsChildren'' and ''TimeEnoughForLove'' humanity develops a form of rejuvenation through blood replacement after a group of naturally long-lived people reveal themselves and then hijack a starship when the rest of the species demand they reveal their "secret". Later more advanced methods including complete body replacement are developed.
* In the ''TheTakeshiKovacsSeries'' people are implanted with "cortical stacks" at birth that record one's brain state so that when they die they can be "resleeved" in a new body.

to:

\n[[AC: Film]]\n----
Examples:

[[AC:Film]]
* In ''Film/InTime'' ''Film/InTime'', the aging gene has been "shut down" down", freezing aging at 25. But to prevent overpopulation and present an anvilicious message about income disparity disparity, people are programmed to die at a certain time and use their remaining time as currency.

[[AC: Literature]]
[[AC:Literature]]
* Rejuv in the AllianceUnion ''AllianceUnion'' universe is made from a lifeform native to Cyteen and delays aging up to a century. Side effects include sterility and loss of hair color.
* The spice melange in {{Dune}} ''{{Dune}}'' can extend lifespans up to three hundred 300 years.
* The ''[[RedMarsTrilogy Red Mars]]'' series features a specialized gene therapy referred to as a "gerontological treatment". The books span over two hundred years and most the major characters, many of whom where ''already'' in their 40s-50s 40s and 50s at the start of the series, are alive and active that entire time due to repeated use of the treatment.
* In Heinlein's Creator/RobertAHeinlein's future history series, particularly ''MethuselahsChildren'' and ''TimeEnoughForLove'' ''TimeEnoughForLove'', humanity develops a form of rejuvenation through blood replacement after a group of naturally long-lived people reveal themselves and then hijack a starship when the rest of the species demand they reveal their "secret". Later more advanced methods including complete body replacement are developed.
* In the ''TheTakeshiKovacsSeries'' ''TheTakeshiKovacsSeries'', people are implanted with "cortical stacks" at birth that record one's brain state so that when they die die, they can be "resleeved" in a new body.



* In JohnScalzi's ''OldMansWar'', rejuvenation treatment via consciousness transfer to a genetically enhanced body is only available to military personnel--and the minimum age for joining the military is seventy-five.

to:

* In JohnScalzi's ''OldMansWar'', rejuvenation treatment via consciousness transfer to a genetically enhanced body is only available to military personnel--and the minimum age for joining the military is seventy-five.75.



* In John Norman's ''Literature/{{Gor}}'' novels, the Caste of Physicians developed a treatment called the Stabilization Serums, which allowed the recipient to live for hundreds of years. The Priest-Kings, the PhysicalGods of the setting have a similar treatment, the oldest being about 5,000,000 years old.

[[AC: Tabletop Games]]
* Anagathic drugs in {{Traveller}}.
* A couple of nanosymbionts in GURPS TranshumanSpace extend life expectancy by 10 years and expensive "rejuvenation" treatments can actually reverse the aging process.
* The space marines' biological enhancements in Warhammer40000 allow them to live a millenium or more. Unenhanced human nobles have "rejuvenat" implied to be made from children.

to:

* In John Norman's ''Literature/{{Gor}}'' novels, the Caste of Physicians developed a treatment called the Stabilization Serums, which allowed the recipient to live for hundreds of years. The Priest-Kings, the PhysicalGods of the setting setting, have a similar treatment, the oldest being about 5,000,000 years old.

[[AC: Tabletop [[AC:Tabletop Games]]
* Anagathic drugs in {{Traveller}}.
''{{Traveller}}''.
* A couple of nanosymbionts in GURPS TranshumanSpace ''GURPS TranshumanSpace'' extend life expectancy by 10 years and expensive "rejuvenation" treatments can actually reverse the aging process.
* The space marines' biological enhancements in Warhammer40000 ''Warhammer40000'' allow them to live a millenium or more. Unenhanced human nobles have "rejuvenat" implied to be made from children.



[[AC: Video Games]]
* TheSims 2 features a carnivorous plant that produces a substance that when drunk gives a Sim an extra day of life.
* In the ''VideoGame/MassEffect'' series humans commonly live to 150 or so due to gene therapies and drugs. Putting us in the mid-range for lifespans in that universe.

to:

[[AC: Video [[AC:Video Games]]
* TheSims 2 ''TheSims 2'' features a carnivorous plant that produces a substance that that, when drunk drunk, gives a Sim an extra day of life.
* In the ''VideoGame/MassEffect'' series series, humans commonly live to 150 or so due to gene therapies and drugs. Putting This puts us in the mid-range for lifespans in that universe.



** There is a secret project called 'The Longevity Vaccine' and another one called 'Clinical Immortality'.
** It is mentioned that the player character goes through some sort of gene therapy on a regular basis to explain how they stay alive for the full five centuries of the game.

to:

** There is a secret project called 'The Longevity Vaccine' and another one called 'Clinical Immortality'.
** It is mentioned that the player character goes through some sort of gene therapy on a regular basis to explain how they stay he stays alive for the full five centuries of the game.



[[AC: Web Comics]]
* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us" which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain.
* In the future of ''Webcomic/{{SSDD}}'' the wealthy are able to afford implants that extend lifespans until an accident kills them. At least two of [[MegaCorp Maytec's]] board of directors are in their fifties and appear to be twenty.
* In ''Webcomic/{{Freefall}}'' life extension drugs are apparently available over the counter. At one point Florence (an [[UpliftedAnimal uplifted]] red wolf) states that her projected lifespan of 160 years is slightly shorter than a human's.
* In ''Webcomic/EscapeFromTerra'' rejuvenation treatments are one of many examples of bio- and nano- technology that are officially banned on earth. Reggie King and Babbette the elder undergo the treatment on Mars, and the first man on Mars is a great-great-great-grandparent who looks no older than thirty.

to:

[[AC: Web Comics]]
[[AC:Webcomics]]
* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us" Laz'r'us", which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain.
* In the future of ''Webcomic/{{SSDD}}'' ''Webcomic/{{SSDD}}'', the wealthy are able to afford implants that extend lifespans until an accident kills them. At least two of [[MegaCorp Maytec's]] board of directors are in their fifties and appear to be twenty.
* In ''Webcomic/{{Freefall}}'' ''Webcomic/{{Freefall}}'', life extension drugs are apparently available over the counter. At one point point, Florence (an [[UpliftedAnimal uplifted]] red wolf) states that her projected lifespan of 160 years is slightly shorter than that of a human's.
human.
* In ''Webcomic/EscapeFromTerra'' ''Webcomic/EscapeFromTerra'', rejuvenation treatments are one of many examples of bio- and nano- technology nanotechnology that are officially banned on earth. Earth. Reggie King and Babbette the elder undergo the treatment on Mars, and the first man on Mars is a great-great-great-grandparent great-great-great-grandfather who looks no older than thirty.30.
----
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In many science-fiction works, both CyberPunk and SpaceOpera, it's not uncommon for humans, or at least the upper classes, to [[LongLived live for centuries]]. Most often this reason is some form of technology ranging from alien substances to gene therapy to nanomachines.

A subtrope of ImmortalityInducer, usually results in LongLived or TheAgeless.

[[AC: Film]]
* In ''Film/InTime'' the aging gene has been "shut down" freezing aging at 25. But to prevent overpopulation and present an anvilicious message about income disparity people are programmed to die at a certain time and use their remaining time as currency.

[[AC: Literature]]
* Rejuv in the AllianceUnion universe is made from a lifeform native to Cyteen and delays aging up to a century. Side effects include sterility and loss of hair color.
* The spice melange in {{Dune}} can extend lifespans up to three hundred years.
* The ''[[RedMarsTrilogy Red Mars]]'' series features a specialized gene therapy referred to as a "gerontological treatment". The books span over two hundred years and most the major characters, many of whom where ''already'' in their 40s-50s at the start of the series, are alive and active that entire time due to repeated use of the treatment.
* In Heinlein's future history series, particularly ''MethuselahsChildren'' and ''TimeEnoughForLove'' humanity develops a form of rejuvenation through blood replacement after a group of naturally long-lived people reveal themselves and then hijack a starship when the rest of the species demand they reveal their "secret". Later more advanced methods including complete body replacement are developed.
* In the ''TheTakeshiKovacsSeries'' people are implanted with "cortical stacks" at birth that record one's brain state so that when they die they can be "resleeved" in a new body.
* In Norman Spinrad's ''Literature/BugJackBarron'', an investigative reporter and consumer advocate begins investigating an organization that provides rejuvenation treatments to the rich and powerful, and finds far more than he bargained for.
* Creator/RogerZelazny:
** In ''Literature/LordOfLight'', the so-called "Gods" (actually mutant humans) have mind-transfer technology that they use to reward or punish people. Be good, and you may end up with a bright, shiny new young body. Be bad, and you may end up with the old, worn-out body left by someone who was good.
** In ''Literature/CreaturesOfLightAndDarkness'', the technologically advanced world of Blis has more-or-less eliminated death by old age. Death is so rare that the few who volunteer for suicide can leave their heirs a legacy by selling tickets to watch the death.
* In JohnScalzi's ''OldMansWar'', rejuvenation treatment via consciousness transfer to a genetically enhanced body is only available to military personnel--and the minimum age for joining the military is seventy-five.
* In Wil [=McCarthy=]'s ''The Queendom of Sol'' series, you can "print" a new body for yourself, and then have your mind transferred into it.
* LarryNiven's ''KnownSpace'' stories
** Boosterspice (a drug derived from genetically engineered ragweed) can tremendously extend the human lifespan.
** ''{{Ringworld}}''. There is an equivalent to boosterspice available on the title space construct.
** ''A World Out of Time'' has an immortality treatment for adults that involves removing impurities from the body.
* The prolong treatments in the ''Literature/HonorHarrington'' books. It's most blatant example is Honor's mother, Allison, who at 90 is still very attractive and capable of bearing children. And since Honor is a second generation recipient,she's likely to live even longer.
* Citizens of ''TheCulture'' are genetically engineered to live for centuries, longer if they feel like it.
* In John Norman's ''Literature/{{Gor}}'' novels, the Caste of Physicians developed a treatment called the Stabilization Serums, which allowed the recipient to live for hundreds of years. The Priest-Kings, the PhysicalGods of the setting have a similar treatment, the oldest being about 5,000,000 years old.

[[AC: Tabletop Games]]
* Anagathic drugs in {{Traveller}}.
* A couple of nanosymbionts in GURPS TranshumanSpace extend life expectancy by 10 years and expensive "rejuvenation" treatments can actually reverse the aging process.
* The space marines' biological enhancements in Warhammer40000 allow them to live a millenium or more. Unenhanced human nobles have "rejuvenat" implied to be made from children.
* The CCG ''TabletopGame/{{Illuminati}}'' has the [[http://media.adamdodson.org/index.php/Illuminati-Card-Game/immortality-serum "immortality serum" card]] that makes a personality indestructible and can also cause an opponent's personality to defect.
* ''TabletopGame/EclipsePhase'' mentions longevity treatments as part of the backstory. Though they're apparently obsolete now (outside the Junta) since longevity is included in most Basic Biomods and BrainUploading is commonplace.

[[AC: Video Games]]
* TheSims 2 features a carnivorous plant that produces a substance that when drunk gives a Sim an extra day of life.
* In the ''VideoGame/MassEffect'' series humans commonly live to 150 or so due to gene therapies and drugs. Putting us in the mid-range for lifespans in that universe.
* Several forms appear in ''Videogame/SidMeiersAlphaCentauri'':
** There is a secret project called 'The Longevity Vaccine' and another one called 'Clinical Immortality'.
** It is mentioned that the player character goes through some sort of gene therapy on a regular basis to explain how they stay alive for the full five centuries of the game.
** One of the other characters is said to have kept a strict 'longevity regimen'.

[[AC: Web Comics]]
* A plot point in ''Webcomic/SchlockMercenary'' is "Project Laz'r'us" which was intended to circumvent humanity's [[WeAreAsMayflies short lifespans]] in comparison to many other sophonts using hyper-advanced nanotechnology. The nannies are also capable of repairing a clinically dead host and even making internal backups of the brain.
* In the future of ''Webcomic/{{SSDD}}'' the wealthy are able to afford implants that extend lifespans until an accident kills them. At least two of [[MegaCorp Maytec's]] board of directors are in their fifties and appear to be twenty.
* In ''Webcomic/{{Freefall}}'' life extension drugs are apparently available over the counter. At one point Florence (an [[UpliftedAnimal uplifted]] red wolf) states that her projected lifespan of 160 years is slightly shorter than a human's.
* In ''Webcomic/EscapeFromTerra'' rejuvenation treatments are one of many examples of bio- and nano- technology that are officially banned on earth. Reggie King and Babbette the elder undergo the treatment on Mars, and the first man on Mars is a great-great-great-grandparent who looks no older than thirty.

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